哈药股份: 哈药集团股份有限公司2025年度可持续发展报告(英文版)

来源:证券之星 2026-04-22 19:25:54
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Sustainability Report
   HARBIN PHARMACEUTICAL GROUP CO., LTD.
        Contents
                                                                                                                                                                            Special Topic: Empowering with a Digital
                                                                                 About
                                             Message from the                                                 2025 Key Performance                    Sustainability        and Intelligent Engine, Building a
About This Report       ??                                      ??               Hapharm                 ??                             ??                             ??                                                  ??
                                             Chairman                                                         in Sustainability                       Management            Foundation for High-Quality Develop-
                                                                                 Group
                                                                                                                                                                            ment Through Technological Innovation
           Governance and Compliance to                              Product System for Value Creation                   Green Operations to Advance                                    Employee Development to Build a
           Solidify a Foundation for Stable                                                                              Low-Carbon Management                                          Safe and Shared Future
           Growth
           Party Building Leadership and     23                      Technological R&D and Innovation    39              Environmental Compliance             67                        Employee Rights and Care           87
           Responsibility Implementation                             Practices                                           Management                                                     Talent Cultivation and Develop-    91
           Construction of Corporate         26                      Technology Ethics                   43              Climate Change Tackling              68                        ment
           Governance System                                         Industrial Cooperation and          44              Energy and Resource Manage-          72                        Occupational Health and Safety     95
           Internal Control and Compliance   31                      Exchange                                            ment                                                           Rural Revitalization Practices     101
           Management                                                Product Quality and Safety          45              Pollutant Emissions                  77                        Public Welfare and Social Action   103
           Culture of Integrity and Honest   35                      Management                                          Waste Management                     79
           Operations                                                Customer Rights and Interests       51              Ecosystem and Biodiversity           82
                                                                     and Service Assurance                               Conservation
                                                                     Supply Chain Management and         55
                                                                     Security
           Appendix
                                                                     Information Security and Privacy    59
           Key Performance Table             109                     Protection
           Index of Indicators               113                     Medication Accessibility Enhance-   60
           Reader Feedback Form              114                     ment
           Report Assurance Statement        116
                                       Message            About                2025 Key                                                 Governance and Compliance                                 Green Operations to    Employee Development
                    About This                                                                    Sustainability                                                       Product System for Value
                                       from the          Hapharm             Performance in                             Special Topic   to Solidify a Foundation for                              Advance Low-Carbon      to Build a Safe and   Appendix           2025 Sustainability Report
                     Report                                                                       Management                                                                   Creation
                                       Chairman           Group               Sustainability                                                   Stable Growth                                         Management              Shared Future
                                                                                                                                             Time Horizon
About This Report                                                                                                                       This Report covers the period from January 1, 2025, to December 31, 2025. To enhance the completeness and comparability of
                                                                                                                                        the information, some content may be appropriately traced back to previous years or extended beyond the reporting period
     Report Explanation                                                                                                                 where necessary.
                                                                                                                                             Sources
PHARMACEUTICAL GROUP CO., LTD. (hereinafter referred to as "Hapharm Group," "the Company," or "we"). Building on the
Company's social responsibility disclosure efforts, this is the ?rst dedicated sustainability report that systematically integrates     The data disclosed in this Report is primarily sourced from the Company's internal statistical data, business management
and expands upon relevant information under the environmental, social, and governance (ESG) framework. It provides a focused            systems, and consolidated information from relevant functional departments. Some data is derived from audited ?nancial
presentation of the Company's management philosophy, key initiatives, and progress in the ?eld of sustainability for the year           reports or third-party professional institutions. The Company adheres to the principles of authenticity, accuracy, and complete-
holders regarding the Company's sustainability work.
                                                                                                                                             How to Obtain This Report
     Materiality                                                                                                                        This Report is published in electronic format and can be accessed and obtained from the website of the Shanghai Stock
                                                                                                                                        Exchange (www.sse.com.cn) or the of?cial website of Hapharm Group (www.hayao.com).This Report is available in both Chinese
The Company conducted a double materiality assessment on ESG-related topics for 2025, comprehensively identifying and                   and English versions. In case of any discrepancy between the two versions, the Chinese version shall prevail.
evaluating the impact of each topic on the Company's ?nancial position, stakeholders, and the environment and society. For the
speci?c process and results of the double materiality assessment, please refer to the "Double Materiality Analysis" chapter of
                                                                                                                                             De?nitions
this Report.
     Quantitative                                                                                                                                      Term                  Refers to                                             De?nition
For all quantitative indicators in this Report, their measurement scope, statistical methods, relevant assumptions, and the sourc-       Hapharm Group, the Company           Refers to       Harbin Pharmaceutical Group Co., Ltd.
es of calculation tools or conversion factors used (if applicable) are explained accordingly to enhance the transparency and             Harbin Pharmaceutical Group,         Refers to       Harbin Pharmaceutical Group Holding Co., Ltd. (HPGC)
comprehensibility of the information disclosed.                                                                                          the Group
                                                                                                                                         This Report                          Refers to       2025 Sustainability Report of Hapharm Group
     Balance
                                                                                                                                         Reporting period, this year          Refers to       The period from January 1, 2025 to December 31, 2025
This Report strives to re?ect the Company's management initiatives and phased achievements in the environmental, social, and
corporate governance ?elds in a true, fair, and comprehensive manner. It aims to avoid improperly in?uencing the judgment and            Hayao General Factory                Refers to       Harbin Pharmaceutical Group General Factory
decisions of report users through selective disclosure, information omission, or improper presentation.                                  Hayao No.6 Factory                   Refers to       Harbin Pharmaceutical Group No.6 Pharmaceutical Factory
     Consistency                                                                                                                         Sanchine                             Refers to       Harbin Pharm Group Sanjing Pharmaceutical Co., Ltd.
As this is the Company's ?rst sustainability report prepared under the ESG framework, the Company will, unless otherwise speci-          Sanjing Mingshui                     Refers to       Harbin Pharmaceutical Group Sanjing Mingshui Pharmaceutical Co., Ltd.
?ed or in special circumstances, continuously optimize and improve its statistical scope and disclosure methods for sustainabili-
                                                                                                                                         Shiyitang Chinese Medicine           Refers to       Harbin Shiyitang Chinese Medicine Co., Ltd.
ty-related information disclosure based on existing disclosures. The Company will maintain relative consistency in disclosure
principles and methods to enhance the continuity and comparability of the information disclosed.                                         Renmintongtai                        Refers to       Harbin Pharmaceutical Group Renmintongtai Pharmaceutical Co., Ltd.
                                                                                                                                         Logistics Center                     Refers to       Harbin Pharmaceutical Group Harbin Pharmaceutical Commercial Co., Ltd.
     Preparation Basis                                                                                                                   Pharmaceutical Branch                Refers to       Pharmaceutical Branch of Hapharm Group Pharmaceutical Co., Ltd.
This Report has been prepared in accordance with the Guidelines No. 14 of Shanghai Stock Exchange for Self-Regulation of                 Second Chinese Medicine              Refers to       Harbin Pharmaceutical Group Second Chinese Medicine Factory
Listed Companies – Sustainability Report (Trial) issued by the Shanghai Stock Exchange (SSE). It also references the Corporate           Factory
Sustainability Disclosure Standards – Basic Standards (Trial) issued by nine departments including the Ministry of Finance of the        Marketing Company                    Refers to       Harbin Pharmaceutical Group Marketing Co., Ltd.
People's Republic of China, the Global Reporting Initiative (GRI) Standards issued by the Global Sustainability Standards Board                                                               GNC China is jointly composed of GNC Hong Kong, GNC Trading,
                                                                                                                                         GNC China                            Refers to
(GSSB), IFRS S1 General Requirements for Disclosure of Sustainability-related Financial Information and IFRS S2 Climate-related                                                               Food Technology and Harbin Pharmaceutical Hong Kong II
Disclosures issued by the International Sustainability Standards Board (ISSB), the recommendations of the Task Force on                  GMP                                  Refers to       Good Manufacturing Practice
Climate-related Financial Disclosures (TCFD), and the United Nations Sustainable Development Goals (UN SDGs).
                                                                                                                                         GSP                                  Refers to       Good Supply Practice for Drugs
     Reporting Scope
                                                                                                                                         GLP                                  Refers to       Good Laboratory Practice
                                                                                                                                         RMB, ten thousand yuan,
                                                                                                                                         hundred million yuan                 Refers to       RMB yuan, ten thousand yuan, hundred million yuan
In principle, this Report covers HARBIN PHARMACEUTICAL GROUP CO., LTD. and its subsidiaries included in the consolidated
?nancial statements. Where individual indicators do not cover all entities due to statistical scope, business nature, or data
availability, corresponding explanations have been provided in the report.
                                        Message            About              2025 Key                                                   Governance and Compliance                                 Green Operations to   Employee Development
                     About This                                                                    Sustainability                                                       Product System for Value
                                        from the          Hapharm           Performance in                               Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix        2025 Sustainability Report
                      Report                                                                       Management                                                                   Creation
                                        Chairman           Group             Sustainability                                                     Stable Growth                                         Management             Shared Future
       Message from the Chairman
                                                                                                                                                    Focusing on present development to solidify foundations for long-term growth; looking ahead to drive
                                                                                                                                                    transformation and foster momentum through innovation.
                                                                                                                                                  Over the past year, the Company has continued to re?ne its modern corporate governance system, treating compli-
                                                                                                                                                  ant operations and risk prevention and control as essential pillars of stable operations. Through a series of institu-
                                                                                                                                                  tional arrangements, it has continuously enhanced decision-making transparency and management standardiza-
                                                                                                                                                  tion. At the same time, the Company has steadfastly advanced technological innovation and digital
                                                                                                                                                  transformation—from optimizing its R&D system to implementing smart manufacturing practices, and from quality
                                                                                                                                                  data governance to reengineering management processes—creating synergy between technology and manage-
                                                                                                                                                  ment to embed reform outcomes as organizational capabilities and drivers of development. The Company ?rmly
                                                                                                                                                  believes that only by building solid foundations and pursuing deep innovation can an enterprise maintain resilience
                                                                                                                                                  amid complex and changing environments and steadily advance toward longer-term development.
                                                                                                                                                    Upholding quality as the cornerstone to honor its original mission, and prioritizing responsibility to
                                                                                                                                                    protect health; building trust through dedicated service and demonstrating value through responsible
                                                                                                                                                    actions. The pharmaceutical industry carries the public's high expectations for safety and ef?cacy.
                                                                                                                                                  The Company continues to strengthen its full-lifecycle quality management and pharmacovigilance systems,
                                                                                                                                                  shifting risk identi?cation and process controls upstream to the R&D and production stages. Through rigorous
                                                                                                                                                  quality process management, it ensures that every medicine meets the test of standards and time. Concurrently,
                                                                                                                                                  the Company continuously enhances customer service capabilities and medication accessibility by providing
                                                                                                                                                  professional pharmacy support and developing frontline services to better align health services with societal
                                                                                                                                                  needs. For Hapharm, quality is not merely a baseline for survival but a solemn commitment to the public and the
                                                                                                                                                  fundamental basis for sustained and stable development.
                                                                                                      HARBIN PHARMACEUTICAL                         Embracing green trends to promote sustainable development and expanding horizons through syner-
                                                                                                      GROUP CO., LTD.                               gistic collaboration; caring for employees to build collective strength and co-creating an ecosystem
                                                                                                                                                    for a shared future.
                                                                                                      Party Secretary and Chairman
                                                                                                                                                  In response to resource and environmental constraints, the Company integrates green principles throughout its
                                                                                                                                                  production and operations, continuously advancing energy conservation, consumption reduction, and environ-
                                                                                                                                                  mental protection to ensure more resilient and responsible development. Meanwhile, the Company places great
                                                                                                                                                  emphasis on employee development and industrial collaboration, fostering talent, promoting industry-aca-
                                                                                                                                                  demia-research partnerships, and engaging in social practices to drive mutual progress among the enterprise, its
                                                                                                                                                  partners, communities, and the broader industry. The Company deeply understands that genuine sustainability is
                                                                                                                                                  a process in which enterprises and society mutually empower and share outcomes.
  As times evolve, so do health needs; as the industry progresses, responsibilities deepen.                                                         Looking ahead with steadfast resolve to create long-term value; walking hand-in-hand toward a shared
                                                                                                                                                    vision and co-writing a new chapter in health.
Standing at a new stage of profound transformation in the pharmaceutical and healthcare sector, the Company recognizes with                       Going forward, sustainability will remain a critical benchmark for measuring corporate resilience and governance
increasing clarity that the value of a pharmaceutical enterprise lies not only in its scale and performance but also in its reverence             maturity. Hapharm Group will leverage a stronger governance foundation, a more determined pace of innovation,
for life and health, its commitment to social responsibility, and its continuous investment in long-term sustainability. Hapharm                  and a more open approach to responsibility to translate sustainability principles into enduring value creation. The
Group has always upheld safeguarding public health as its founding mission, closely integrating high-quality development with                     Company is committed to advancing alongside all stakeholders, aligned in the mission of safeguarding public
social value creation. This year, the Company is releasing its sustainability report for the ?rst time under a systematic ESG frame-              health, ensuring that corporate growth and social progress reinforce each other, and jointly crafting a new chapter
work. This represents both a comprehensive review of years of governance practices and developmental achievements and marks                       of high-quality development for Hapharm's future through accumulated trust and shared value over time.
a signi?cant upgrade in Hapharm's development philosophy, management systems, and expression of responsibility. It re?ects the
Company's ?rm commitment to advancing high-quality development with greater transparency, standardization, and a long-term
orientation.
                                        Message             About             2025 Key                                                       Governance and Compliance                                 Green Operations to   Employee Development
                     About This                                                                   Sustainability                                                            Product System for Value
                                        from the           Hapharm          Performance in                            Special Topic          to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix           2025 Sustainability Report
                      Report                                                                      Management                                                                        Creation
                                        Chairman            Group            Sustainability                                                         Stable Growth                                         Management             Shared Future
About Hapharm Group
      Company Pro?le
The Company focuses on the pharmaceutical and healthcare industry, primarily engaging in pharmaceutical research and develop-             The Company’s pharmaceutical R&D and manufacturing business covers chemical drugs, traditional Chinese medicine, biologics,
ment, manufacturing, wholesale and retail businesses. It is a large domestic high-tech pharmaceutical enterprise integrating R&D,         healthcare products, medical devices and aesthetic medicine products. Its product portfolio focuses on ?ve major therapeutic
manufacturing and sales. According to the industry classi?cation standards issued by the China Association for Public Companies,          areas, including cardiovascular and cerebrovascular diseases, digestive and metabolic systems, respiratory systems, anti-infec-
the Company belongs to the pharmaceutical manufacturing industry (C27). The Company was listed on the Shanghai Stock                      tives and anti-tumor treatments, with more than 500 products currently in production and on sale. Major products include Zinc
Exchange in June 1993 (Hapharm Group, 600664.SH), becoming the ?rst listed company in China’s pharmaceutical industry and                 Gluconate Oral Solution, HAYAO Calcium-Iron-Zinc Oral Liquid, Compound Calcium Gluconate Oral Solution, Erythropoietin
the ?rst listed company in Heilongjiang Province.                                                                                         Injection, Amoxicillin Capsules, Shuanghuanglian Oral Liquid, Penicillin Sodium for Injection, Qufeng Gutong Gel Patch, Lacidipine
                                                                                                                                          Tablets and Pediatric Paracetamol, Arti?cial Cow-Bezoar and Chlorphenamine Maleate Granules.
During its development, the Company has continuously optimized its business structure and integrated resources. In 2015, the
Company reorganized its assets and business segments through asset restructuring, establishing a pharmaceutical commercial                The Company’s pharmaceutical wholesale and retail business is primarily conducted through its listed subsidiary, Renmin Tongtai,
listing platform (Renmin Tongtai, 600829.SH) and forming a business layout in which pharmaceutical manufacturing and pharma-              a well-known regional pharmaceutical distribution enterprise and the largest pharmaceutical commercial company in Heilongjiang
ceutical distribution operate relatively independently while developing in coordination.                                                  Province. Renmin Tongtai’s main businesses include pharmaceutical wholesale, pharmaceutical retail, pharmaceutical logistics
                                                                                                                                          services and medical services. Its operations cover chemical drugs, proprietary Chinese medicines and biologics, as well as the
                                                                                                                                          sale of medical devices, Chinese herbal decoction pieces, health foods, daily necessities, glassware and chemical reagents.
             The Company was listed on the                                ?rst listed company
             Shanghai Stock Exchange in June
                                                                          becoming the ?rst listed company in                                                                                                                    600829.SH
                                                                          China's pharmaceutical industry and                                                                                                                    created Renmintongtai
                                                                          the ?rst listed company in Heilongji-                                                                                                                  (stock code: 600829.SH) as
                                                                          ang Province.                                                                                                                                          its listed platform for
                                                                                                                                                                                                                                 pharmaceutical commercial
                                                                                                                                                                                                                                 activities.
                                                                                                                                                Over 500
                                                                                                                                                in-production and
                                                                                                                   Human Erythropoietin
                                                                                                                   Injection
                                                                                                                                                marketed
                                                                                                                                                                                        Shuanghuanglian Oral
                                                                                                                                                speci?cations                           Liquid
                                                    Compound Calcium Gluconate
                                                    Oral Solution
        Zinc Gluconate Oral Solution
                                                                                                                                                                                                                                               GNC Vitapak Daily Nutrition Pack
                                                                                              Hayao Brand Calcium-Iron-Zinc
                                                                                              Oral Liquid
                                                                                                                                                                                                            Lacidipine Tablets
                                                                                                                                                      Amoxicillin Capsules
                                          Message           About              2025 Key                                               Governance and Compliance                                        Green Operations to     Employee Development
                      About This                                                                Sustainability                                                            Product System for Value
                                          from the         Hapharm           Performance in                           Special Topic   to Solidify a Foundation for                                     Advance Low-Carbon       to Build a Safe and       Appendix                 2025 Sustainability Report
                       Report                                                                   Management                                                                        Creation
                                          Chairman          Group             Sustainability                                                 Stable Growth                                                Management               Shared Future
      Company Honors                                                                                                                  2025 Milestones
 Brand and product market recognition
                                                                                                                                                                                                                   Sanjing Zinc Gluconate Oral Solution (Strawberry Flavor) obtained its
                                                                                                                                             The Oral Liquid No. 1 Workshop of Sanchine and the                    ?ling certi?cate and completed the license expansion. This project
                                                                                                                                             Solid Dosage Form No. 1 Workshop of Hayao No.6                        received approval for a health food ?ling certi?cate, marking the ?rst-ever
                                                                                                                                             Factory were recognized as "Heilongjiang Province                     approved zinc supplement in sachet format, signifying that the Company's
                                                                                                                                             Advanced-Level Digital Workshops."                                    R&D capabilities and product quality in the health industry have been
     CPHCF Award for Best-Selling                      West Lake Award for Most
       Products in China's Retail                     Popular Star Single Product                     2025 Healthy China                                                                                           highly recognized by authoritative institutions.Sanjing Calcium Gluconate
        Pharmaceutical Market                                in Pharmacies                                Brand List                                                                                               Calcium Lactate Oral Liquid (Peach Flavor) obtained its ?ling certi?cate
      Harbin Pharm Group Sanjing                      Harbin Pharmaceutical Group                 Harbin Pharm Group Sanjing                                                                                       and completed the license expansion. As the Company's ?rst calcium
        Pharmaceutical Co., Ltd.                      No.6 Pharmaceutical Factory                  Pharmaceutical Co., Ltd.                                                                                        supplement in sachet format, it represents a "zero-to-one" breakthrough in
                                                                                                                                                          The revitalization and industrial                        this ?eld.
                                                                                                                                                          upgrading project for the Xuefu Road
                                                                                                                                                          plant area of Hayao General Factory was
                                                                                                                                                          launched to transform it into an
                                                                                                                                                          "Industry+N" integrated industrial park.
                                                                                                                                                                                                                               Acanthopanax Senticosus Base of
                                                      Innovation and market practice achievements                                                                                                                              Harbin Pharmaceutical Group Shiyitang
                                                                                                                                                                                                                               Co., Ltd. and Second Chinese Medicine
                                                                                                                                                                                                                               Factory under Harbin Shiyitang Chinese
                                                                                                                                                                                                                               Medicine Co., Ltd. successfully passed
                                                                                                                                                                                                                               the provincial good agricultural practice
                                                                                                                                                                                                                               (GAP) compliance inspection.
         First Batch of Famous Consumer                                                                                                      Renmintongtai ranked 33rd on the "2024
           Product Enterprise Brands in
               Heilongjiang Province                                                                                                         Top 100 Pharmaceutical Retail Enterprises
                                                                                                                                             by Total Sales" list.
            HARBIN PHARMACEUTICAL
                  GROUP CO., LTD.
                                                         West Lake Award for                          West Lake Award for                           Three new products, namely
                                                      Innovative Marketing Case                    Innovative Marketing Case                        Lactulose Oral Solution, Oseltamivir
                                                                                                                                                    Phosphate Dry Suspension and Iron
                                                     Harbin Pharmaceutical Group                   HARBIN PHARMACEUTICAL
                                                          Marketing Co., Ltd.                          GROUP CO., LTD.                              Polymaltose Complex Oral Solution,
 Industry Recognition and Collaborative Impact                                                                                                      have obtained drug registration
                                                                                                                                                    certi?cates. In addition, two active
                                                                                                                                                    pharmaceutical ingredients
                                                                                                                                                    including Calcium Lactate API and
                                                                                                                                                    Iron Polymaltose Complex API have
                                                                                                                                                    been approved for marketing
                                                                                                                                                    application. This further enriches
                                                                                                                                                    the Company’s product portfolio
                                                                                                                                                    and continuously promotes the
                                                                                                                                                    construction of its product pipeline.
      CPHCF Award for Outstanding
      Ful?llment Chain Enterprise in                 Partner in the Pharmaceutical             Silver Award in the Medical and
      China's Pharmaceutical Retail                      Manufacturing Sector                  Health Communication Category
      Renmintongtai Pharmaceutical                    HARBIN PHARMACEUTICAL                      HARBIN PHARMACEUTICAL
              Chain Co., Ltd.                             GROUP CO., LTD.                            GROUP CO., LTD.
                                                                                                                                          Among them, Iron Polymaltose Complex Oral Solution obtained the drug registration certi?cate in January 2026, and Iron Polymaltose Complex API was
                                                                                                                                      approved for marketing application as a chemical active pharmaceutical ingredient in January 2026.
                             Message          About      2025 Key                                                    Governance and Compliance                                    Green Operations to   Employee Development
          About This                                                            Sustainability                                                       Product System for Value
                             from the        Hapharm   Performance in                                Special Topic   to Solidify a Foundation for                                 Advance Low-Carbon     to Build a Safe and     Appendix              2025 Sustainability Report
           Report                                                               Management                                                                   Creation
                             Chairman         Group     Sustainability                                                      Stable Growth                                            Management             Shared Future
        Economic performance                                       Governance performance                                                  Social performance
      Operating revenue of RMB                               Independent directors accounted                                         Total R&D investment:                       Total number of valid patents held:           14 responsible marketing
                                                                                                                                     Performed      761 supplier                DTP pharmacies served a cumulative             Total number of employees:
      Total assets: RMB                                      Percentage of female directors:
                                                                                                                                     training sessions                          total of   250,000 person-times 10,039 persons
                                                                                                                                                                                                                               Number of people assisted
                                                                                                                                     Total employee training duration:           Employee trade union coverage
                                                                                                                                                                                                                               through the Company's public
      Net pro?t attributable to sharehold-                                                                                           248,712.2 hours                             rate:   100 %
                                                                                                                                                                                                                               welfare initiatives:   5,682
      ers of the listed company: RMB
      Basic earnings per share: RMB
                                                                                                                                           Environmental performance
      Net assets attributable to share-
      holders of the listed company: RMB
                                                                                                                                     Total environmental management                                     Total environmental protection investment:
                                                                                                                                     training duration:   3,569           hours                         RMB   15.8187 million
      Total tax payment: RMB                                 100 % employee signing rate for compli-                                 Photovoltaic power generation:                                     Percentage of waste reclaimed and reused:
                                           Message             About              2025 Key                                                      Governance and Compliance                                   Green Operations to   Employee Development
                      About This                                                                        Sustainability                                                         Product System for Value
                                           from the           Hapharm           Performance in                                  Special Topic   to Solidify a Foundation for                                Advance Low-Carbon     to Build a Safe and    Appendix               2025 Sustainability Report
                       Report                                                                           Management                                                                     Creation
                                           Chairman            Group             Sustainability                                                        Stable Growth                                           Management             Shared Future
                                                                                                                                                          Stakeholders                                    Topics of concern                              Communication channels
Sustainability Management
                                                                                                                                                                                         Innovation-driven development
                                                                                                                                                                                                                                                Information disclosure
                                                                                                                                                                                         Compliant operation
                                                                                                                                                                                                                                                Investor hotline
                                                                                                                                                                                         Internal control and risk management
Sustainability Management System                                                                                                                        Shareholders and
                                                                                                                                                                                         Corporate governance
                                                                                                                                                                                                                                                Investor communication platform
                                                                                                                                                                                                                                                On-site/telephone research
                                                                                                                                                           investors                     Shareholder rights protection
                                                                                                                                                                                                                                                Social media
                                                                                                                                                                                         Climate change tackling
Aligning with its governance structure and operational realities, the Company has established a sustainability management frame-
work led by the Board of Directors, with participation from management and coordinated implementation by relevant departments,
to research, advance, and supervise sustainability-related matters.
                                                                                                                                                                                                                                                Information disclosure
                                                                                                                                                                                                                                                Investor hotline
                                                                                                                                                                                         Compliant operation
                                                                                                                                                                                                                                                Investor communication platform
                                                                                                                                                                                         Internal control and risk management
                                                                As the coordinating management body for the Company's sustainabili-                          Creditors                                                                          Of?ine meetings
   Strategy and Sustainability                                  ty work, it is responsible for overall supervision and guidance of major                                                                                                        Social media
   Committee                                                    sustainability-related matters, deliberating key topics and submitting
                                                                decision-making recommendations to the Board of Directors.
                                                                                                                                                                                         Employees                                              Employee satisfaction surveys
                                                                Undertake support and coordination responsibilities for the                                                              Corporate governance                                   Internal communication platform
   Of?ce of the Board of                                        Committee's daily operations, and ensure the orderly advancement                      Company employees
   Directors                                                                                                                                                                             Energy usage                                           Employee training
                                                                of sustainability-related topics.
                                                                Implement sustainability requirements in their respective domains                                                                                                               Information disclosure
  Relevant                                                      according to assigned responsibilities, advance measure implementa-                                                       Industry cooperation and exchange                     Event participation
  business and                                                                                                                                                                            Anti-unfair competition                               Of?ine meetings
  functional
                                                                tion, and provide relevant information, data, and execution feedback to              Partners and industry
  departments                                                   establish a collaborative advancement mechanism.                                         associations                                                                           Social media
                                Hapharm Group's sustain-
                               ability governance structure
                                                                                                                                                                                                                                                Information disclosure
                                                                                                                                                                                         Safety and quality of products and services            Customer service hotline
                                                                                                                                                                                         Customer rights and interests protection               Customer satisfaction surveys
In alignment with sustainability-related management requirements and ESG development needs, the Company organizes special-                                                               Responsible marketing                                  Marketing activities
ized ESG training to continuously enhance the overall awareness and understanding of sustainability topics among relevant                                   Customers
                                                                                                                                                                                         Data security and customer privacy protection          After-sales service
management personnel and business units. The training further strengthens compliance and responsibility awareness regarding                                                                                                                     Social media
environmental, social, and governance matters, laying a foundation for subsequent sustainability work and information coordina-
tion.
                                                                                                                                                                                         Circular economy
                                                                                                                                                                                         Supply chain security                                  Supplier communication and exchange
                                                                                                                                                                                         Equal treatment to small and medium-sized              Supplier training and seminars
                                                                                                                                                   Suppliers and contractors             enterprises
           During the reporting period, the Company
                                     ??
                                                                                                                                                                                         Medical accessibility and inclusiveness
        Organized ESG training for          participants                                                                                                                                 Ecosystem and biodiversity conservation
                                                                                                                                                                                                                                                Information disclosure
                                                                                                                                                                                         Pollutant emissions
                                                                                                                                                                                                                                                Social media
                                                                                                                                                                                         Contributions to the society
                                                                                                                                                      Media and the public                                                                      Event participation
                                                                                                                                                                                         Waste disposal
                                                                                                                                                                                         Usage of water resources
Communications with Stakeholders
                                                                                                                                                                                                                                                Daily communication
The Company values communication with all stakeholder groups. Focusing on business operations and sustainability-related                                                                 Due diligence
                                                                                                                                                                                                                                                Of?ine meetings
topics, it continuously monitors reasonable expectations across stakeholder groups and engages through multiple channels.                                                                Environmental compliance management
                                                                                                                                                        Government and                                                                          Training participation
                                                                                                                                                                                         Rural revitalization
Feedback received serves as a key input for improving management and optimizing decision-making, supporting the Company's                             regulatory agencies                                                                       Information disclosure
stable operations and long-term development.
                                         Message            About             2025 Key                                                          Governance and Compliance                                             Green Operations to      Employee Development
                       About This                                                                       Sustainability                                                                    Product System for Value
                                         from the          Hapharm          Performance in                                      Special Topic   to Solidify a Foundation for                                          Advance Low-Carbon        to Build a Safe and     Appendix             2025 Sustainability Report
                        Report                                                                          Management                                                                                Creation
                                         Chairman           Group            Sustainability                                                            Stable Growth                                                     Management                Shared Future
Material Topic Matrix
                                                                                                                                                                         High
In advancing its sustainability management, the Company systematically identi?es sustainability-related challenges and opportu-
nities in its operations by considering key capital market concerns, national policy directions, industry trends, and its own strate-
gic priorities. On this basis, it has established and re?ned a materiality assessment mechanism for sustainability topics, evaluating
them along two dimensions—?nancial materiality and impact materiality—to determine priority levels. The assessment outcomes                                                                                                                                           Access to Medicines and
                                                                                                                                                                                                                                                                      Pharmaceutical Inclusiveness
serve as a critical basis for formulating management measures and optimizing decisions.                                                                                                                                         Customer rights and
                                                                                                                                                                                                                                interests protection
                                                                                                                                                                                                                                                                                         Safety and
                                                                                                                                                                                                                                               Responsible                               quality of
                                                                                                                                                                                                                                               marketing                                 products and
                                                                                                                                                                                                                                                                                         services
               Establishment of a                                                                                                                                                                                    Supply chain security
         ??    sustainability topic library                                                     ??    Stakeholder survey
                                                                                                                                                                                                                                              Pollutant
                                                                                                                                                                                                                                              emissions
                                                                                                                                                                                                            Corporate governance
                                                                                                                                                    Impact materiality
       Requirements from regulators,                                                          Distributing stakeholder survey                                                                                                               Internal control and
                                                                                                                                                                                                                      Contributions         risk management
       capital markets, and rating                                                            questionnaires;                                                                       Data security and customer        to the society               Industry cooperation               Employees
       agencies;                                                                                                                                                                    privacy protection                                             and exchange
                                                                                                                                                                                                             Anti-unfair competition
                                                                                              Gathering statistics on issues of                                                   Equal treatment to small and
                                                                                                                                                                                  medium-sized enterprises                                                                                Innovation-driven
       Macro-policy and industry standard                                                     concern to stakeholders;                                                                                                       Environmental compliance                                     development
       requirements;                                                                                                                                                                                                         management
                                                                                                                                                                                                                                    Communications with
                                                                                              Organizing focus group interviews.                                                                              Waste disposal        stakeholders
       Peer practices, company business
                                                         Company management                                                                                                                                                                 Anti-commercial bribery and
       practices, and characteristics.              ??   survey
                                                                                                                                                                                     Rural revitalization
                                                                                                                                                                                                                                            anti-corruption
                                                                                                                                                                                             Usage of water resources
                                                                                                                                                                                                                                            Energy usage
                                                                                                                                                                                                            Shareholder rights protection
                                                Distributing company management
                                                survey questionnaires;                                                                                                               Ecosystem and
                                                                                                                                                                                     biodiversity conservation                Due diligence
                                                                                                                                                                                                                                                                   Climate change tackling
                                                                                                                                                                                                                            Ethics of science and
                                                Analyzing the ?nancial impact of                                                                                                                                            technology                                                 Compliant operation
                                                sustainability topics;                                                                                                                                        Circular economy
                                                Organizing focus group interviews.
                                                                                                      Formation of a double                                                                                                                                                                          High
         ??    Materiality assessment                                                           ??    materiality matrix
                                                                                                                                                                                                                            Financial materiality
                                                                                                                                                                         Governance issues         Environmental issues            Social issues
       Assessing ?nancial materiality;                                                        Forming a double materiality matrix
                                                                                              to present the results of topic
       Assessing impact materiality;                                                          analysis and assessment;
       Determining the materiality                                                            The Board of Directors’ review of
       threshold.                                                                             the double materiality matrix.
                                        Message           About              2025 Key                                                       Governance and Compliance                                   Green Operations to    Employee Development
                     About This                                                                      Sustainability                                                        Product System for Value
                                        from the         Hapharm           Performance in                                   Special Topic   to Solidify a Foundation for                                Advance Low-Carbon      to Build a Safe and     Appendix               2025 Sustainability Report
                      Report                                                                         Management                                                                    Creation
                                        Chairman          Group             Sustainability                                                         Stable Growth                                           Management              Shared Future
             Special                                 Empowering with a Digital and Intelligent Engine, Building a Foundation
             Topic                                   for High-Quality Development Through Technological Innovation
Focused on enhancing production governance capabilities and quality control, the Company systematically advances digital
workshop construction, embedding digital technologies throughout production operations and quality management. It continu-
                                                                                                                                            Controlled Production and Quality Throughout the
ously strengthens a production management foundation characterized by controllable quality, visible processes, and traceable                Entire Process
data, establishing digital manufacturing practices that meet regulatory requirements and offer replicable value.
                                                                                                                                            In production process management, electronic batch records (EBR) serve as the core, enabling systematic recording and audit
                                                                                                                                            trail management of weighing, material charging, process parameters, and critical operational nodes. It mitigates risks arising from
                                                                                                                                            manual data entry and information dispersion, greatly improves data integrity and traceability, and effectively ensures stable and
                                                                                                                                            controlled production processes. Product quality data is synchronized with production data, allowing centralized analysis and
Uni?ed Architecture and System Integration                                                                                                  trend identi?cation through the quality management and analytics system. This supports deviation management, non-conforming
                                                                                                                                            product control, and continuous improvement, shifting quality management from post-event correction toward real-time process
                                                                                                                                            monitoring and proactive early warning, thereby continuously strengthening closed-loop quality issue management capabilities.
The oral liquid formulation workshop of Sanchine and the oral solid dosage form workshop of Hayao No.6 Factory are advancing
digital upgrades under a uni?ed technical architecture and management standards. Through coordinated system integration and
on-site retro?tting, they are progressively building a digital operations system covering production execution, quality control,
equipment operation, and energy management. At the system level, both workshops have uniformly deployed supervisory control
and data acquisition (SCADA) systems, with the manufacturing execution system (MES) as the core, interconnected with the
equipment asset management (EAM) system, warehouse management system (WMS), energy management system (EMS), and
quality retrospection and analysis system (QRS). This enables centralized collection and collaborative management of production,
quality, equipment, and energy consumption data, laying the groundwork for replication and scaled deployment across other
workshops.
                                                                                                                                                                  Digital production site at Sanchine                                    哈药六厂车间数字化生产现场
                                                                                                                                                                                                                              Digital production site at Hayao No.6 Factory workshop
               Digital Management System Platform                                   Digital Exhibition & Display Platform
                                        Message          About              2025 Key                                                      Governance and Compliance                                 Green Operations to   Employee Development
                    About This                                                                     Sustainability                                                        Product System for Value
                                        from the        Hapharm           Performance in                                  Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and    Appendix                   2025 Sustainability Report
                     Report                                                                        Management                                                                    Creation
                                        Chairman         Group             Sustainability                                                        Stable Growth                                         Management             Shared Future
           Special                                   Empowering with a Digital and Intelligent Engine, Building a Foundation
           Topic                                     for High-Quality Development Through Technological Innovation
Equipment Intelligence and Operational Ef?ciency                                                                                          Capability Building and Demonstration Effectiveness
Improvement
Hayao No.6 Factory continues to advance digital workshop construction through equipment con?guration and automation                       While ensuring stable system operations, the Company simultaneously advances digital capability building. Through internal
upgrades, introducing AGVs, collaborative robots, and automated production lines, and deploying intelligent equipment such as             training and hands-on practice, it cultivates versatile talent who understand both production processes and digital applications,
multi-functional ?uidized beds and high-speed tablet presses to drive the automation and standardization of key processes. A total        enhancing the system's self-operation and continuous optimization capabilities to ensure long-term, stable realization of digital
of 183 production units are under centralized monitoring, with a 90% connectivity rate for critical equipment. Operational data           outcomes. The relevant projects have received provincial-level digital workshop certi?cation and national Level 3 Intelligent Manu-
analysis has reduced unplanned downtime by approximately 30% and increased overall equipment effectiveness (OEE) by an                    facturing Capability Maturity certi?cation. While strengthening compliance management, these initiatives ensure process stability
average of 10.5%, signi?cantly improving equipment stability and resource utilization ef?ciency. Based on visualization tools such        and consistency through precise control and end-to-end traceability, fundamentally enhancing the quality and safety of ?nished
as the production cockpit, the real-time production status, quality metrics, and equipment performance are centrally displayed.           pharmaceutical products—a contribution of signi?cant importance to public medication safety and societal health.
Operational ef?ciency in key processes has improved by 10%–22%, material traceability time has been shortened by 40%–70%,
order changeover ef?ciency has increased by approximately 80%, inventory accuracy has reached 99.5%, and inventory backlog
risk has been reduced by about 25%.
Sanchine has introduced leading domestic oral dosage production equipment and, through ef?cient integration, achieved full-pro-
cess automation across washing, drying, ?lling, sterilization, visual inspection, and packaging. By implementing SCADA and MES
systems, it has enabled seamless data interconnectivity between equipment and systems, achieving a 100% connectivity rate for
critical equipment and establishing a robust foundation for production monitoring. Replacing manual material handling with an
integrated system of automated conveyance tracks, AGVs, and mobile terminals has increased on-time material delivery in
workshops to 98% and delivery accuracy to over 99.5%. Through a dynamic process optimization model, equipment OEE has
reached 80%, and on-time order delivery has improved by 13%. Additionally, energy collection and management systems have
enabled signi?cant energy savings in production, reducing energy consumption per RMB 10,000 of output value by 15.9%.
                                                                                                                                                             Certi?cate of Heilongjiang Province Advanced-Lev-                        Intelligent Manufacturing Capability
                                                                                                                                                                             el Digital Workshop                                        Maturity Assessment Certi?cate
              Digital workshop management platform                                   AGV logistics turnover at Sanchine
    Governance and
Compliance to Solidify
    a Foundation for
       Stable Growth
The content of this chapter
Party Building Leadership and Responsibility Implementation   ??
Construction of Corporate Governance System                   ??
Internal Control and Compliance Management                    ??
Culture of Integrity and Honest Operations                    ??
                                          Message               About               2025 Key                                                  Governance and Compliance                                 Green Operations to    Employee Development
                    About This                                                                              Sustainability                                                   Product System for Value
                                          from the             Hapharm            Performance in                              Special Topic   to Solidify a Foundation for                              Advance Low-Carbon      to Build a Safe and      Appendix   2025 Sustainability Report
                     Report                                                                                 Management                                                               Creation
                                          Chairman              Group              Sustainability                                                    Stable Growth                                         Management              Shared Future
Party Building Leadership and Responsibility                                                                                                  Party Building-Led Key Project Initiatives
Implementation                                                                                                                                The Company insists on leveraging Party building to guide synergistic industry-academia-research collaboration and talent
                                                                                                                                              system development, treating joint Party building as a vital linkage for advancing scienti?c innovation, technology transfer, and
The Company adheres to the leadership of the Party in guiding its reform, development and governance practices. Party building
                                                                                                                                              talent cultivation. Centered on actual enterprise needs and industrial demands, it fosters co-construction partnerships with
work is conducted in strict accordance with the Constitution of the Communist Party of China, Regulations on the Work of Primary
                                                                                                                                              primary-level Party organizations in universities and research institutes, promoting organizational co-building, resource sharing,
Organizations of State-owned Enterprises of the Communist Party of China, Regulations on the Election of Primary Organizations
                                                                                                                                              and mechanism alignment to seamlessly connect research capabilities, industrial platforms, and talent pipelines. Within the
of the Communist Party of China and other relevant rules. It continuously improves the operational mechanism of Party building
                                                                                                                                              framework of deep integration between Party work and core operations, the Company explores practical pathways where joint
within a standardized and institutionalized framework, and regards high-quality Party building as an important support for enhanc-
                                                                                                                                              Party building facilitates technological breakthroughs and collaborative mechanisms support talent development, gradually
ing corporate governance capacity and operational ef?ciency.
                                                                                                                                              forming a working model of Party-led, industry-academia-research-linked, and talent-synergized advancement—providing
Focusing on the integrated development and mutual promotion of                                                                                sustained support for high-quality development.
Party building and business operations, the Company integrates Party
building into the entire process of corporate governance, production,
operation, reform and development. It keeps transforming the political
and organizational advantages of the Party into governance ef?ciency                                                                                     Case        Party building-led practices in production ef?ciency improvement and lean management
and development momentum. In practice, relying on the Four Promo-
tions mechanism of Party building promoting R&D, production,                                                                                           Hayao No.6 Factory, targeting improved production ef?ciency and cost optimization, uses the "Party Branch
marketing and services, the Company embeds the functions of prima-                                                                                     Secretary Leads Projects" initiative as a key lever to deeply integrate Party building into production organization
ry Party organizations into core business links systematically. This                                                                                   and on-site management. Branch secretaries focus on critical areas—including solid dosage production, process
achieves full-chain coordination between Party building and business                                                                                   optimization, quality testing, warehouse management, and digital transformation—leading the establishment of
operations, improves the pertinence and effectiveness of Party                                                                                         breakthrough projects and organizing core Party members into dedicated teams. Through lean production
leadership, and provides solid support for the steady operation and                                                                                    management, process streamlining, and technological upgrades, they continuously address operational bottle-
sustainable development of the enterprise.                                                            Party Member Training                            necks. These projects have achieved phased progress in shortening production cycles, optimizing resource
                                                                                                                                                       allocation, enhancing equipment utilization, and advancing digital management, demonstrating the positive role
                                                                                                                                                       of Party leadership in driving production ef?ciency and management upgrades.
Party Building-Led Synergistic Development of Industry, Academia,
Research, and Talent
The Company insists on leveraging Party building to guide synergistic industry-academia-research collaboration and talent
system development, treating joint Party building as a vital linkage for advancing scienti?c innovation, technology transfer, and
talent cultivation. Centered on actual enterprise needs and industrial demands, it fosters co-construction partnerships with
primary-level Party organizations in universities and research institutes, promoting organizational co-building, resource sharing,
and mechanism alignment to seamlessly connect research capabilities, industrial platforms, and talent pipelines. Within the
framework of deep integration between Party work and core operations, the Company explores practical pathways where joint
Party building facilitates technological breakthroughs and collaborative mechanisms support talent development, gradually
forming a working model of Party-led, industry-academia-research-linked, and talent-synergized advancement—providing
sustained support for high-quality development.
                                                                                                                                                                                    Hayao No.6 Factory's "Party Branch Secretary Leads Projects" Initiative
                                 Award Ceremony for Inheriting the Scientists' Spirit and Advancing Innovation
                                      Message               About                2025 Key                                                 Governance and Compliance                                  Green Operations to   Employee Development
                   About This                                                                            Sustainability                                                  Product System for Value
                                      from the             Hapharm             Performance in                             Special Topic   to Solidify a Foundation for                               Advance Low-Carbon     to Build a Safe and    Appendix            2025 Sustainability Report
                    Report                                                                               Management                                                              Creation
                                      Chairman              Group               Sustainability                                                   Stable Growth                                          Management             Shared Future
                                                                                                                                          Construction of Corporate Governance System
                 Party building-led practices in cost reduction, ef?ciency enhancement, and production capacity
        Case     breakthroughs
     Sanjing Mingshui, focusing on key tasks such as cost control, expense reduction, and capacity enhancement,                           The Company strictly complies with the Company Law of the People's Republic of China, the Securities Law of the People's Repub-
     systematically advances the "Party Branch Secretary Leads Projects" special initiative. The Party Committee, aligned                 lic of China, and relevant regulatory requirements of the China Securities Regulatory Commission (CSRC) and stock exchanges.
     with operational realities, selects topics scienti?cally and initiates projects precisely. Branch secretaries serve as               It continuously enhances its corporate governance structure and internal governance systems, standardizes the operational
     primary project leaders, forming Party-member-led task forces and establishing mechanisms for planning, progress                     mechanisms of authority and responsibility, and ensures lawful and compliant operations. By strengthening the governance
     tracking, and scheduling to ensure orderly implementation. Projects target critical areas including API capacity                     framework comprising the Shareholders' Meeting, the Board of Directors and its specialized committees, and management level,
     expansion, process optimization, and energy system upgrades, achieving substantive progress in increasing batch                      the Company promotes scienti?c decision-making, standardized operations, and steady development, laying a solid governance
     output, optimizing production ef?ciency, and stabilizing product quality. By leading breakthrough projects through                   foundation for its sustainability.
     Party building, grassroots organizational vitality is further energized, providing strong support for the Company's
                                                                                                                                                                                            Shareholders' Meeting                                      Audit Committee
     achievement of annual business objectives.
                                                                                                                                                                                                                                              Strategy and Sustainability Committee
                                                                                                                                                                                              Board of Directors
                                                                                                                                                                                                                                              Remuneration and Appraisal Committee
                                                                                                                                                                                                    President
                                                                                                                                                                                                                                                    Nomination Committee
                                                                                                                                           Secretary         Chief              Vice                    Vice                   Vice                 Vice
                                                                                                                                           of the            Financial          President of            President of           President of         President of
                                                                                                                                           Board of          Of?cer             R&D                     Production             Marketing            Operations
                                 Sanjing Mingshui's "Party Branch Secretary Leads Projects" Initiative
                                                                                                                                           Directors
                                                                                                                                                                                                        Governance structure
        Case     Party building-led practices in technological breakthroughs and innovation
     Sanchine focuses on technological innovation and quality improvement, using the "Party Branch Secretary Leads
     Projects" initiative as a key vehicle to advance Party-building empowerment. It channels the strength of Party organi-
     zations toward the front lines of R&D and production. Each Party branch establishes task-force projects aligned with
     key priorities such as production process optimization, quality and cost control, and automation upgrades, and
     organizes Party-member technical experts to advance them collaboratively. Through measures including equipment
     parameter optimization, process ?ow improvements, and automation enhancements, these projects have achieved
     phased results in reducing production losses, increasing ?nished product yield, and advancing intelligent manufac-
     turing. The project-based approach under Party leadership has effectively fostered synergistic alignment between
     technological breakthroughs and business development.
                                                                                                                                                                                                      Management Group Photo
                                    Sanchine's "Party Branch Secretary Leads Projects" Initiative                                         Focusing on corporate governance and standardized operations, the Company has established and continuously improved its
                                                                                                                                          governance system and rules of procedure, including the Rules of Procedure for Shareholders' Meetings, the Rules of Procedure
                                                                                                                                          for the Board of Directors, the Independent Director System, and working rules for specialized committees. These institutional
                                                                                                                                          arrangements clearly de?ne the boundaries of authority and responsibility and operational mechanisms of governance bodies,
                                                                                                                                          providing an institutional guarantee for the independent and effective performance of the Board of Directors.
                                         Message            About              2025 Key                                                      Governance and Compliance                                  Green Operations to   Employee Development
                     About This                                                                     Sustainability                                                          Product System for Value
                                         from the          Hapharm           Performance in                                  Special Topic   to Solidify a Foundation for                               Advance Low-Carbon     to Build a Safe and    Appendix               2025 Sustainability Report
                      Report                                                                        Management                                                                      Creation
                                         Chairman           Group             Sustainability                                                        Stable Growth                                          Management             Shared Future
The Company has established a governance structure characterized by clear
delineation of powers and responsibilities, standardized operations, and mutual                                                                          During the reporting period, the Company
checks and balances. The Shareholders' Meeting, composed of all shareholders,
serves as the Company's governing authority and exercises decision-making
                                                                                                                                                                            Had independent directors                                      Had female directors
power over major corporate matters in accordance with the law. Through
standardized procedural rules, it ensures that all shareholders can exercise their                                                                                          accounting for   ??.?         %                                accounting for    ??.?       %
rights lawfully and equally. The Board of Directors is accountable to the Share-
holders' Meeting and ful?lls its statutory decision-making and supervisory
duties. Senior management personnel are appointed by the Board of Directors
and are responsible for the Company's day-to-day business operations and                            Annual General Meeting                   The Board of Directors ful?lls its statutory supervisory responsibilities regarding the Company's strategic planning, business
implementation of Board resolutions.
                                                                                                                                             management, and risk control. By convening board meetings regularly, it reviews key matters related to the Company's business
                                                                                                                                             development, ensuring that Board operations are standardized, orderly, and ef?cient. This guarantees compliance with
To safeguard the independence and effectiveness of the Board of Directors, the Company has implemented institutional arrange-
                                                                                                                                             decision-making procedures and truthful, accurate, and complete information disclosure, thereby effectively safeguarding the
ments such as the Independent Director System and the Working System for Special Meetings of Independent Directors. These
                                                                                                                                             Company's overall interests and the legitimate rights of all shareholders.
provide a mechanism to support independent directors in performing their duties lawfully, independently, and prudently, thereby
enhancing the Board's oversight and checks-and-balances capacity in decision-making on major matters and improving the
standardization and effectiveness of its overall operations.
                                                                                                                                                         During the reporting period, the Company
          Case      Special research to strengthen support for independent directors in ful?lling their duties
                                                                                                                                                         ??                                  ??                          Achieved a director                     Organized   ?   director
                                                                                                                                                                                                                                              ???
                                                                                                                                                  Held         Board of           at which         matters
        In July 2025, the Board of Directors' Of?ce of the Company organized a special research session for independent                                                                                                                                          training sessions
                                                                                                                                                  Directors meetings              were reviewed and approved             attendance rate of            %
        directors, featuring thematic reports and discussions on GNC China's business operations, marketing system
        development, strategy execution, and cross-border business expansion. Drawing on their industry experience and
        regulatory insights, the independent directors provided targeted recommendations on business operations and
        risk management. On-site engagement deepened their understanding of industrial chain operations and gover-
        nance practices.
        The    Company     continues   to   strengthen   independent                                                                         To further enhance the professionalism and scienti?c basis of Board decision-making, the Company's Board of Directors has
        directors' familiarity with key business areas and operational                                                                       established four specialized committees: the Audit Committee, the Strategy and Sustainability Committee, the Nomination
        processes through special research, joint business visits,                                                                           Committee, and the Remuneration and Appraisal Committee. Each committee carries out its duties according to de?ned responsi-
        performance-related training, and information exchange                                                                               bilities and provides support and recommendations to the Board on relevant professional matters, thereby promoting scienti?cally
        mechanisms, enabling more informed and targeted profes-                                                                              grounded decision-making and effective performance of duties.
        sional judgment in decision-making and oversight. These
        arrangements have gradually evolved into a regularized
        support mechanism for director duties, effectively enhanc-                                                                                       During the reporting
                                                                                                                                                                                                       During the reporting period, the Company was awarded
                                                                                                                                                         period, the Company
        ing information transparency and communication ef?ciency,
        and promoting more standardized, stable, and ef?cient
        corporate governance.
                                                                                                                                                  Held   ?   Audit Committee
                                                                                                                                                  meetings
Board Diversity                                                                                                                                   Held   ?   Strategy and
                                                                                                                                                  Sustainability
The Company speci?es in its Rules of Work for the Nomination Committee of the Board of Directors that, in the nomination and                      Committee meeting
appointment of directors, it comprehensively considers candidates' professional backgrounds, industry experience, performance
capabilities, and independence. Diversity is treated as a key criterion to continuously optimize the composition of the Board of
Directors and foster a structure that integrates diverse perspectives and complementary expertise.                                                Held   ?   Nomination
                                                                                                                                                  Committee meeting
As of the end of the reporting period, the Company's Board of Directors consisted of nine directors, including one employee repre-
sentative director, three independent directors, and four female directors. The Board exhibits a relatively diverse composition in
terms of gender, functional roles, and professional backgrounds, which helps introduce varied perspectives into the decision-mak-
                                                                                                                                                  Held   ?   Remuneration                       2025 Excellent Practice for
                                                                                                                                                                                                the Board of Directors of a
                                                                                                                                                                                                                               for the Board of Directors'
                                                                                                                                                                                                                                                             for Secretary of the Board
                                                                                                                                                  and Appraisal                                      Listed Company            Of?ce of a Listed Company     Performance Evaluation of
ing process, thereby enhancing the quality of deliberations and the scienti?c rigor of decisions.                                                 Committee meetings                                                                                             Listed Companies
                                        Message             About               2025 Key                                                            Governance and Compliance                                   Green Operations to   Employee Development
                      About This                                                                            Sustainability                                                           Product System for Value
                                        from the           Hapharm            Performance in                                        Special Topic   to Solidify a Foundation for                                Advance Low-Carbon     to Build a Safe and     Appendix              2025 Sustainability Report
                       Report                                                                               Management                                                                       Creation
                                        Chairman            Group              Sustainability                                                              Stable Growth                                           Management             Shared Future
                                                                                                                                                    The Company consistently focuses on protecting the rights of small and medium-sized investors—including their right to informa-
                                                                                                                                                    tion, right to participation, and other legitimate interests. By creating diverse and accessible communication scenarios, it advanc-
Investor Relations Management                                                                                                                       es investor relations management from one-way information dissemination toward two-way interaction, thereby deepening small
                                                                                                                                                    and medium-sized investors' understanding of and con?dence in the Company's governance and long-term value.
The Company places great importance on investor relations management, recognizing it as a critical component for enhancing
corporate governance transparency, strengthening market recognition, and protecting investors' legitimate rights and interests. It
has formulated and implemented the Investor Relations Management System and the Market Value Management System, which
clearly de?ne responsibilities, work?ows, and communication standards for investor relations activities, ensuring their lawful,
                                                                                                                                                                Case       Special research to strengthen support for independent directors in ful?lling their duties
compliant, and orderly execution.
                                                                                                                                                            In September 2025, the Company participated in the "I am
                                                                                                                                                            a Shareholder" event for listed companies organized by
                                                                                                                                                            the Shanghai Stock Exchange. In collaboration with the
                                                                                                                                                            China Association for Public Companies, the China
                Transparent information disclosure                                 Diversi?ed communication channels
                                                                                                                                                            Securities Investor Services Center, and the Shanghai
                                                                                                                                                            Securities News, it invited more than 20 small and
                                                                                                                                                            medium-sized investors for an on-site visit and exchange.
       Aligning with key capital market concerns—such as                  To ensure the stability and effectiveness of
                                                                                                                                                            During the event, investors toured the Sanchine exhibi-
       operating performance, development strategy, risk                  communication channels, the Company has estab-
                                                                                                                                                            tion center and the intelligent oral liquid production line,
       management, and sustainability—the Company                         lished   a   diversi?ed      and      regularized     investor
                                                                                                                                                            gaining direct insight into the Company's development
       maintains ongoing communication with investors                     communication mechanism. Leveraging its of?cial
                                                                                                                                                            journey, product portfolio, and achievements in intelligent
       and shareholders through multiple channels. It                     website, the Shanghai Stock Exchange's "SSE
                                                                                                                                                            manufacturing.         Face-to-face     discussions   enabled     a
       provides timely updates on its operational status,                 e-interaction"        platform,    the     investor   hotline,
                                                                                                                                                            deeper     understanding        of   the   Company's     strategic
       business layout, and development plans, while                      earnings calls, and Shareholders' Meetings, it
                                                                                                                                                            planning and operational status. The event also featured a
       actively soliciting market feedback and construc-                  provides investors with reliable and convenient                                                                                                             "I am a Shareholder" visits Shanghai-listed company—
                                                                                                                                                            dedicated investor education session titled "Know Your                                       Hapharm Group
       tive suggestions to enhance the transparency and                   access to corporate information and opportunities
                                                                                                                                                            Rights, Exercise Your Rights, Protect Your Rights," aimed
       comprehensibility of its disclosures.                              for interaction.
                                                                                                                                                            at enhancing small and medium-sized investors' aware-
                                                                                                                                                            ness of rights protection.
            During the reporting period, the Company                                                                                                            During the reporting period, the Company was awarded
               ?
       Disclosed       periodic announcements and    ??    ad-hoc announcements;
               ?
       Organized      roadshows and held communications with a total of     ??     institutional investors;
               ??
       Conducted           reverse roadshows, hosted   ??     securities ?rms and institutional investors, with a total                                                  Certi?cate of Excellent Practice for
                                                                                                                                                                          the 2024 Annual Report Earnings
       of   ???      participants;                                                                                                                                             Call of Listed Companies
       Received and answered a total of   ???        investor inquiries via the investor hotline;
       Received a total of   ???     questions from investors, with a response rate of     ??.??                %
                                            Message            About               2025 Key                                                     Governance and Compliance                                       Green Operations to       Employee Development
                       About This                                                                         Sustainability                                                          Product System for Value
                                            from the          Hapharm            Performance in                                 Special Topic   to Solidify a Foundation for                                    Advance Low-Carbon         to Build a Safe and         Appendix                  2025 Sustainability Report
                        Report                                                                            Management                                                                      Creation
                                            Chairman           Group              Sustainability                                                       Stable Growth                                               Management                 Shared Future
                                                                                                                                                Strategy
Internal Control and Compliance Management                                                                                                      Supported by its institutional framework, the Company integrates compliance requirements throughout the entire cycle of
The Company values internal control and compliant operations, continuously re?ning relevant systems and management mecha-                       decision-making, execution, and supervision, extending them to all departments, subsidiary enterprises, and employees. This
nisms. It embeds compliance requirements into all aspects of business management, steadily enhancing its level of standardized                  facilitates the transition of compliance management from system establishment to normalized operation. Additionally, from the
operations and risk prevention capabilities to support sustainable and stable development.                                                      perspectives of operational stability and long-term development, the Company systematically identi?es compliance-related risks
                                                                                                                                                and opportunities, using these insights to continuously re?ne management measures and optimize resource allocation.
                                                                                                                                                      Risk name1                      Speci?c description                      Time horizon2            Financial impact              Response measures
Compliant Operation
                                                                                                                                                                                                                                                       Increased costs               Establish a “Three Lines
                                                                                                                                                                               There are instances where compli-                                       related to non-com-           of Defense” compliance
Governance                                                                                                                                            Compliance
                                                                                                                                                                               ance requirements are not fully                 Medium and              pliance, penalty              management system and
                                                                                                                                                      management
                                                                                                                                                                               implemented during their embedding              long term               expenses, and                 strengthen enforcement
The Company regards lawful and compliant operations as a fundamental requirement for business management and employee                                 execution risk
                                                                                                                                                                               and execution in business processes                                     potential litigation          of policies and supervi-
conduct. Building upon national laws and regulations, it has established a compliance management system centered on the                                                                                                                                losses                        sory inspections
Compliance Management Measures of HARBIN PHARMACEUTICAL GROUP CO., LTD., supplemented by specialized policies and
operational guidelines. During the reporting period, the Company issued three new guidelines: Compliance Guidelines for Prevent-                                                                                                                       Elevated risk of              Regularly conduct
                                                                                                                                                                               n key areas such as fund security, tax
ing Commercial Bribery in the Pharmaceutical Sector, Advertising Compliance Guidelines, and Compliance Guidelines for                                                                                                                                  fund loss, higher             compliance risk
                                                                                                                                                      Compliance               handling, trade secrets, and personal
                                                                                                                                                                                                                                                       compliance costs,             identi?cation and
Livestreaming Marketing Activities, further strengthening institutional controls over key risks in the pharmaceutical ?eld.                           risks in key             information protection, risk identi?ca-         Medium-term
                                                                                                                                                                                                                                                       and increased                 assessment, and
                                                                                                                                                      areas                    tion is insuf?cient or controls are
                                                                                                                                                                                                                                                       potential compen-             formulate and implement
The Company has established a compliance management organizational system centered on the Compliance Committee and the                                                         inadequately implemented
                                                                                                                                                                                                                                                       sation expenses               risk response plans
Chief Compliance Of?cer, supported by a management mechanism featuring clearly de?ned responsibilities and coordinated
operations. It has implemented a compliance management framework based on the "three lines of defense," embedding compli-
                                                                                                                                                 Opportunity name                      Speci?c description                      Time horizon            Financial impact              Response measures
ance responsibilities across management levels and business processes to ensure effective implementation of compliance
requirements throughout the organization.                                                                                                                                                                                                                                          Embed compliance
                                                                                                                                                                               The compliance management system
                                                                                                                                                                                                                                                                                   requirements into the
                                                                                                                                                      Opportunity for          and processes are continuously                                          Reduced compli-
                                                                                                                                                                                                                                                                                   entire process of
                                                                                                                                                      management               improved, and the integration of                Medium and              ance costs and
                                                                                                                                                                                                                                                                                   decision-making, execu-
                                                       Compliance Committee                                                                           ef?ciency                compliance requirements into                    long term               decreased
                                                                                                                                                                                                                                                                                   tion, and supervision to
                                                                                                                                                      improvement              business processes is progressively                                     operational losses
                      Responsible for the organizational leadership and overall coordination of compliance                                                                                                                                                                         promote process standard-
                                                                                                                                                                               enhanced
                      management, holding regular meetings to study and decide on major compliance matters                                                                                                                                                                         ization
                      or propose recommendations, and to guide, supervise, and evaluate compliance manage-                                                                     Compliance risk identi?cation and                                                                   Continuously carry out risk
                                                                                                                                                                                                                                                       Reduced risk-relat-
                      ment activities.                                                                                                                Risk and cost            proactive management mechanisms                                                                     identi?cation, classi?ed
                                                                                                                                                                                                                               Medium and              ed losses and
                                                                                                                                                      control                  are gradually strengthened, and risk                                                                management, and the
                                                                                                                                                                                                                               long term               improved cash ?ow
                                                                                                                                                      opportunities            control capabilities are continuously                                                               development of response
                                                                                                                                                                                                                                                       stability
                                                                                                                                                                               enhanced                                                                                            plans
            First line of defense                         Second line of defense                           Third line of defense
           All departments of the                        Compliance Management
                                                                                                   Discipline inspection and supervision                      Case      Building a compliance assurance system to promote full-staff compliance practices
                                                                                                   agencies, and audit, supervision, and
                  Company                                      Department
                                                                                                       accountability departments                     Centered on the principle of "Compliance Escorting High-Quality Develop-
                                                                                                                                                      ment," the Company has established a "1-2-3-10+" compliance assurance
     Bear direct and primary responsi-             Responsible for organizing,                      Within their scope of authority,
                                                                                                                                                      system, anchored by the Compliance Management Measures and the Employ-
     bility for compliance management              coordinating, guiding, and supervis-             they supervise the implementation
                                                                                                                                                      ee Compliance Manual. It is supported by three checklists—covering compli-
     within their scope of duties and are          ing compliance management                        of compliance requirements,
                                                                                                                                                      ance obligations/risks, responsibilities of key positions, and key process
     responsible for daily compliance              activities, and providing compliance             investigate violations, and carry out
                                                                                                                                                      controls—and guidelines for priority areas such as anti-commercial bribery in
     management in their respective                support to other departments                     accountability procedures as
                                                                                                                                                      the pharmaceutical sector and advertising compliance, effectively embedding
     business areas or departments.                (subsidiary enterprises).                        stipulated.
                                                                                                                                                      compliance requirements into business processes.
                                                                                                                                                      Through mechanisms such as compliance reviews, risk early-warning systems,
                                                                                                                                                      and violation reporting channels, the Company achieves comprehensive cover-
         Compliance Administrator                  Compliance Management Specialist                     Compliance Administrator                                                                                                                                   "1-2-3-10+" compliance assurance
                                                                                                                                                      age across its 18 subsidiary enterprises, transitioning compliance from institu-                                          system
                                                                                                                                                      tional design to daily execution and employee practice. This provides
                Compliance administrators receive business guidance and training from the compliance management
                                                                                                                                                      sustained assurance for stable operations.
                department and provide compliance advice to their department heads for decision-making reference.
                                      Organizational structure of Hapharm Group compliance management
                                                                                                                                                    The risks and opportunities listed in this table are forward-looking identi?cations made by the Company based on changes in external environment and
                                                                                                                                                  internal operational conditions. They are intended to re?ect the potential impact trends and key management priorities, and shall not constitute a de?nitive
                                                                                                                                                  judgment on future events, nor indicate that relevant risks have materialized or exerted signi?cant impacts on the Company’s current operations.
                                                                                                                                                    Impact time refers to the timeframe over which a signi?cant impact is exerted on the Company: short-term—within 1 year; medium-term—1 to 5 years;
                                      Message           About               2025 Key                                                    Governance and Compliance                                 Green Operations to     Employee Development
                   About This                                                                        Sustainability                                                    Product System for Value
                                      from the         Hapharm            Performance in                                Special Topic   to Solidify a Foundation for                              Advance Low-Carbon       to Build a Safe and   Appendix           2025 Sustainability Report
                    Report                                                                           Management                                                                Creation
                                      Chairman          Group              Sustainability                                                      Stable Growth                                         Management               Shared Future
Focusing on the compliance management goals of "comprehensive coverage, ef?cient operation, controllable risks, and cultural
consciousness," the Company continuously improves its compliance management system supported by organization, systems,
                                                                                                                                        Impact, risk, and opportunity management
operations, and assurance, embedding compliance requirements into the entire process of business management and employee                Focusing on the goal of lawful and compliant operations, the Company embeds the identi?cation and management of compli-
performance. By compiling and issuing the Employee Compliance Manual and organizing all employees to sign the Compliance                ance-related impacts, risks, and opportunities into the entire process of business management. It achieves uni?ed management
Commitment Letter, it clari?es employee compliance obligations and behavioral boundaries.                                               through system development, process control, and supervisory collaboration. Relying on the Compliance Committee, the Chief
                                                                                                                                        Compliance Of?cer, and relevant functional departments, and in conjunction with actual business operations, it continuously
The Company upholds the compliance culture philosophy of
                                                                                                                                        identi?es potential compliance risks and their potential impacts in key areas such as fund security, tax management, trade secret
"acting within principles and rules; with reverence and
                                                                                                                                        protection, and personal information protection. It then conducts a graded assessment based on the likelihood and impact of
self-restraint," and promotes the building of a compliance
                                                                                                                                        these risks. For the identi?ed key risks, the Company clari?es management responsibilities through a "three lines of defense"
culture through a combination of training and advocacy.
Relying on its annual compliance training plan, it conducts                                 ???     % signing rate for the
                                                                                            Compliance Commitment Letter
                                                                                                                                        mechanism, promoting the effective implementation of risk response measures in system execution, daily supervision, and recti?-
                                                                                                                                        cation. Through continuous tracking and dynamic assessment, it constantly optimizes its compliance management system, releas-
compliance education for key positions and new employees,
                                                                                                                                        ing potential opportunities such as improved management ef?ciency and risk cost control while preventing risks.
covering topics such as anti-commercial bribery, business
compliance, and professional conduct. Through diversi?ed
advocacy formats, it strengthens warning and guidance,                                                                                  Indicators and objectives
continuously enhancing employees' compliance awareness.
                                                                                                                                        The Company takes enhancing the effectiveness of compliance management and the level of compliance risk prevention and
                                                                                                                                        control as the core goal of its compliance management. By improving the compliance management system, it reduces the proba-
                                                                                                                                        bility of major compliance risks, ensures that business activities are conducted in accordance with laws and regulations, and
         Case     Building legal and compliance capabilities in key business areas                                                      safeguards its operational stability and long-term development foundation.
       In June 2025, the Company organized a special topic lecture on business legal compliance, focusing on key
       business areas such as distributor management and live-streaming operations. An external team of professional
                                                                                                                                                                 Indicator name                                         Unit                                ????
       lawyers was invited to deliver the lecture. The training focused on distribution and agency contract management,                     Number of compliance risks identi?ed during the year                        Items                                156
       rebate and third-party expense control, legal risks in online live-streaming promotion, and vertical monopoly
       compliance requirements. A total of 249 employees participated online and of?ine. Through special topic explana-                     Number of compliance risk response plans formulated                     Copies                                   15
       tions and case analyses, participants further identi?ed compliance risk points in their business operations and
                                                                                                                                              Number of compliance training sessions conducted                          Times                                 5
       enhanced their contract management and risk prevention capabilities.
                                                                                                                                            Number of employees covered by compliance training                   Person-times                               1,010
                                                                                                                                        Internal Control
                                                                                                                                        The Company continuously improves its internal control management system, regarding internal control as an important founda-
                                                                                                                                        tion for standardizing business management, preventing operational risks, and enhancing governance effectiveness. Under the
                                                                                                                                        supervision and guidance of the Board of Directors and its Audit Committee, management coordinates and promotes work related
                                                                                                                                        to internal control and internal audit, pushing for internal control requirements to cover the entire process of decision-making,
                                                                                                                                        execution, and supervision, and ensuring their implementation throughout the Company and its subsidiaries.
                                                                                                                                        The Company has established and operates an internal control evaluation mechanism, where management organizes and
                                                                                                                                        conducts self-assessments of internal control to systematically evaluate the design and execution effectiveness of its systems.
                                                                                                                                        Combined with the results of internal supervision and external independent audits, it continuously examines the operation of
                                                                                                                                        internal controls.
                                                                                                                                        The Company formulates an annual internal audit plan to audit the business management and internal control operations of the
                                                                                                                                        Company and its subsidiaries. It also promotes the recti?cation and implementation of issues found during audits, forming a
                                                                                                                                        closed-loop management system. During the reporting period, the Company conducted 19 internal audit projects covering key
                                                                                                                                        business processes such as procurement, marketing, fund usage, engineering projects, asset management, ?nancial accounting,
                                                                                                                                        budget execution, and contract management. No major issues were found.
                                                  Compliance Training Session
                                           Message         About               2025 Key                                                      Governance and Compliance                                       Green Operations to      Employee Development
                     About This                                                                      Sustainability                                                             Product System for Value
                                           from the       Hapharm            Performance in                                  Special Topic   to Solidify a Foundation for                                    Advance Low-Carbon        to Build a Safe and      Appendix                 2025 Sustainability Report
                      Report                                                                         Management                                                                         Creation
                                           Chairman        Group              Sustainability                                                        Stable Growth                                               Management                Shared Future
Culture of Integrity and Honest Operations                                                                                                   Anti-Unfair Competition
The Company adheres to lawful, compliant, and honest operations, making integrity building an important part of its corporate                Focusing on anti-monopoly and anti-unfair competition management, the Company strictly implements the requirements of laws
governance and compliance management. It continuously improves its working mechanisms for anti-commercial bribery, anti-cor-                 and regulations such as the Anti-Monopoly Law of the People's Republic of China and the Anti-Unfair Competition Law of the
ruption, anti-monopoly, and anti-unfair competition, as well as for building an integrity culture and protecting whistleblowers. It          People's Republic of China. In conjunction with the Company's and the sector's business characteristics, it has formulated and
promotes the integration of integrity requirements into its business management and the entire process of employee perfor-                   implemented the Anti-Monopoly Management Regulations, integrating the principle of fair competition into its business manage-
mance, fostering a fair, transparent, and standardized business environment.                                                                 ment and employee performance standards. The Company re?nes and adopts relevant legal requirements through institutionalized
                                                                                                                                             means, clari?es internal management requirements, and promotes the enforceability and operability of anti-monopoly and
                                                                                                                                             anti-unfair competition requirements within the Company.
Anti-Commercial Bribery and Anti-Corruption
Focusing on anti-commercial bribery and anti-corruption management, the Company strictly implements the requirements of
                                                                                                                                             Whistleblower Protection
relevant laws and regulations such as the Criminal Law of the People's Republic of China and the Anti-Unfair Competition Law of
the People's Republic of China. In conjunction with its actual business management, it has formulated and implemented the
                                                                                                                                             The Company attaches great importance to the protection of the legitimate rights and interests of whistleblowers, making
Anti-Commercial Bribery Management Measures, which clarify the behavioral boundaries for employees in business dealings and
                                                                                                                                             whistleblower protection an important component of its integrity building and internal supervision mechanism. The Company has
in the course of their duties, and integrate integrity requirements into the Company's business management and employee perfor-
                                                                                                                                             clari?ed con?dentiality requirements for reported information at the institutional level and strictly implements the Provisions on
mance standards.
                                                                                                                                             Con?dentiality in Case Handling by the Discipline Inspection Commission of Harbin Pharmaceutical Group Holding Co., Ltd 1. It
                                                                                                                                             rigorously manages whistleblowing clues, the identity of whistleblowers, and related information to prevent leaks or improper use.
                      Reporting Mechanism                                                Integrity Commitment Letter                         he Company prohibits any form of retaliation and promptly addresses and handles any potential adverse effects arising from
  The Company has established and operates a reporting mecha-             In accordance with the uni?ed arrangements of the Group’s          whistleblowing activities. It strives to create a favorable environment where supervision is encouraged and conducted in accor-
  nism for commercial bribery and corruption, encouraging                 Discipline Inspection Commission, the Company organized            dance with the law, providing institutional guarantees for integrity building.
  employees and relevant parties to report violation clues in             all management personnel to sign the Commitment to
  accordance with laws and regulations. It has also set up                Integrity in Practice, achieving a 100% signing rate. For
  dedicated channels such as a telephone line and an email
  address to receive reports related to commercial bribery and
                                                                          con?rmed cases of commercial bribery and corruption, the
                                                                          Company conducts investigations and handles them in
                                                                                                                                             Integrity Culture Building
  corruption.                                                             accordance with the law and regulations, based on relevant
                                                                                                                                             The building of a culture of integrity continues to be synergistically advanced with the building of corporate culture. Through a
                                                                          provisions such as the Regulations on Disciplinary Actions
                Reporting hotline: ????????-?????                                                                                            combination of institutional guidance, publicity and education, and practical activities, the Company guides the integration of
                                                                          by the Communist Party of the People's Republic of China. It
                                                                                                                                             integrity requirements into employees' daily work and codes of conduct.
                                                                          holds the relevant parties seriously accountable to maintain
                Reporting email: hyjtjw@???.com                           a standardized and orderly business environment.
                                                                                                                                                    Relying on platforms such as the discipline enforcement and supervision section of its WeChat of?cial account, bulletin
         During the reporting period, the Company                                                                                                   boards, and electronic screens, the Company conducts regular publicity on integrity and compliance. It sets up special
                                                                                                                                                    topics such as interpretations of Party discipline and regulations and building of an integrity culture, gradually forming a
                                                                                                                                                    stable platform for disseminating the culture of integrity. During the reporting period, a total of 86 related articles were
                                                                                                                                                    published, with nearly 10,000 views. In conjunction with actual business management and the characteristics of key
                                                                                                                                                    positions, the Company conducts multi-level warning education. Through visits to integrity education bases, holding
                                                                                                                                                    warning education meetings, and using cases to explain discipline and law, it guides employees to be reverent and adhere
                                                                                                                                                    to the bottom line. During the reporting period, Party organizations and discipline inspection agencies at all levels
                                                                                                                                                    organized more than 90 warning education activities, covering over 6,300 participants. At the same time, through activi-
                                                                                                                                                    ties such as integrity-themed essay contests, short video creation, and integrity-focused home visits, the culture of
                Achieved   ???         %              Conducted     ??                          Organized   ?,???                                   integrity is extended to employees' work and life scenarios, promoting the transformation of integrity concepts from
                                                                                                                                                    institutional constraints to inherent self-discipline, and creating a favorable environment for stable operations.
                integrity risk assessment             anti-commercial bribery                   person-times of anti-com-
                coverage for the Company              and anti-corruption                       mercial bribery and
                and its subsidiaries                  training sessions                         anti-corruption training for
                                                                                                its employees
                                                                                                                                                 The Company’s discipline inspection, supervision, and Party committee-related functions are centrally managed by or implemented with reference to
                                                                                                                                             the Group, without affecting the effective operation of the Company’s governance structure and internal oversight mechanisms.
      Product System
    for Value Creation
The content of this chapter
Technological R&D and Innovation Practices            ??
Indicators and Objectives                             ??
Industrial Cooperation and Exchange                   ??
Product Quality and Safety Management                 ??
Customer Rights and Interests and Service Assurance   ??
Supply Chain Management and Security                  ??
Information Security and Privacy Protection           ??
Medication Accessibility Enhancement                  ??
                                             Message               About              2025 Key                                                          Governance and Compliance                                    Green Operations to   Employee Development
                        About This                                                                            Sustainability                                                              Product System for Value
                                             from the             Hapharm           Performance in                                      Special Topic   to Solidify a Foundation for                                 Advance Low-Carbon     to Build a Safe and   Appendix              2025 Sustainability Report
                         Report                                                                               Management                                                                          Creation
                                             Chairman              Group             Sustainability                                                            Stable Growth                                            Management             Shared Future
                                                                                                                                                         Opportunity name                      Speci?c description                Time horizon        Financial impact        Response measures
Technological R&D and Innovation-Driven Development                                                                                                                                                                                                                          Continuously to shift its
                                                                                                                                                                                                                                                                             R&D model from "imita-
                                                                                                                                                                                                                                                                             tion-innovation integra-
Governance                                                                                                                                               Development
                                                                                                                                                                                       Against the backdrop of innova-
                                                                                                                                                                                                                                                    Increased revenue,
                                                                                                                                                                                                                                                                             tion, imitation-oriented" to
                                                                                                                                                                                       tion-driven pharmaceutical develop-                                                   "imitation-innovation
                                                                                                                                                         opportunities for                                                         Medium and       higher gross margin,
The Company continuously optimizes its R&D management system, implementing uni?ed management and hierarchical advance-                                                                 ment, the company continues to                                                        integration, innovation-ori-
                                                                                                                                                         innovative drugs and                                                      long term        and enhanced asset
ment for R&D activities, and has formed an R&D organizational structure of "one department and ?ve institutes" to carry out this                                                       advance its R&D portfolio of innova-                                                  ented", and strengthens
                                                                                                                                                         improved new drugs                                                                         value
approach.                                                                                                                                                                              tive drugs and improved new drugs                                                     project initiation and R&D
                                                                                                                                                                                                                                                                             investment in innovative
The Company has established a Scienti?c Research Management Department responsible for the overall coordination, organiza-                                                                                                                                                   drugs and improved new
                                                                                                                                                                                                                                                                             drugs.
tion, and management of R&D work. Under its uni?ed management, ?ve specialized research institutes have been set up: the
Hapharm Drug Research Institute, Hapharm New Drug Research Institute, Hapharm Wellness Research Institute, Hapharm Biologi-
                                                                                                                                                                                                                                                                             Promote the systematic
cal Research Institute, and Hapharm Traditional Chinese Medicine Research Institute. These institutes respectively carry out R&D
                                                                                                                                                                                       The secondary development of                                                          research and secondary
work in the ?elds of generic drugs, innovative drugs, OTC and health products, biological products, and traditional Chinese                              Opportunities for the
                                                                                                                                                                                       established traditional Chinese                                                       development of
medicine. By clarifying management levels and responsibilities, the Company achieves integrated allocation and specialized                               secondary develop-                                                                         Enhanced value of
                                                                                                                                                                                       medicine (TCM) products is ongoing,                                                   established traditional
                                                                                                                                                         ment of established                                                       Medium-term      existing assets and
collaboration of R&D resources, promoting the orderly conduct of R&D activities within a uni?ed management framework.                                                                  continuously extending product life                                                   Chinese medicine
                                                                                                                                                         traditional Chinese                                                                        increased revenue
                                                                                                                                                                                       cycles and expanding application                                                      products, and continuous-
                                                                                                                                                         medicine products
                                                                                                                                                                                       value                                                                                 ly optimize the product
Strategy                                                                                                                                                                                                                                                                     pipeline structure
                                                                                                                                                        Construction of the R&D System
In accordance with overall development planning and R&D strategy, the Compa-
ny adheres to innovation orientation. With the core goals of enriching and
building product echelons, and optimizing R&D system and team, it continues to
                                                                                                                                                        The Company focuses on ?ve major disease areas: cardiovascular and cerebrovascular, digestive and metabolic, respiratory,
transform the R&D model from "imitation-innovation integration, imitation-ori-
                                                                                                                                                        anti-infective, and anti-tumor, as well as three key directions: geriatric medicine, pediatric medicine, and health products. It has
ented" to "imitation-innovation integration, innovation-oriented". Focusing on
                                                                                                                                                        built an product system featuring the coordinated advancement of chemical drugs, traditional Chinese medicine, and biological
key R&D ?elds, the Company keeps improving its R&D and technological innova-
                                                                                                                                                        drugs, supplemented by differentiated health products. The R&D project initiation focuses on generic drugs with high technical
tion system, and implements its ?ve-year R&D strategy and action plan. With the
                                                                                                                                                        barriers and innovative drugs, while simultaneously promoting the secondary development of established traditional Chinese
vision of building a century-old enterprise with sustainable sound development
                                                                                                                                                        medicine varieties with clinical value, continuously optimizing the product pipeline structure, and cultivating a competitive product
and becoming a benchmark in China’s pharmaceutical and health industry, the
                                                                                                                                                        echelon.
Company establishes long-term R&D thinking, making R&D an important
                                                                                                                                                        In terms of platform and capability building, the Company continuously
foundation supporting its high-quality development. During the implementation
                                                                                                                                                        improves its technology platform system adapted to its own R&D charac-
of R&D and innovation strategy, the Company identi?es and analyzes major risks                                                                                                                                                                              During the reporting period
                                                                                                                                                        teristics. It introduces key technological paths such as continuous ?ow,
and potential opportunities related to R&D, and takes corresponding counter-                              R&D Strategy Promotion Conference             biosynthesis, peptide synthesis, taste-masking technology, and sustained
measures.
                                                                                                                                                        and controlled release to enhance R&D ef?ciency and product differentia-                       Shiyitang Traditional Chinese Medicine
                                                                                                                                                        tion. At the same time, it regards the cultivation of scienti?c research                       has been successively accredited as
     Risk name                       Speci?c description                Time horizon          Financial impact           Response measures              talent as an important support for the R&D system. Through a combina-                          municipal and provincial Postdoctoral
                                                                                                                                                        tion of project practice, platform construction, external training, and                        Innovation Practice Base.
                                                                                                                                                        academic exchanges, it promotes R&D-production synergy and technolo-
                                                                                                                      Rationally allocate R&D
                                                                                           Increased R&D invest-                                        gy inheritance, solidifying the long-term foundation for R&D development.
                           The new drug R&D process involves a                                                        resources, advance R&D
 Risks related to the                                                                      ment and greater
                           long development cycle, technical            Medium and                                    projects in stages, and
 new drug R&D cycle                                                                        uncertainty in the
                           complexity, and uncertainty in interim       long term                                     strengthen dynamic                                       Jointly building the Cold Region Traditional Chinese Medicine R&D Platform to solidify the foundation of
 and uncertainty
                           outcomes
                                                                                           recovery of capitalized
                                                                                                                      management of R&D                            Case        industrial innovation
                                                                                           expenditures
                                                                                                                      projects
                                                                                                                                                                To advance the resource protection and modernization of Chinese materia medica in cold regions, Shiyitang Chinese
                                                                                                                                                                Medicine and Northeast Forestry University signed the Letter of Intent for the Construction of a Joint R&D Center for
                                                                                                                      Strengthen the evaluation
                                                                                                                                                                Cold-Region Longjiang Medicines, to jointly build the "Joint R&D Center for Cold-Region Longjiang Medicines" and,
 Risk of intensi?ed                                                                                                   of R&D project initiation,
                          In the high-barrier generic drug                                                                                                      on this basis, jointly establish a postdoctoral research workstation.
 competition for                                                                           Declining revenue and      focus on selecting
                          segment, market competition is
 generic drugs with                                                     Medium-term        compressed pro?t           varieties with technical
                          intensifying and pressure on R&D and                                                                                                  The two parties will cooperate in areas such as resource protection of authentic Chinese materia medica in cold
 high technical                                                                            margins                    barriers, and enhance R&D
                          regulatory registration is increasing                                                                                                 regions, GAP standardized planting, construction of a quality traceability system, and research on new functions and
 barriers                                                                                                             ef?ciency and product
                                                                                                                      differentiation                           components of traditional Chinese medicine. The initial cooperation period is planned for 2025–2029, aiming to
                                                                                                                                                                promote the transformation of scienti?c research achievements and the cultivation of professional talent, thereby
                                                                                                                                                                boosting the innovation capabilities and scienti?c research level of the regional traditional Chinese medicine industry.
                                                Message                    About               2025 Key                                                             Governance and Compliance                                    Green Operations to     Employee Development
                        About This                                                                                        Sustainability                                                           Product System for Value
                                                from the                  Hapharm            Performance in                                         Special Topic   to Solidify a Foundation for                                 Advance Low-Carbon       to Build a Safe and   Appendix        2025 Sustainability Report
                         Report                                                                                           Management                                                                       Creation
                                                Chairman                   Group              Sustainability                                                               Stable Growth                                            Management               Shared Future
                       Deepening industry-academia-research cooperation to promote the building of TCM innovation capabili-
                                                                                                                                                                    Green R&D and Green Products
         Case          ties
       In 2025, focusing on the innovative development of traditional Chinese                                                                                       The Company integrates green concepts into the entire R&D process, practicing the R&D policy of "green R&D + safety and
       medicine, Shiyitang Chinese Medicine organized its R&D team to conduct                                                                                       quality." Focusing on reducing energy consumption, minimizing pollution, and enhancing resource utilization ef?ciency, it continu-
       exchanges and investigations with universities including Harbin Institute                                                                                    ously promotes the application of green technologies in the R&D of pharmaceuticals and health products. Through technological
       of Technology, Beijing University of Chinese Medicine, Heilongjiang                                                                                          paths such as synthetic biology and continuous ?ow, the Company optimizes process ?ows at the R&D stage, reducing raw materi-
       University of Chinese Medicine, and scienti?c research institutions such                                                                                     al consumption and environmental load while improving reaction ef?ciency and product stability.
       as Tianjin Pharmaceutical Research Institute. Special seminars were held
       on innovative TCM drugs, improved TCM drugs, evidence-based medicine                                                                                         In speci?c practice, synthetic biology technology, centered on biological systems, achieves sustainable raw material conversion
       research and post-marketing evaluation of TCM injections.                                                                                                    and highly selective synthesis; continuous ?ow technology, centered on process intensi?cation, enhances the safety, stability, and
                                                                                                                                                                    resource utilization of reaction processes. These green technologies play a supporting role in the R&D and process design stages,
       Through sustained industry-university-research exchanges, the Company                                                                                        laying the foundation for the industrial application of green processes and driving product R&D towards low energy consumption,
       reached cooperation consensus on multiple research ?elds and promoted                                                                                        low emissions, and high quality.
       the signing of letters of intent. This laid a foundation for subsequent R&D                                                                                                                                                                                              Back Pressure
                                                                                                                Exchange Visit with Tianjin Pharmaceutical                                Delivery Unit                Mixing Unit                     Reaction Unit
       cooperation and achievement transformation, and further improved the                                                Research Institute                                                                                                                                       Unit
       enterprise’s innovation capacity and R&D system construction.
                                                                                                                                                                       Reagent
                                                                                                                                                                          A
                                                                                                                                                                                                                                                                                                   Product
The Company simultaneously improves its incentive and project management mechanisms for R&D personnel. It has formulated
and implemented the R&D Project Incentive Plan of HARBIN PHARMACEUTICAL GROUP CO., LTD. (Trial). Centered on the full                                                  Reagent
life-cycle management of R&D projects, this plan links project progress with the performance of R&D teams by setting quantitative                                         B
assessment indicators at key milestone nodes. This forms an achievement-oriented incentive mechanism, enhancing the motiva-                                                                                                   Continuous Flow Schematic Diagram
tion of R&D personnel and the ef?ciency of project execution, and providing a dynamic guarantee for the continuous advancement
of the R&D strategy.                                                                                                                                                Intellectual Property Protection
The Company continues to increase its R&D investment, supporting the implementation of its R&D strategy with an institutional-
ized investment guarantee mechanism. It advances projects through a combination of independent R&D and external cooperation.                                        The Company conducts intellectual property management in accordance with the law, strictly adhering to the requirements of laws
During the reporting period, over a hundred projects were initiated, covering new drugs, generic drugs, and biological products,                                    and regulations such as the Civil Code of the People's Republic of China, the Trademark Law of the People's Republic of China,
with more than 50 projects having been approved or completed. The Company and its subsidiaries have obtained multiple national,                                     and the Patent Law of the People's Republic of China, to implement full-process management of trademarks, patents, and
provincial, and municipal innovation quali?cations and have been recognized as scienti?c research platforms, providing support                                      copyrights. The Company has formulated and implemented the Regulations on the Management of Patents and Monographs to
for the implementation of the R&D strategy and the transformation of its achievements.                                                                              standardize matters such as application, maintenance, rights management, and termination. In terms of trademark management,
                                                                                                                                                                    it has implemented the Regulations on the Management of Trademarks of HARBIN PHARMACEUTICAL GROUP CO., LTD., clarifying
                                                                                                                                                                    the requirements for trademark registration, use, licensing, and maintenance to prevent infringement and improper use risks.
        Certi?cations/honors
                                                                                                                                                                    On the basis of system implementation, the Company enhances its intellectual property protection capabilities through training
          National High-tech Enterprise
                                                                                                                                                                    and exchanges. It conducts training for R&D personnel, new employees, and relevant positions on topics such as patent basics,
          HARBIN PHARMACEUTICAL GROUP CO., LTD.,
                                                                              National     Intellectual        Property     Advantage       Enterprise
                                                                                                                                                                    innovation point mining, rights protection practices, and standardized trademark use. It also organizes participation in sector
          Harbin Pharmaceutical Group Sanjing Qianhe Pharmaceu-
                                                                              (Demonstration)
                                                                                                                                                                    intellectual property exchange activities to continuously strengthen employees' compliance awareness and professional capabili-
          tical Co., Ltd.,                                                    Harbin Pharmaceutical Group Bioengineering Co., Ltd.                                  ties, promoting the effective protection and transformation of innovative achievements.
          Harbin Pharm Group Sanjing Pharmaceutical Co., Ltd.,
                                                                              Heilongjiang Province "Specialized, Re?ned, Differential,
          Harbin Pharmaceutical Group Bioengineering Co., Ltd.,
                                                                              and Innovative" Small and Medium-Sized Enterprise                                     Impact, Risks, and Opportunities
          Harbin Pharmaceutical Group Sanjing Mingshui Pharma-
                                                                              Harbin Pharmaceutical Group Bioengineering Co., Ltd.,
          ceutical Co., Ltd.,
                                                                              Harbin Shiyitang Chinese Medicine Co., Ltd.                                           In R&D activities, the Company simultaneously identi?es operational impacts, risks and development opportunities brought by
          Harbin Shiyitang Chinese Medicine Co., Ltd.,
          Harbin   Pharmaceutical      Group   Sanjing   Daqing   Glass       Heilongjiang Province Technological Innovation Demon-                                 technological innovation, and integrates relevant management requirements into R&D decision-making and project management
          Industrial Park Co., Ltd.,                                          stration Enterprise                                                                   processes. At key links including R&D project initiation, project evaluation and annual planning, the Company comprehensively
          Harbin Pharmaceutical Group Shiyitang Chinese Decoction                                                                                                   considers technical feasibility, market demand, policy environment and resource allocation. It systematically identi?es and assess-
                                                                              Harbin Pharmaceutical Group Bioengineering Co., Ltd.
          Pieces Co., Ltd.                                                                                                                                          es the uncertainty of cost, cycle and achievement in R&D activities.
          National Torch Program Harbin Antibiotic                            Heilongjiang Provincial Enterprise Technology Center                                  Via milestone management, phased evaluation and dynamic adjustment mechanisms, the Company maintains continuous supervi-
          Specialty Industrial Base                                           Harbin Pharmaceutical Group Bioengineering Co., Ltd.,                                 sion over R&D projects, and optimizes R&D pipeline and resource allocation based on evaluation results. While preventing R&D
          HARBIN PHARMACEUTICAL GROUP CO., LTD.                               HARBIN PHARMACEUTICAL GROUP CO., LTD.                                                 risks and improving resource ef?ciency, it promotes the transformation of technological innovation achievements, and sustains
                                                                                                                                                                    the supporting effect of innovation on core competitiveness and long-term development.
                                         Message             About              2025 Key                                                         Governance and Compliance                                   Green Operations to    Employee Development
                     About This                                                                       Sustainability                                                             Product System for Value
                                         from the           Hapharm           Performance in                                     Special Topic   to Solidify a Foundation for                                Advance Low-Carbon      to Build a Safe and      Appendix                 2025 Sustainability Report
                      Report                                                                          Management                                                                         Creation
                                         Chairman            Group             Sustainability                                                           Stable Growth                                           Management              Shared Future
Indicators and Objectives                                                                                                                        Industrial Cooperation and Exchange
Focusing on R&D and innovation work, the Company has de?ned its core management objective as improving the operational
                                                                                                                                                 Grounded in the broader context of the pharmaceutical and health industry's development, the Company actively integrates into
quality of the R&D system and the ef?ciency of achievement transformation. By strengthening the overall planning of R&D, project
                                                                                                                                                 the collaborative development patterns of the industrial and innovation chains. Focusing on key directions such as the inheritance
screening, and process management, it continuously optimizes the structure of the R&D pipeline and the ef?ciency of resource
                                                                                                                                                 and innovation of traditional Chinese medicine, the enhancement of fundamental industrial capabilities, and the transformation of
allocation. The Company focuses on strengthening the layout and management of projects with high technical barriers and high
                                                                                                                                                 scienti?c and technological achievements, it continuously expands the depth and breadth of industrial cooperation. This promotes
clinical value, promoting a positive cycle between R&D investment and product outcomes and business bene?ts, thereby provid-
                                                                                                                                                 the effective connection of industry, academia, research, and application, contributing to the overall improvement of the industrial
ing sustained support for the Company's long-term and steady development.
                                                                                                                                                 chain and the high-quality development of the regional pharmaceutical industry.
                           Indicator name                                           Unit                                 2025
                                                                                                                                                                        Participating in the industrial collaboration of Chinese materia medica in cold regions to promote the
                       Total R&D investment                                 Ten Thousand Yuan                          20,351.82
                                                                                                                                                             Case       development of regional industrial chains
     R&D Expenditure as a Percentage of Operating Revenue                             %                                  1.27                            In March 2025, Shiyitang Chinese Medicine, as one of the
                                                                                                                                                         chain-leader enterprises in Heilongjiang province's Chinese
          R&D Expenditure as a Percentage of Operating                                %                                  3.54
                 Revenue of Industrial Sector                                                                                                            materia medica industry chain, co-organized the "Cold-Region
                   Proportion of R&D personnel                                        %                                  10.54                           Longjiang Medicines · Acanthopanax Senticosus" Industry Devel-
                                                                                                                                                         opment Conference. The conference focused on the resource
             Total Amount of Science and Technology
                    Innovation Awards Issued                                Ten Thousand Yuan                           215.33                           protection, standardized cultivation, industrial synergy, and value
         Number of Recognized Science and Technology                                                                                                     enhancement of authentic Chinese materia medica in cold regions
                     Innovation Projects                                            Items                                146
                                                                                                                                                         like Acanthopanax senticosus. It brought together representatives
                 Total number of valid patents held                                 Items                                220                             from relevant provincial government departments, scienti?c
                                                                                                                                                         research institutions, industry associations, and enterprises for
     Total number of invention patents applied for in the year                      Items                                 24                             exchanges and discussions to jointly explore collaborative devel-
                                                                                                                                                         opment paths for the Chinese materia medica industry chain. By
      Total number of invention patents granted in the year                         Items                                  1
                                                                                                                                                         building a multi-party communication platform, the Company                          The First IP Image of Hailong Chinese Herbal Medicine –
                                                                                                                                                                                                                                                             Shiyitang Vitality Xiaowu
               Total number of valid trademarks held                                Items                                774                             actively     promotes       the     integration     of    resources       and
                                                                                                                                                         upstream-downstream          collaboration     in   the   Chinese   materia
                                                                                                                                                         medica industry, fostering the construction and high-quality
                                                                                                                                                         development of a regional traditional Chinese medicine industrial
Ethics of Science and Technology                                                                                                                         cluster.
The Company's business management revolves around pharmaceutical R&D, technology development, and related scienti?c and
technological activities, with its business covering areas such as chemical drugs, traditional Chinese medicine, biological
products, and health products. In the management of its scienti?c and technological activities, the Company adheres to the princi-
ple of legal compliance, making ethics of science and technology requirements an important prerequisite for R&D management
and scienti?c research cooperation to ensure that related activities are carried out in an orderly manner within a standardized
framework.
The Company complies with national requirements related to technology ethics and research management, such as Good Clinical
Practice, the Measures for the Ethical Review of Life Sciences and Medical Research Involving Human Participants, and the
Measures for the Review of Ethics of Science and Technology (Trial). Through internal systems like the R&D Project Management
Measures, it standardizes the initiation, implementation, and collaborative research of R&D projects. The systems stipulate that if
an R&D project involves clinical trials, non-clinical studies, or entrusts third parties to conduct related research activities, it must
be executed in strict accordance with current national laws, regulations, and regulatory requirements. Compliance responsibilities
must also be clearly de?ned in cooperation or entrustment agreements to ensure that the entire research process meets ethical
and compliance requirements.
                                                                                                                                                                                “Cold-Region Longjiang Medicines · Acanthopanax Senticosus” Industry Development Conference
The Company itself does not conduct research activities involving human clinical trials or animal experiments. In cases of commis-
sioned research or external cooperation, the Company requires its partners to possess the corresponding quali?cations by law and
imposes management constraints on their research conduct to ensure compliance with national ethics of science and technology
and regulatory requirements, thereby preventing potential ethical and compliance risks at the source. During the reporting period,
the Company had no instances of violating laws and regulations related to the ethics of science and technology.
                                             Message           About              2025 Key                                                     Governance and Compliance                                     Green Operations to     Employee Development
                       About This                                                                       Sustainability                                                          Product System for Value
                                             from the         Hapharm           Performance in                                 Special Topic   to Solidify a Foundation for                                  Advance Low-Carbon       to Build a Safe and   Appendix             2025 Sustainability Report
                        Report                                                                          Management                                                                      Creation
                                             Chairman          Group             Sustainability                                                       Stable Growth                                             Management               Shared Future
Product Quality and Safety Management
                                                                                                                                                Opportunity name                     Speci?c description                  Time horizon          Financial impact        Response measures
                                                                                                                                                                                                                                                                       Continuously optimize
                                                                                                                                                                              Product quality consistency and
                                                                                                                                                                                                                                                Revenue growth,        the quality management
Governance
                                                                                                                                                                              stability are continuously
                                                                                                                                                Quality improvement                                                        Medium and           enhanced brand         system, and strengthen
                                                                                                                                                                              improved, and quality management
                                                                                                                                                opportunity                                                                long term            premium, and           quality control and
                                                                                                                                                                              capabilities are steadily strength-
                                                                                                                                                                                                                                                improved cash ?ow      quality review through-
The Company always places product quality and drug safety at the core of its business management. Adhering to the principle of                                                ened
                                                                                                                                                                                                                                                                       out the entire process
"compliance ?rst, full-process control, and continuous improvement," it strictly follows the requirements of laws and regulations
such as the Drug Administration Law of the People's Republic of China, Good Manufacturing Practice (GMP), and Good Supply
Practice for Drugs (GSP). The Company has established an integrated quality management system that covers the entire industri-
al chain and complies with industry regulatory standards. It has formulated and implemented policy documents such as the
Management System of the Comprehensive Quality Management Committee and the Quality Document Management Procedures
of the Joint-Stock Company to clarify quality management responsibilities, processes, and supervision mechanisms, building a                   Full-Lifecycle Quality Management
quality management system that meets the regulatory requirements of the pharmaceutical sector.
                                                                                                                                               The Company systematically incorporates product quality and drug safety into its business management and quality governance
The Company continuously improves its quality management system structure. The Quality and Manufacturing Technology
                                                                                                                                               systems, gradually forming a management model guided by full-lifecycle quality management. The Company integrates quality
Department leads the overall coordination of quality management system development, operational supervision, and continuous
                                                                                                                                               management requirements into every stage of the product life cycle, from R&D to post-market surveillance. By combining system
improvement efforts. Each production, operation, and R&D entity, in line with its own business characteristics, strictly implements
                                                                                                                                               development with process control, it promotes the transformation of quality management from a singular focus on production
mandatory standards such as GMP and GSP. They formulate quality management system documents that match their product
                                                                                                                                               control to a comprehensive, front-end management approach, providing continuous assurance for product quality stability and
types and business scopes, ensuring seamless integration of quality management in organizational structure, system execution,
                                                                                                                                               drug safety.
                                                                                                                                               ?                                                    ?                                                  ?
and daily operations, thereby comprehensively strengthening the foundation of quality control.
                                                                                                                                                          Product R&D stage                                Production and distribution stage                   Product post-market stage
Strategy
                                                                                                                                                   Adhering to the philosophy of                           The Company continuously                         The Company has established
The Company focuses its core efforts on building a compliant and ef?cient quality management system, pursuing the "dual zero"                      "Quality by Design," the                                improves its quality manage-                     a mechanism for monitoring
goal, and achieving quality excellence. It systematically enhances its quality management capabilities by focusing on areas such                   Company systematically                                  ment mechanism, covering raw                     adverse drug reactions and
as quality operation evaluation, quality risk prevention and control, digital and intelligent application in quality, and the develop-             conducts quality risk assess-                           and auxiliary material access,                   quality feedback, collecting
ment of professional talent echelons. Risks and opportunities related to product quality and safety are integrated into the daily                  ments, process validations,                             supplier audits, production                      safety information through
operation and evaluation of the quality management system.                                                                                         and stability studies during                            process control, ?nished                         multiple channels and
                                                                                                                                                   drug formulation design,                                product inspection and release,                  conducting analysis, evalua-
      Risk name                     Speci?c description          Time horizon        Financial impact           Response measures                  process development, and                                warehousing and transporta-                      tion, and reporting in accor-
                                                                                                                                                   technology transfer. It de?nes                          tion, and product traceability. It               dance with regulatory
                                                                                                            Strengthen standardized
                                                                                                                                                   product quality standards,                              strengthens quality control of                   requirements. Concurrently,
                                                                                                            control throughout the entire
                                                                                                                                                   critical quality attributes, and                        raw and auxiliary materials by                   the Company has formulated
                                                                                                            life cycle and process,
                                                                                                            enhance the precision of
                                                                                                                                                   critical process parameters to                          implementing tiered audits and                   and implemented product
                                                                                                            process control, reinforce             ensure that R&D outcomes                                dynamic management of                            recall management
                           Quality control measures in R&D,                                                 quality awareness and                  have stable and reproducible                            suppliers. During the produc-                    documents, which specify
                                                                                   Product recall losses,
                           production, or testing are                                                       professional capability                production conditions before                            tion process, it reinforces                      recall classi?cation standards,
     Risk of quality                                             Medium and        compensation
                           inadequately implemented, and the                                                cultivation, promote a                 entering the industrialization                          standardized requirements for                    disposal procedures, and
     control failure                                             long term         expenses, and
                           quality management system has                                                    proactive risk prevention and          stage. Relevant R&D data and                            key processes, critical                          responsibilities. When
                                                                                   reduced revenue
                           operational weaknesses                                                           control mechanism, and                 change information are                                  equipment, and operating                         potential quality or safety risks
                                                                                                            establish a diversi?ed quality         managed and controlled in a                             personnel to ensure that                         are identi?ed, the Company
                                                                                                            audit and supervision system
                                                                                                                                                   standardized and traceable                              production activities remain                     can promptly initiate recall
                                                                                                            to comprehensively build a
                                                                                                                                                   manner, reducing the                                    controlled. In the inspection                    measures of the appropriate
                                                                                                            line of defense for quality
                                                                                                                                                   likelihood of quality ?uctua-                           and release stage, an indepen-                   level, leveraging its product
                                                                                                            and safety
                                                                                                                                                   tions in subsequent produc-                             dent quality management                          traceability system to ensure
                                                                                                                                                   tion and distribution stages                            function implements a                            that risks are controllable and
                                                                                                             Continuously track
                           Drug regulatory policies and                                                                                            from the source.                                        multi-level review and release                   disposal is effective.
                                                                                   Rising compliance         regulatory changes, improve
                           technical standards are continu-
  Regulatory compli-                                             Medium and        costs and heightened      the quality management                                                                        process, and no product is
                           ously updated, posing a risk of
  ance risk                                                      long term         risk of asset             system, conduct compli-                                                                       allowed to enter the market
                           delayed alignment in the quality
                                                                                   impairment                ance training, and perform                                                                    without approval.
                           management system
                                                                                                             regular system assessments
                                        Message             About            2025 Key                                                      Governance and Compliance                                      Green Operations to   Employee Development
                     About This                                                                     Sustainability                                                          Product System for Value
                                        from the           Hapharm         Performance in                                  Special Topic   to Solidify a Foundation for                                   Advance Low-Carbon     to Build a Safe and      Appendix              2025 Sustainability Report
                      Report                                                                        Management                                                                      Creation
                                        Chairman            Group           Sustainability                                                        Stable Growth                                              Management             Shared Future
Based on the actual needs of product quality management, the Company formulates an annual quality improvement plan, de?ning
key improvement directions and implementation milestones, and organizes its af?liated enterprises to advance quality improve-
                                                                                                                                                       Case       Honing elite skills through practice and demonstrating true expertise in competition
ment work as planned. Through regular internal quality audits, management reviews, and evaluations of improvement effective-
ness, combined with dynamic monitoring and systematic optimization of the entire process, the Company continuously enhances
the maturity of its quality management. This drives a steady improvement in product quality and drug safety levels, effectively
safeguarding public safety and ef?cacy in medication use.                                                                                          In November 2025, the Company organized a "Qual-
                                                                                                                                                   ity Inspector Competition". The competition adopt-
                                                                                                                                                   ed a format combining "theoretical assessment and
Quality Management System Capabilities Building                                                                                                    on-site practical operation" to comprehensively
                                                                                                                                                   evaluate the inspectors' understanding of regula-
                                                                                                                                                   tions,    professional      judgment,     and       operational
The effective operation of the quality management system relies on the combined efforts of system execution, personnel capabili-                   standards. The theoretical assessment focused on
ties, and organizational synergy. The Company continuously improves its quality management systems and business processes,                         quality     standards,      inspection     principles,     and
systematically integrating quality management requirements into R&D, production, sales, service, and related business segments.                    problem analysis skills, while the on-site practical
This promotes stable and effective linkage and operation of quality management across all stages.                                                  operation emphasized the execution of standard
                                                                                                                                                   operating procedures and actual inspection skills.
To reinforce the implementation of quality responsibilities, the Company uses positive incentive mechanisms to guide employees                     Through this competition, which promoted learning
to proactively ful?ll their quality duties. For key positions such as quality management, production operations, and inspection and                and practice, a platform for technical exchange in
testing, it implements professional skill competitions, job incentives, and rewards for quality improvement suggestions. It also                   quality inspection was established. It effectively
links quality performance with individual evaluations and performance results, ensuring that employees continuously improve                        enhanced the professional capabilities and regula-
their operational standardization and work quality in their daily work.                                                                            tory awareness of the inspection personnel, provid-                                 Quality Inspection Staff Skill Contest
                                                                                                                                                   ing talent support for the stable operation of the
At the same time, the Company regards professional capability building as a crucial guarantee for the long-term effective opera-                   quality management system.
tion of its quality management system. Through a combination of systematic training and practical experience, it continuously
enhances the understanding and execution capabilities of quality management, production, and inspection personnel regarding
regulatory requirements, technical standards, and quality risks. This approach promotes the transformation of quality manage-
ment from a system requirement to a level of excellence, solidifying the foundation for the sustained and effective operation of
product quality and safety management.
                                                                                                                                                       Case       Heilongjiang Provincial Drug Quality Inspector Employee Professional Skills Competition
          Case      Enhancing professional capabilities in the quality technology sequence
                                                                                                                                                   In December 2025, the Company selected 13 contestants
       The Company continues to advance the professional capability                                                                                to participate in the Heilongjiang Province Drug Quality
       building of its quality technology sequence. It has organized eight                                                                         Inspector Professional Skills Competition, with nine of
       subsidiaries and af?liates to complete the compilation of the Enter-                                                                        them achieving outstanding results, including sweeping
       prise-Level Quality Technology Professional Capability Manual and                                                                           the ?rst and second prizes. During the preparation
       its supporting question bank. In accordance with the latest manage-                                                                         period, the Company determined the ?nal contestants
       ment requirements of the 2025 edition of the Pharmacopoeia of the                                                                           through multiple rounds of competitive assessments and
       People's Republic of China, the Company has systematically                                                                                  invited professional instructors to conduct specialized
       optimized the Quality Inspection Professional Capability Enhance-                                                                           practical training to help them master key assessment
       ment Manual of the Company. On this basis, the Company simultane-                                                                           points and enhance their competitiveness. The competi-
       ously conducted specialized training and assessments for quality                                                                            tion consisted of two parts: theory and practical opera-
       technology inspection personnel, covering eight enterprises to                                                                              tion, comprehensively testing the contestants' profes-
       solidify the professional capabilities of the quality management                                                                            sional knowledge and practical skills. Leveraging their
       system. To promote and implement the new edition of the Pharmaco-                                                                           solid     foundation     and   craftsmanship,        the   Hapharm
       poeia of the People's Republic of China, a total of 104 internal and                                                                        contestants won multiple honors in the ?erce competi-
                                                                                             Quality technology training
       external training sessions were organized during the reporting                                                                              tion, inspiring all quality inspection personnel in the
       period, covering 1,838 participants. This has continuously enhanced                                                                         Company to re?ne their skills and jointly build a line of
       the understanding and execution level of inspection personnel                                                                               defense for drug quality and safety.
       regarding the new standards, ensuring that inspection work                                                                                                                                                                           Provincial Drug Quality Inspector
                                                                                                                                                                                                                                             Professional Skills Competition
       complies with the latest regulatory requirements.
                                             Message                About                  2025 Key                                                        Governance and Compliance                                 Green Operations to   Employee Development
                       About This                                                                               Sustainability                                                            Product System for Value
                                             from the              Hapharm               Performance in                                    Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix             2025 Sustainability Report
                        Report                                                                                  Management                                                                        Creation
                                             Chairman               Group                 Sustainability                                                          Stable Growth                                         Management             Shared Future
Impact, Risks, and Opportunities                                                                                                                           Indicators and Objectives
 In response to the high requirements of the pharmaceutical sector for product safety, compliance, and risk controllability, the                           Focusing on its established quality objectives, the Company continuously monitors and evaluates key quality indicators. By
 Company has integrated product quality-related impacts, risks, and opportunities into a uni?ed quality management framework.                              improving risk prevention and control measures and operational management mechanisms, it promotes the continuous improve-
 This framework covers key stages such as R&D, production, supply chain, distribution, and post-market management, forming a                               ment and effective operation of its quality management system, ensuring the implementation of quality objectives and phased
 risk management process that spans the entire product lifecycle. By embedding quality risk management requirements into its                               management requirements.
 daily quality operations, the Company continuously identi?es factors that may affect product quality, drug safety, operational
 stability, and market trust, thereby promoting a continuous shift in quality management towards proactive identi?cation and
 in-process control.                                                                                                                                                  During the reporting period, the Company
 The Company systematically identi?es quality-related risks and potential impacts through channels such as the execution of                                        No major quality accidents throughout the year                                     non-conformance announcements
 quality management systems, production process control, supplier quality management, pharmacovigilance information monitor-
 ing, and internal and external audits. It conducts graded assessments based on the likelihood and severity of the risks. For major                                                       ?   time                                                                  ?   item
 or urgent quality risk events, the Drug Safety Committee coordinates the assessment, the Quality Management Department takes
                                                                                                                                                                         pass rate in supervisory inspections                                              product release pass rate
                                                                                                                                                                                          ???                                                                     ???
 the lead, and relevant business departments participate collaboratively to ensure that risk information is identi?ed, effectively
 judged, and responded to in a timely manner. During the reporting period, the quality audit coverage rate for pharmaceutical                                                                        %                                                                         %
 manufacturing enterprises, R&D enterprises, and non-pharmaceutical business-related enterprises was 100%.
                                                                                                                                                            Pharmacovigilance
                                                                      Regulatory spot               Adverse reaction              Drug safety
  Internal quality monitoring          Customer complaints
                                                                         checks                       monitoring                  information              The Company conscientiously ful?lls its primary responsibility as a Marketing Authorization Holder, treating pharmacovigilance as
                                                                                                                                                           a crucial lever for ensuring public medication safety. It strictly adheres to regulations such as the Measures for the Reporting and
                                                                                                                                                           Monitoring of Adverse Drug Reactions and Good Pharmacovigilance Practice. It has established a pharmacovigilance center
                                                                                                                                                           staffed with full-time professionals to uniformly coordinate and supervise pharmacovigilance activities. A pharmacovigilance
                                                                                                                                                           management platform has been developed to unify systems, standards, operational procedures, and assessment requirements. It
  Production     process                                                                                                         Product       adverse
                                                                                                                                                           also conducts regular supervision, inspection, and guidance for its subsidiary enterprises and drug research institutions to ensure
  supervision, product              After-sales calls,             Spot     checks      by         Adverse drug reaction         reaction/drug
                                                                                                                                                           that all pharmacovigilance activities are conducted in compliance with regulations.
  and material inspec-              of?cial website,               drug       regulatory           monitoring   system,          safety    information
  tion, deviation identi-           store feedback                 authorities                     customer complaints           obtained by compa-
                                                                                                                                                           The Company continuously collects drug safety information through multiple channels, including the National Adverse Drug
  ?cation                                                                                                                        ny employees
                                                                                                                                                           Reaction Monitoring System, customer complaints, feedback from medical institutions, and literature monitoring. Upon receiving
                                                                                                                                                           information about adverse reactions, it promptly records, assesses causality, and implements follow-up management. All informa-
                                                                                                                                                           tion meeting reporting criteria is classi?ed and submitted within speci?ed timeframes via the national direct reporting system for
                                                                                                                                                           adverse drug reactions in accordance with regulatory requirements. Based on regular analysis and assessment results, it dynami-
                                                                                                                                                           cally optimizes risk prevention and control measures to enhance the timeliness and effectiveness of its risk response.
                                                         Channels for identifying quality issues
                                                                                                                                                           At the same time, the Company continues to strengthen its professional capabilities in pharmacovigilance. Focusing on new
                                                                                                                                                           regulations and key inspection points, it organizes specialized pharmacovigilance training and incorporates course resources
                                                                                                                                                           from the National Center for ADR Monitoring, China and professional industry institutions, achieving full coverage of personnel in
In terms of risk response and control, the Company implements closed-loop management of quality abnormalities and potential
                                                                                                                                                           relevant positions. This continuously enhances professional judgment and compliance execution capabilities, providing strong
risks through mechanisms such as deviation management, change management, and corrective and preventive actions (CAPA).
                                                                                                                                                           support for the ongoing management of drug safety risks.
The Company analyzes the root causes and impact levels of risks and takes corresponding disposal measures based on the risk
level to prevent the escalation or recurrence of risks. By tracking the effectiveness of corrective actions, it continuously optimizes
its quality management systems and processes, steadily enhancing its overall quality management capabilities.
While strengthening quality risk prevention and control, the Company also focuses on the positive impacts and development
opportunities brought by enhancing its quality management capabilities. By continuously improving its quality management
system and enhancing product quality consistency and full-process compliance, the Company strengthens its adaptability to
changes in regulatory policies, solidi?es its foundation of market trust, and reduces the potential impact of quality issues on its
operations and ?nances from the source.
                                        Message              About                 2025 Key                                             Governance and Compliance                                   Green Operations to   Employee Development
                     About This                                                                    Sustainability                                                      Product System for Value
                                        from the            Hapharm              Performance in                         Special Topic   to Solidify a Foundation for                                Advance Low-Carbon     to Build a Safe and     Appendix                  2025 Sustainability Report
                      Report                                                                       Management                                                                  Creation
                                        Chairman             Group                Sustainability                                               Stable Growth                                           Management             Shared Future
Customer Rights and Interests and Service Assurance                                                                                                 Case       Professional service capability building for DTP pharmacies
                                                                                                                                                 In 2025, Renmintongtai continued to re?ne its DTP training system
                                                                                                                                                 in alignment with the professional service requirements of DTP
To ensure public medication safety and enhance service accessibility, the Company has established and implemented internal                       pharmacies. It organized targeted training sessions led by physi-
policies such as the Customer Service Management System. It embeds customer service requirements into product information                        cians from Grade A tertiary hospitals and senior licensed pharma-
management, service response, and daily operations to promote standardized and orderly customer service activities, effectively                  cists, employing a blended approach combining online and of?ine
safeguarding the legitimate rights and interests of customers and consumers. Aligned with its corporate culture and values, it                   learning with self-study. The training covered multiple key disease
uni?es customer service standards and codes of conduct, clarifying a service orientation centered on integrity, professionalism,                 areas and core business modules, strengthening pharmacists'
collaboration, and ef?ciency. It continuously cultivates a professional, standardized, pragmatic, and ef?cient service image to                  professional      capabilities   in   full-cycle    patient   management,
enhance brand reputation and customer satisfaction.                                                                                              cold-chain drug handling standards, and compliant service delivery.
Concurrently, the Company regards professional capability development as a critical enabler. Focusing on key service scenarios                   Building on this foundation, Renmintongtai innovatively introduced
such as rational drug use guidance, chronic disease management support, and special medication assurance, it continuously                        an AI-powered intelligent learning and practice platform, with drug
enhances the professional competence and service capabilities of front-line staff, driving the evolution of customer service from                consultation and patient follow-up as core training scenarios.
basic support toward more professional, re?ned, and sustained assistance.                                                                        Through routine knowledge exercises and simulated follow-up
                                                                                                                                                 drills, the platform helps pharmacists consolidate professional
                                                                                                                                                 knowledge on drug indications, dosage, and administration,
                                                                                                                                                 standardize service procedures and communication approaches,
          Case     Special topic training on chronic disease management to enhance frontline pharmacy service capabilities                       and enhance the professionalism and consistency of patient
                                                                                                                                                 follow-ups.
        Renmintongtai periodically organizes training on key disease management, focusing on the long-term medication
        and health management needs of patients with chronic diseases. These sessions concentrate on high-prevalence
        chronic conditions such as diabetes, systematically explaining disease characteristics, key points of standardized                                                                                                                 AI-Powered Intelligent Learning
                                                                                                                                                                                                                                                and Practice Platform
        medication use, and related health management content to enhance the professional service capabilities of
        front-line employees.
        In October 2025, Renmintongtai invited a chronic disease management expert to deliver a special training session
        on Chronic Disease Management for Diabetes, covering disease mechanisms, complication risks, individualized
        medication, and lifestyle interventions. Sixty front-line store employees participated, effectively enhancing their
        practical competencies in chronic disease identi?cation, medication guidance, and patient communication.
                                                                                                                                        The Company has established the Quality Complaint Manage-
                                                                                                                                                                                                                                 During the reporting period, the Company
                                                                                                                                        ment System. When customer complaints or quality-related
                                                                                                                                        issues arise, it follows established procedures for acceptance,
                                                                                                                                        investigation, resolution, feedback, and corrective action. A
                                                                                                                                        tiered management approach is applied based on the nature and
                                                                                                                                        severity of the issue, with clear assignment of responsible parties
                                                                                                                                                                                                                                 Handled   ???         % customer feedbacks
                                                                                                                                        and handling requirements. Relevant personnel promptly identify
                                                                                                                                        root causes, implement corrective measures, and track their
                                                                                                                                        effectiveness, promoting closed-loop issue management and
                                                                                                                                        continuous improvement of service quality to prevent recurrence
                                                                                                                                        of similar issues.
                                                                                                                                        Considering store layouts and actual service scenarios, the Company is gradually exploring the appropriate extension of conve-
                                                                                                                                        nient services without compromising the standardized operation of its core business. Selected stores provide essential conve-
                                                                                                                                        nience support and basic assistance to residents of surrounding communities and outdoor workers, enhancing service accessibil-
                                                                                                                                        ity and enabling stores to function not only as healthcare access points but also as community service hubs. By organically
                                                                                                                                        integrating customer service with quality management, terminal operations, and community engagement, the Company continu-
                                                                                                                                        ously shifts its customer relationships from transactional interactions toward more stable and sustainable service partnerships,
                                           Training on chronic disease management for diabetes
                                                                                                                                        systematically addressing the diverse needs of different groups.
                                        Message              About                2025 Key                                              Governance and Compliance                                   Green Operations to   Employee Development
                     About This                                                                    Sustainability                                                      Product System for Value
                                        from the            Hapharm             Performance in                          Special Topic   to Solidify a Foundation for                                Advance Low-Carbon     to Build a Safe and   Appendix           2025 Sustainability Report
                      Report                                                                       Management                                                                  Creation
                                        Chairman             Group               Sustainability                                                Stable Growth                                           Management             Shared Future
                                                                                                                                        In advertising and communications management, the Company implements a uni?ed content review system and a tiered account-
                                                                                                                                        ability framework. All advertising and promotional materials must undergo internal review and ?ling. Promotions involving pharma-
          Case     Consumer training and interactive service programs
                                                                                                                                        ceuticals or health-related content are subject to statutory review requirements and pre-publication compliance and risk assess-
                                                                                                                                        ments. In media collaborations and new media communications, it adheres to standardized expression and cautious publishing
       The Company continuously implements consumer training and interactive service programs. Through standardized
                                                                                                                                        practices to prevent inappropriate promotion and compliance risks. At the point of service, the Company relies on its retail stores
       health education and service activities, it enhances public health literacy and terminal service quality, extending
                                                                                                                                        to uniformly implement standardized service processes and pharmaceutical care requirements, guiding consumers toward rational
       customer engagement beyond transactional interactions toward long-term service relationships.
                                                                                                                                        and safe medication use through structured medication counseling and service management, thereby avoiding misleading recom-
                                                                                                                                        mendations or improper marketing practices.
       The program primarily leverages chain pharmacies as its main platform, complemented by community and public
       cultural venues, to establish a multi-scenario service model. Through patient education, health lectures, and interac-
                                                                                                                                        Additionally, the Company emphasizes the social value of health communication, disseminating content on drug safety, rational
       tive experiences, it delivers scienti?c and standardized knowledge on medication use and health management to
                                                                                                                                        drug use, and health science through of?cial channels to enhance public health awareness. To meet advertising compliance and
       consumers. The Company collaborates with chain partners on activity planning and execution to enhance store
                                                                                                                                        service standardization requirements, it regularly organizes training on relevant regulations and practical implementation, cover-
       service capabilities and accessibility. In 2025, the program conducted a total of 405 sessions, reaching approximate-
                                                                                                                                        ing key areas such as advertising production and review procedures, of?cial website and new media content operations, and
       ly 13,000 consumers. While improving service engagement and consumer satisfaction, it also accumulated practical
                                                                                                                                        promotional standards for live-streaming and e-commerce platforms. This further strengthens compliance awareness and risk
       experience for re?ning the terminal service system and advancing health science communication.
                                                                                                                                        mitigation capabilities among relevant personnel, promoting more standardized and orderly external communications and terminal
                                                                                                                                        services.
                                                                                                                                                    Case       Advertising compliance review and regulatory training
                                                                                                                                                In May 2025, to further enhance the standardization and security of its external communications, the Company
                                                                                                                                                organized "Training on Advertising Compliance Review and Relevant Laws and Regulations," delivering systematic
                                                                                                                                                instruction to key personnel involved in external promotion through a blended online and of?ine format. The training
                                                                                                                                                addressed critical topics including advertising production and review procedures, of?cial website content operation
                                                                                                                                                standards, publishing requirements for of?cial WeChat accounts and self-media platforms, live-streaming content
                                                                                                                                                management, and promotional language standards for e-commerce platforms. It also provided focused guidance on
                                                    Consumer training and interaction                                                           advertising review essentials and common risks, contextualized within real-world work scenarios.
                                                                                                                                                                                                                               The training covered 105 personnel from
                                                                                                                                                                                                                               relevant departments, effectively enhancing
                                                                                                                                                                                                                               their understanding and execution of adver-
          Case     Emergency cold chain distribution to ensure the medication needs of medical institutions
                                                                                                                                                                                                                               tising compliance requirements, strengthen-
                                                                                                                                                                                                                               ing risk identi?cation and compliance aware-
       In April 2025, the Yichun Maternal and Child Health Hospital encountered an urgent medication need during clinical                                                                                                      ness in external communications, and provid-
       treatment that could not be met by its in-house inventory in the short term. Upon receiving the request, Logistics                                                                                                      ing assurance for the standardized and order-
       Center immediately activated its emergency customer service and distribution response mechanism, coordinating                                                                                                           ly conduct of the Company's marketing and
       logistics, warehousing, and quality functions to swiftly complete drug allocation, veri?cation, cold-chain packaging,                                                                                                   communication activities.
       and dispatch. During transportation, the Company strictly adhered to cold-chain transport and temperature control
       requirements, arranged dedicated direct delivery, and implemented end-to-end monitoring to ensure the drugs met
       usage standards for both delivery timeliness and quality safety. The required medications were delivered on time and
                                                                                                                                                                       Responsible marketing training
       safely, ensuring continuity of clinical treatment.
Responsible Marketing
                                                                                                                                                    During the reporting period, the Company
The Company places consumer health and legitimate rights at the core of its operations and upholds responsible marketing as a
fundamental principle of its market activities. It continuously standardizes its marketing and external communication practices. In
all marketing communication activities, it strictly complies with laws and regulations including the Advertising Law of the People's
Republic of China, the Drug Administration Law of the People's Republic of China, and the Law of the People's Republic of China                                                                         Performed   ??    responsible marketing audits
on the Protection of Consumer Rights and Interests. It has established a marketing compliance management mechanism covering
the entire process—from planning and review to publication—to ensure all content is truthful, accurate, and objective, without
exaggerating product ef?cacy, inducing health anxiety, or misleading consumers.
                                          Message               About               2025 Key                                                     Governance and Compliance                                 Green Operations to   Employee Development
                       About This                                                                         Sustainability                                                        Product System for Value
                                          from the             Hapharm            Performance in                                 Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix         2025 Sustainability Report
                        Report                                                                            Management                                                                    Creation
                                          Chairman              Group              Sustainability                                                       Stable Growth                                         Management             Shared Future
                                                                                                                                                 The Company continues to advance its transparent procurement system, leveraging a uni?ed SRM (supplier relationship manage-
Supply Chain Management                                                                                                                          ment) platform to enable end-to-end digital management of suppliers and ensure full traceability. Procurement activities strictly
and Security
                                                                                                                                                 adhere to the principles of openness, fairness, impartiality, full competition, and compliance & integrity, ensuring equal access to
                                                                                                                                                 procurement information for all quali?ed suppliers. The procurement process is fully traceable and auditable, effectively mitigating
                                                                                                                                                 risks of improper transactions and enhancing transparency and operational ef?ciency in procurement management.
                                                                                                                                                             Case       Digital platform empowering transparent procurement and industrial chain collaboration
In accordance with GMP and other applicable laws, regulations, and industry regulatory requirements, the Company has estab-
lished and continuously improved its supplier management system. Through policies including the Supplier Management Regula-                            To enhance standardization and transparency in procurement and sales and improve industrial chain collaboration
tions, Detailed Rules for Supplier Sourcing Management, and Management Procedures for Drug Supplier Evaluation Standards, it                           ef?ciency, the Company has advanced its supply chain management through digital transformation, establishing an
standardizes key processes—sourcing, onboarding, collaboration, evaluation, and exit—providing institutional assurance for the                         integrated upstream-downstream management system centered on its enterprise-level SRM (Supplier Relationship
security, compliance, and stable operation of the supply chain. The Board of Directors oversees supply chain strategy; senior                          Management) system and the SAP Hybris distributor platform. The dual-platform architecture enables seamless data
management coordinates strategic implementation; and the Tendering and Procurement Department is responsible for execution,                            integration across the entire procurement and sales chain, offering a uni?ed and open collaborative environment for
including supplier onboarding, evaluation, and risk control.                                                                                           upstream and downstream small and medium-sized enterprises (SMEs). As of the end of the reporting period, the
                                                                                                                                                       platforms served over 20,000 upstream suppliers and more than 4,000 downstream commercial customers, with SMEs
                                                                                                                                                       accounting for over 90%. Platform adoption has signi?cantly improved operational ef?ciency: order processing
                                                                          Information manage-                   Evaluation and                         ef?ciency increased by over 46%, procurement cycles shortened by approximately 30%, contract signing ef?ciency
             Sourcing                       Onboarding
                                                                                 ment                            classi?cation                         rose by 80%, and inventory data accuracy reached 99.8%. Through centralized procurement and compliance veri?ca-
     Search for potential           Potential suppliers register          Maintain uni?ed                 Conduct regular (at least                    tion mechanisms, the Company has reduced procurement costs, minimized inventory accumulation, and continuously
     suppliers through various      and submit quali?cation               supplier master data            annually) or ad hoc evalua-                  enhanced the standardization and security of supply chain operations.
     channels (e.g., internet,      documents on the SRM                  and database informa-           tions of quali?ed suppliers
     exhibitions, industry          platform. After passing               tion (potential,                across multiple dimensions—
     associations).                 review—which may include              quali?ed, blacklist) on         including quality, delivery,           The Company considers integrity and compliance as a fundamental prerequisite for supplier cooperation, strictly adhering to
                                    product testing and on-site           the SRM platform.               price, service, and overall            national laws and regulations and company policies. It maintains a "zero-tolerance" policy towards commercial bribery and
                                    inspections—they complete                                             capability—and apply                   improper trading practices. During the bidding and cooperation processes, the Company uniformly requires suppliers to sign the
                                    the onboarding process per                                            dynamic classi?cation                  HARBIN PHARMACEUTICAL GROUP CO., LTD. Bidder Integrity Commitment Letter. Performance under this commitment is
                                    the introduction plan and                                             (strategic, leverage, routine,         integrated into the supplier evaluation and management system, serving as a crucial basis for continued cooperation. Through
                                    become quali?ed suppliers.                                            bottleneck) and grading (A,            institutional constraints and process controls, integrity requirements are embedded into key aspects such as supplier onboarding,
                                                                                                          B, C, D) based on results.             bidding and procurement, and contract performance management, preventing integrity risks in the supply chain from the source
                                                                                                                                                 and ensuring the fairness and compliance of procurement activities.
                                                                          Relationship manage-              Performance manage-
                                      Exit and reinstatement
                                                                                  ment                             ment
                                    Suppliers failing evaluation         Establish communication          Engage with, support, and                        During the reporting period, the Company
                                    criteria or encountering             mechanisms, handle mutual        address suppliers experienc-
                                    major issues are removed             complaints, and provide          ing issues in quality, delivery,
                                    from the quali?ed supplier           support to suppliers with        or service (including issuing
                                    list or placed on the blacklist.     low ratings.                     warnings, suspending
                                    Reinstatement after exit                                              cooperation, downgrading, or                                    Achieved   ???%             signing rate for the Integrity Commitment Letter among bidding suppliers
                                    requires re-completion of the                                         blacklisting).
                                    onboarding process.
                                                        Supplier management process
                                                                                                                                                 Supply Chain Risk Management
           During the reporting period, the Company
                                                                                                                                                 The Company embeds risk management into the full-lifecycle management of its suppliers. By controlling access, monitoring
                Total number of suppliers            Proportion of local suppliers                  Local procurement ratio                      processes, and making dynamic adjustments, it systematically identi?es and addresses compliance and operational risks within
                                                                                                                                                 the supply chain. Prior to cooperation, it conducts audits focusing on key requirements such as compliant operations, quality and
                                                                                                                                                 safety, and business ethics to prevent high-risk entities from entering its supply system. During cooperation, it continuously
                      ?,???                                ??.?? %                                     ??.?? %                                   tracks supplier operational performance by integrating ful?llment records, issue feedback, and audit results, and takes timely
                                                                                                                                                 management actions in response to evolving risks to prevent their accumulation and spread.
                                       Message             About                    2025 Key                                                 Governance and Compliance                                 Green Operations to   Employee Development
                    About This                                                                           Sustainability                                                     Product System for Value
                                       from the           Hapharm                 Performance in                             Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix            2025 Sustainability Report
                     Report                                                                              Management                                                                 Creation
                                       Chairman            Group                   Sustainability                                                   Stable Growth                                         Management             Shared Future
Relying on internal audits and special inspections, the Company supervises and veri?es processes and key risk points related to
                                                                                                                                               Supply chain risk management goals
supplier management. Risks identi?ed through audits are incorporated into subsequent management and improvement cycles,
strengthening closed-loop risk prevention and control. By integrating information security and integrity requirements into audit
and process management, it ensures the standardization, transparency, and controllability of supply chain operations.                              Annual audit coverage for tier 1 suppliers ≥ 95%, ESG special audit coverage ≥ 50%
                                                                                                                                                   A supplier risk warning response time of ≤ 24 hours
         During the reporting period, the Company
     Conducted document audits for     Conducted on-site audits for         Had     ??        suppliers that underwent and passed
     ?,???          suppliers          ???        suppliers                 environmental and social audits
                                                                                                                                             Sustainable Supply Chain Management
                                                                                                                                             The Company continues to advance the development of a sustainable supply chain by leveraging policy documents such as the
                                                                                                                                             Supplier Management Regulations and the supplier full-lifecycle management mechanism. It incorporates sustainability require-
                                                                                                                                             ments—including environmental protection, product quality, work safety, labor practices, and business ethics—into supplier
                                                                                                                                             onboarding, cooperation, and evaluation processes. Through policy documents and procurement contract clauses, it clearly
                                                                                                                                             de?nes supplier responsibilities and obligations regarding compliant operations, anti-commercial bribery, and information protec-
                                                                                                                                             tion. Suppliers found to have committed serious legal violations, posed quality and safety hazards, or demonstrated commercial
          Case     Construction of GAP bases for core Chinese materia medica at Shiyitang Chinese Medicine
                                                                                                                                             dishonesty are subject to restrictions or termination of cooperation in accordance with applicable laws and regulations. During
                                                                                                                                             cooperation, the Company integrates factors such as quality and safety performance, ful?llment reliability, and compliance
        To strengthen source-level quality management of the traditional Chinese medicinal materials supply chain and
                                                                                                                                             records into supplier evaluation and tiered management, using evaluation outcomes to drive corrective actions and continuous
        ensure the stability, safety, and traceability of core Chinese materia medica raw materials, Shiyitang Chinese
                                                                                                                                             improvement, thereby promoting responsible supplier conduct and enhancing management capabilities to steer the supply chain
        Medicine focuses on building good agricultural practice (GAP) bases for Chinese materia medica, continuously
                                                                                                                                             toward greater standardization and sustainability.
        advancing standardized cultivation and quality control systems for authentic medicinal materials.
                                                                                                                                                                                                                                          During the reporting period, the Company
                                                                                                                                             The Company conducts supplier training centered on sustainable
        Shiyitang Chinese Medicine focuses on core varieties including Acanthopanax senticosus, Lonicera japonica,                           supply chain management requirements to reinforce understanding
        Forsythia suspensa, Scutellaria baicalensis, and Schisandra chinensis, collaborating with multiple Chinese materia
                                                                                                                                                                                                                                                         ???
                                                                                                                                             and implementation of quality, compliance, and responsibility
        medica cultivation enterprises to jointly build and share GAP bases, thereby advancing quality management require-                   standards, fostering supply chain collaboration and enhancing                                   Performed            supplier
        ments upstream to the cultivation stage. Relevant bases have successively passed the GAP compliance extension                        sustainability capabilities.                                                                           training sessions
        inspections conducted by the Heilongjiang Provincial Medical Products Administration. Among them, the cumulative
        inspected area for cultivation bases of Lonicera japonica, Acanthopanax senticosus, Forsythia suspensa, and Scute-
        llaria baicalensis exceeds 18,000 mu, achieving controllable sourcing, manageable processes, and traceable quality
        for major Chinese materia medica raw materials.
                                                                                                                                             Equal Treatment of Small and Medium-Sized Enterprises
                                                                                                                                             The Company upholds equal treatment of small and medium-sized enterprises (SMEs) in supplier management and procurement
                                                                                                                                             practices. Its bidding and procurement management system explicitly prohibits discriminatory or exclusionary conditions that
                                                                                                                                             restrict SME participation, ensuring they enjoy fair competition opportunities in accordance with the law.
                                                                                                                                             The Company publicly discloses procurement information via its of?cial website and third-party platforms, ensuring all suppliers—
                                                                                                                                             including SMEs—have equal access to procurement information, understand procedures, and can participate in competitive
                                                                                                                                             bidding. Additionally, the Company has established a standardized settlement and payment mechanism and strictly ful?lls
                                                                                                                                             contractual payment terms.and sustainable supply chain cooperation ecosystem.
                                                          GAP cultivation bases
                                        Message            About              2025 Key                                                  Governance and Compliance                                        Green Operations to      Employee Development
                     About This                                                                    Sustainability                                                           Product System for Value
                                        from the          Hapharm           Performance in                              Special Topic   to Solidify a Foundation for                                     Advance Low-Carbon        to Build a Safe and        Appendix                   2025 Sustainability Report
                      Report                                                                       Management                                                                       Creation
                                        Chairman           Group             Sustainability                                                    Stable Growth                                                Management                Shared Future
Information Security                                                                                                                                    During the reporting period, the Company
and Privacy Protection
                                                                                                                                                 Conducted attack-defense and emergency response drills
                                                                                                                                                                                   ?
                                                                                                                                                              Had con?rmed data security incidents
                                                                                                                                                                                   ?
The Company continuously enhances its information security and privacy protection governance system by establishing a
dedicated network and information security management organizational structure, including a Network and Information Security
Leading Group and an Emergency Response Working Group. These bodies coordinate decision-making on major information
security and privacy matters and provide uni?ed command and coordination for emergency responses to cybersecurity incidents,                            Had con?rmed customer privacy breach incidents
ensuring orderly and ef?cient risk response.
                                                                                                                                                                                  ?
At the policy level, the Company continuously re?nes its information security and privacy protection framework, centered on the                                                                                                                         Information security skills training
Regulations on the Management of Computer Use and Information Systems, which clearly de?ne norms for information system
usage, allocation of information security responsibilities, and requirements for data access and use—providing institutional assur-
ance for stable system operations and compliant data management. Concurrently, the Company strictly implements China's
Cybersecurity Classi?ed Protection requirements, organizing ?ling and assessment activities for its information systems. Its
of?cial website, collaborative of?ce system, and integrated business-?nance system have obtained Level II and Level III Classi?ed
Protection certi?cations, and the Company continuously elevates its overall security posture through third-party evaluations.           Medicine Accessibility Enhancement
In technical protection and operational management, the Company strengthens cybersecurity defenses and emergency response
                                                                                                                                        Governance
capabilities based on the actual operating conditions of its information systems. Through implementing cybersecurity initiatives,
conducting attack-defense drills, and performing phishing email simulations, it continuously assesses system resilience and
employee security awareness, promptly identifying and remediating potential vulnerabilities to enhance overall defensive and
incident response capabilities.                                                                                                         Medicine accessibility is a key topic in safeguarding public health and well-being and constitutes a core component and critical
                                                                                                                                        practice area of the Company's social responsibility. Its governance level and implementation effectiveness are directly linked to
The Company enforces strict privacy management for customer and patient information. Such information is collected only in              the fairness of medical resource allocation, the availability and affordability of pharmaceutical services, and ultimately the realiza-
legitimate and compliant business contexts and centrally managed through a uni?ed system platform, with clear requirements for          tion of societal health outcomes. To this end, the Company leverages a collaborative mechanism among multi-level governance
data storage, access control, and con?dentiality. Retention, dissemination, or disclosure of this information in non-work-related       bodies to continuously strengthen the governance foundation in medicine accessibility, systematically translating governance
contexts is prohibited. Upon personnel role changes or departures, the Company strictly enforces information handover and data          requirements into actionable measures. Through systematic governance, it empowers core objectives such as the decentralization
clearance protocols to ensure information security remains under control.                                                               of medical resources and enhanced accessibility of innovative medicines, thereby demonstrating its commitment to public health
                                                                                                                                        stewardship.
During the reporting period, Renmintongtai further revised the Management System and Standard Operating Procedures for
Specialty Pharmacies, adding speci?c patient privacy protection requirements. The revision mandates adherence to the principle
of data minimization in information collection and requires that patients be fully informed—at the time of initial service—about the    Strategy
purpose, scope, retention period, and protective measures related to data collection, with informed consent obtained accordingly.
It also re?nes standards for data desensitization and strengthens management requirements for information storage, use, and
                                                                                                                                                 Risk name                       Speci?c description                    Time horizon1           Financial impact             Response measures
transmission, thereby further safeguarding patient rights and enhancing service compliance and public trust.
Simultaneously, the Company continues to strengthen awareness and training on information security and privacy protection by
integrating management requirements into daily work?ows through thematic training sessions, internal platform communications,                                            The drug pricing mechanism is
and cautionary education. During the reporting period, it published 42 issues of cybersecurity awareness content and organized                                                                                                                                             Strengthen price
                                                                                                                                                                         in?uenced by multiple factors—
                                                                                                                                                                                                                                                                           management and market
security awareness and skills training programs focused on information system operations and business scenarios, continuously                                            including national centralized                                       Increased revenue
                                                                                                                                                Price                                                                    Short and                                         monitoring, and formulate
reinforcing the foundational management of information security and privacy protection.                                                                                  procurement policies, market                                         volatility and greater
                                                                                                                                                instability risk                                                         medium term                                       pricing strategies that
                                                                                                                                                                         competition dynamics, and                                            pro?t uncertainty
                                                                                                                                                                                                                                                                           align with cost changes
                                                                                                                                                                         ?uctuations in raw material costs—
                                                                                                                                                                                                                                                                           and market demand
                                                                                                                                                                         resulting in certain price volatility
                                                                                                                                            Impact duration refers to the time scope of material impacts on the Company. Short-term: within 1 year; medium-term: 1 to 5 years;
                                                                                                                                        long-term: more than 5 years.
                                                   Message                About                 2025 Key                                                           Governance and Compliance                                    Green Operations to   Employee Development
                             About This                                                                                  Sustainability                                                             Product System for Value
                                                   from the              Hapharm              Performance in                                       Special Topic   to Solidify a Foundation for                                 Advance Low-Carbon     to Build a Safe and     Appendix              2025 Sustainability Report
                              Report                                                                                     Management                                                                         Creation
                                                   Chairman               Group                Sustainability                                                             Stable Growth                                            Management             Shared Future
          Risk name                       Speci?c description                    Time horizon           Financial impact            Response measures
                                                                                                                                                                               Case       Focusing on full-course disease management to aid patient recovery
                                 The pharmaceutical supply chain                                                                                                           In November 2025, the Company hosted a lung cancer
                                 encompasses multiple segments—                                                                                                            patient education event titled "Foreseeing the Future,
                                                                                                                                  Optimize the supply chain
                                 production, warehousing, logistics,
                                                                                                       Decreased sales            and channel network, and                 Creating a New Life Together" at its DTP Management
       Poor channel              and last-mile distribution—with                 Short and
                                                                                                       revenue and higher         enhance supply assurance                 Center, attended by 22 patients. A chief physician from a
       distribution risk         uncertainties in channel coordina-              medium term
                                                                                                       operating costs            for key regions and critical             tumor hospital was invited as the keynote speaker to
                                 tion and delivery ef?ciency; supply
                                                                                                                                  products                                 share professional insights on key aspects of full-course
                                 assurance capacity in certain
                                 regions requires improvement                                                                                                              disease management, helping patients and their families
                                                                                                                                                                           develop a scienti?cally informed understanding of the
                                                                                                                                                                           condition. The event included one-on-one consultation
                                                                                                                                                                           sessions to facilitate discussions between patients and
                                                                                                                                                                           healthcare providers about treatment concerns. In collab-
                                                                                                                                                                           oration with physicians, the pharmacy established a
      Opportunity type                    Speci?c description                    Time horizon           Financial impact            Response measures                      fast-track consultation channel to streamline follow-up
                                                                                                                                                                           procedures and address access barriers. This event
                                                                                                                                                                           provided professional guidance and services, created a
                                                                                                                                                                                                                                                                 Exclusive patient education event
                                                                                                                                                                           platform for doctor-patient communication, and support-                                    for lung cancer patients
                                 Evolving public health needs and                                                                                                          ed standardized treatment and long-term health manage-
                                 growing demand for affordable,
                                                                                                                                 Advance product portfolios                ment for lung cancer patients.
                                 highly adaptable medicines in                                         Increased revenue
       Pharmaceutical                                                                                                            tailored for grassroots and
                                 grassroots and emerging markets                 Long-term             and higher cash
       innovation                                                                                                                emerging markets and
                                 continue to expand product                                            in?ows
                                                                                                                                 enhance market coverage
                                 application scenarios and market                                                                                                  In 2025, the Company further deepened its "Internet + Pharmaceutical Health" service model, with a core focus on enhancing
                                 opportunities                                                                                                                     medication purchasing convenience and upgrading health service experiences. It comprehensively optimized and scaled its O2O
                                                                                                                                                                   business system across chain stores. Leveraging the physical advantages of its of?ine store network and the technological
                                                                                                                                                                   enablement of its digital platforms, the Company successfully established an integrated "online + of?ine" service loop, ef?ciently
                                                                                                                                                                   meeting consumers' health and medication needs across all times and scenarios, signi?cantly expanding service reach and
                                                                                                                                                                   response ef?ciency.
Access Channels
                                                                                                                                                                                         Empowering science communication upgrades through expert livestreaming to improve public health
                                                                                                                                                                              Case       literacy
The Company has deep expertise in the pharmaceutical distribution sector and has built an ef?cient province-wide delivery
network leveraging high-quality channel resources, supported by strong market coverage and marketing capabilities. It has estab-
                                                                                                                                                                           In July 2025, the Marketing Company built a nutrition
lished a comprehensive terminal customer coverage system encompassing graded hospitals, primary healthcare institutions, and
                                                                                                                                                                           popular science platform via short videos. Aiming at
retail pharmacies. Long-standing cooperative relationships with key medical institutions and commercial clients are reinforced
                                                                                                                                                                           public    dietary      misunderstandings       and   nutritional
through continuous service quality improvements. In its retail segment, the Company focuses on re?ned operations and optimized
                                                                                                                                                                           needs, it converted professional nutritional knowledge
layout of directly operated stores, while utilizing DTP specialty pharmacies 1 and hospital-adjacent stores as key channels to
                                                                                                                                                                           into accessible and widely-spreadable content to lower
capture prescription out?ow, delivering professional and standardized pharmaceutical services to consumers.
                                                                                                                                                                           the public’s threshold for acquiring health knowledge.
                                                                                                                                                                           To guarantee content quality, a special team was estab-
As of the end of 2025, the Company operated 357 directly managed retail stores, including 226 stores in Harbin and 131 stores
                                                                                                                                                                           lished for content planning and production based on
outside the city. The Company had a total of 15 DTP specialty pharmacies to better meet patients’ medication needs. The DTP
                                                                                                                                                                           basic nutrition and real-life scenarios. Up to now, over
pharmacies cumulatively served 250,000 patients, with follow-up services covering nearly 190,000 visits.
                                                                                                                                                                           released, attracting more than 60,000 user interac-
                                                                                                                                                                           tions, which has effectively expanded popular science
                                                                                                                                                                           coverage and improved public health literacy.
    DTP pharmacies (Direct to Patient) refer to specialized pharmacies through which pharmaceutical manufacturers or distributors provide prescription
                                                                                                                                                                                                                                                               Employee Live Broadcast Column
drugs—primarily specialty and innovative medicines—directly to patients.
                                                    Message                 About                 2025 Key                                                              Governance and Compliance                                 Green Operations to   Employee Development
                             About This                                                                                     Sustainability                                                             Product System for Value
                                                    from the               Hapharm              Performance in                                          Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix          2025 Sustainability Report
                              Report                                                                                        Management                                                                         Creation
                                                    Chairman                Group                Sustainability                                                                Stable Growth                                         Management             Shared Future
Inclusive Healthcare                                                                                                                                                    Impact, Risk, and Opportunity Management
          Product pricing basis
                                                                                                                                                                        The Company systematically identi?es and manages impacts, risks, and opportunities related to medicine accessibility in pursuit
                                                                                                                                                                        of its goal to ensure public access to essential medicines. Considering evolving policy landscapes, market feedback, and opera-
          The Company adopts a market-oriented pricing mechanism, conducting nationwide competitive price surveys to                                                    tional performance, it continuously monitors factors—including drug price volatility, supply channel ef?ciency, and coverage in
          systematically understand market price baselines and regional patient affordability thresholds. Combined with                                                 grassroots and remote areas—that may affect medicine availability and affordability. Comprehensive assessments are conducted
          full-chain cost accounting of product manufacturing, it aligns pricing with market realities and ensures patient                                              across dimensions such as patient affordability, supply reliability, and service reach. For key identi?ed risks, the Company imple-
          affordability, ful?lling its corporate mission.                                                                                                               ments ongoing management through pricing justi?cation, channel network optimization, and service model enhancements,
                                                                                                                                                                        supported by dynamic tracking via operational data and market insights. While mitigating accessibility risks, it seizes opportuni-
                                                                                                                                                                        ties arising from innovative drug adoption, channel expansion into lower-tier markets, and service model innovation, driving more
                                                                                                                                                                        equitable and effective delivery of pharmaceutical resources to meet societal needs.
          Pricing data and changes for key products
                                                                                                                                                                        Indicators and Objectives
          Pricing of the key product, Nao An Pian from Hayao No.6 Factory, follows centralized procurement policy guidance.
          In 2023, it was successfully awarded a contract in the National Traditional Chinese Medicine Procurement Alliance's
          volume-based procurement program, with winning bid prices of RMB 22.41 per box (24-tablet pack) and RMB 33.12
          per box (36-tablet pack)—a 17% reduction that effectively alleviates patient medication costs. This price has been                                                    Target
          progressively implemented across provinces since September 2023. Following the completion of a new bidding
          round in 2025, the same price remains in effect nationwide, strongly supporting inclusive pricing objectives.
                                                                                                                                                                                                Launched products are timely registered on provincial procurement platforms nationwide to achieve
          Fair pricing strategy
                                                                                                                                                                                                rapid terminal sales coverage at all levels of medical and health institutions across the country.
          A comprehensive pricing justi?cation mechanism has been established, covering analysis of market competition
          dynamics, competitive price benchmarking, invoicing price calculation, and compliance validation. Through multi-di-
          mensional systematic review, pricing strictly adheres to national pharmaceutical pricing policies while maximizing
          patient bene?ts, effectively reducing ?nancial burdens and re?ecting a commitment to inclusive health access.
                                                                                                                                                                                                The Company actively participates in national volume-based procurement and relevant policies includ-
                                                                                                                                                                                                ing the "Three Entries" initiative. It effectively improves public access to medicines and reduces
                                                                                                                                                                                                residents’ economic burden of medical treatment and medication.
                Case       Responding to the hierarchical diagnosis and treatment policy to help enhance medication accessibility
            Promoting hierarchical medical care and improving access to medicines at grass-
            roots level has been a top priority of China’s medical and health work in recent
            years. The state has continuously introduced relevant policies, including incorpo-
            rating village clinics into medical insurance pooling, advancing the "Three Entries"
            of centralized procurement, improving compact county medical communities, and
            realizing grassroots medication linkage.
            The Company deeply participates in national volume-based procurement and the
            National Chinese Patent Medicine Alliance Procurement. Its products have been
            selected in multiple batches of such procurement projects. The substantially
            reduced selected prices effectively meet the medication demands of medical
            institutions and ease patients’ medication burden.
            Regarding the "Three Entries" policy, the Company actively applies for relevant
            product listings. Nao’an Tablets, Fosfomycin Sodium for Injection, Ceftriaxone
            Sodium for Injection, Cefazolin Sodium for Injection and Cefradine Capsules have
            been included in the provincial "Three Entries 1" catalogues of multiple regions.
    Refers to the access of centralized-procurement medicines to grassroots medical institutions, private medical institutions and retail pharmacies.
 Green Operations to
Advance Low-Carbon
       Management
     The content of this chapter
     Environmental Compliance Management       ??
     Climate Change Tackling                   ??
     Energy and Resource Management            ??
     Pollutant Emissions                       ??
     Waste Management                          ??
     Ecosystem and Biodiversity Conservation   ??
                                         Message            About               2025 Key                                               Governance and Compliance                                         Green Operations to      Employee Development
                     About This                                                                     Sustainability                                                         Product System for Value
                                         from the          Hapharm            Performance in                           Special Topic   to Solidify a Foundation for                                      Advance Low-Carbon        to Build a Safe and       Appendix                 2025 Sustainability Report
                      Report                                                                        Management                                                                     Creation
                                         Chairman           Group              Sustainability                                                 Stable Growth                                                 Management                Shared Future
Environmental Compliance Management                                                                                                                   Case            The Company’s organization of specialized environmental protection training to strengthen the
                                                                                                                                                                      green compliance line of defenses
                                                                                                                                                   In September 2025, the Company led a specialized
                                                                                                                                                   environmental       protection      training    session     involving
The Company strictly complies with relevant laws and regulations, including the Environmental Protection Law of the People's
                                                                                                                                                   relevant personnel from its subsidiaries, with a total of 30
Republic of China, the Law of the People's Republic of China on the Prevention and Control of Environmental Pollution by Solid
                                                                                                                                                   participants. This training was closely aligned with the
Waste, the Air Pollution Prevention and Control Law of the People's Republic of China, and the Water Pollution Prevention and
                                                                                                                                                   current severe environmental regulatory situation and
Control Law of the People's Republic of China. It has formulated and implemented the Hapharm Group Environmental Protection
                                                                                                                                                   precisely met the Company's actual needs for environmen-
Management Measures. The Company continuously advances pollution prevention and control efforts to ensure stable and
                                                                                                                                                   tal management. The content covered core modules such
compliant emissions of all pollutants. With a core focus on ful?lling its primary environmental responsibilities and strengthening
                                                                                                                                                   as in-depth interpretation of environmental laws and
end-to-end supervision, it steadily progresses in building a green manufacturing system. Its subsidiary, Sanjing Mingshui, was
                                                                                                                                                   regulations, analysis of typical environmental violation
awarded the National Green Factory designation in 2024.
                                                                                                                                                   cases, practical methods for corporate environmental
                                                                                                                                                   self-inspection,     and     emergency       response      plans    for
The Company has established a tiered environmental management responsibility system, designating the principal executives of
                                                                                                                                                   environmental incidents. The training effectively strength-
each subordinate production enterprise as the primary persons accountable for environmental protection. It centrally coordinates                                                                                                     The Company's environmental protection training
                                                                                                                                                   ened the environmental compliance awareness and sense
annual internal audits of the environmental management system and maintains end-to-end oversight to ensure responsible
                                                                                                                                                   of responsibility of the participants from all subsidiaries,
entities complete closed-loop corrective actions for any weaknesses or risks identi?ed, guaranteeing the system's sustained and
                                                                                                                                                   systematically enhancing their capabilities in environmen-
high-quality operation.
                                                                                                                                                   tal risk identi?cation, hazard investigation, and emergency
                                                                                                                                                   response, laying a solid foundation for the Company to
The Company has formulated and issued the Emergency Response Plan for Environmental Emergencies, aiming to effectively
                                                                                                                                                   continuously strengthen its environmental management
respond to environmental emergencies triggered by various production safety accidents and natural disasters. This plan is
                                                                                                                                                   line of defense and achieve green and compliant opera-
designed to prevent the diffusion of pollutants and toxic and hazardous substances into the atmosphere, water bodies, soil, and
                                                                                                                                                   tions.
other environmental media outside the plant boundaries, thereby minimizing the negative impact on the environment. At the same
time, the Company organizes environmental protection training, conducts emergency drills, and establishes an effectiveness
evaluation mechanism to ensure the operability and effectiveness of the plan. Additionally, the Company continuously improves
its long-term environmental management mechanisms, regularly carries out environmental hazard investigation and recti?cation
                                                                                                                                       Climate Change Tackling
work, ensures effective investment in hazard recti?cation funds, and prevents the occurrence of environmental risk incidents.
          During the reporting period, the Company
                                                                                                                                       Governance
       Conducted   ??     emergency drills for environmental risk incidents
                                                                                                                                       The Company deeply implements the national "dual carbon" strategic deployment, incorporating climate change tackling into its
                                                                                                                                       core corporate governance and steadily promoting energy conservation and carbon reduction efforts based on its existing
       Organized   ?,???          participants for emergency drills of environmental risk incidents
                                                                                                                                       management structure. In terms of carbon emission governance, the Company has established standardized working mechanisms
                                                                                                                                       for Scope 1 and Scope 2 carbon emission inventories. It conducts comprehensive inventories and precise accounting according
       Conducted   ??      environmental management training sessions
                                                                                                                                       to a set cycle, while simultaneously sorting, archiving, and verifying carbon emission data to ensure its authenticity and traceabili-
                                                                                                                                       ty. Simultaneously, it dynamically optimizes energy conservation and carbon reduction management measures based on the
       Conducted environmental management training with a total duration of         ?,???         hours
                                                                                                                                       inventory results, promoting the effective integration of governance requirements with all aspects of production and operation,
                                                                                                                                       and continuously enhancing its governance effectiveness in response to climate change.
       Conducted environmental management training with an average duration of        ?.??         hours per person
       Organized   ?,???          participants for environmental management training
       Organized   ???       participants for environmental protection publicity and public welfare activities
       Invested RMB ??.????                 million in environmental protection
                                                                                                                                       ?
                                                                                                                                           Scope ? refers to direct GHG emissions from sources owned or controlled by the Company, mainly including boiler combustion, vehicle exhaust, etc.;
                                                                                                                                       Scope ? refers to indirect GHG emissions from the generation of purchased and consumed external energy, such as electricity, steam, heat, and
                                                                                                                                       cooling.
                                                 Message         About              2025 Key                                                       Governance and Compliance                                      Green Operations to    Employee Development
                          About This                                                                     Sustainability                                                             Product System for Value
                                                 from the       Hapharm           Performance in                                   Special Topic   to Solidify a Foundation for                                   Advance Low-Carbon      to Build a Safe and     Appendix                 2025 Sustainability Report
                           Report                                                                        Management                                                                         Creation
                                                 Chairman        Group             Sustainability                                                         Stable Growth                                              Management              Shared Future
Strategy
         Risk type                     Speci?c description          Time horizon      Financial impact          Response measures                   Speci?c description                 Speci?c description                   Time horizon      Financial impact              Response measures
                                                                                                           Integrate extreme weather
                                                                                                                                                                                                                                                                             Align with evolving
                                                                                                           risks into operational and
                                                                                       Production                                                                                                                                                                            market demands and
                                                                                                           emergency management                                                     Emerging disease prevention
                                Extreme weather events may                             stoppage                                                                                                                                                                              business strategy,
                                                                                                           systems, enhance production                                              needs and public health
           Extreme              disrupt production sched-           Short and          losses and                                                                                                                                                Revenue growth              continuously monitor
                                                                                                           continuity safeguards and                 Emerging market                challenges driven by climate
           weather              ules and logistics arrange-         medium term        increased                                                                                                                                Long-term        and expanded                climate-related health
                                                                                                           contingency plans, and                    opportunities                  change may stimulate demand
                                ments                                                  operating costs                                                                                                                                           market share                trends, and drive a
                                                                                                           strengthen risk identi?cation                                            for related therapies and
                                                                                                                                                                                                                                                                             rational portfolio layout
                                                                                                           and response capabilities for                                            products
                                                                                                                                                                                                                                                                             of products and
Phys-                                                                                                      critical nodes
                                                                                                                                                                                                                                                                             solutions
ical
risks
                                                                                                           Enhance energy consumption
                                Rising ambient temperatures
                                                                                       Higher energy       analysis and cold chain
           Increase in          impose stricter requirements
                                                                                       costs and           operations management,
           annual               on temperature control and
                                                                    Long-term          increased           promote energy-saving                   The Company focuses on strengthening its management foundation through capacity building. In response to climate change-re-
           average              cold chain management across
                                                                                       operating           technologies and equipment              lated risks and emission reduction requirements, and in line with its production and operational realities, the Company organizes
           temperature          production, storage, and
                                                                                       expenses            optimization, and improve               relevant training to deepen the understanding of climate change topics and related compliance requirements among management
                                transportation
                                                                                                           energy ef?ciency                        personnel and employees in key positions, thereby enhancing their ability to identify and respond to climate-related risks in daily
                                                                                                                                                   management.
                                                                                                           Continuously monitor
                                                                                                           evolving climate and
                                Carbon emissions and energy
                                                                                                           environmental policies,
                                management regulations are                             Increased
                                                                                                                                                                                Participating in special topic training on energy conservation and carbon reduction to
                                progressively tightening,                              compliance
                                                                                                           integrate relevant require-                          Case            enhance low-carbon management capabilities
                                                                    Medium and                             ments into environmental
           Policy risk          subjecting the company to                              costs and
                                                                    long term                              management and business
                                heightened compliance                                  higher capital                                                      In   2025,     the     Company      organized       relevant
                                                                                                           decision-making processes,
                                obligations and management                             expenditures
                                                                                                           and proactively plan energy                     personnel to participate in a special topic
                                pressure
                                                                                                           conservation and carbon                         training on energy conservation and carbon
                                                                                                           reduction initiatives                           reduction held by the relevant departments of
                                                                                                                                                           Songbei      District,    Harbin    City,   Heilongjiang
                                                                                                            Conduct technical                              Province. The training, centered on the require-
                                                                                       Higher               assessments and phased                         ments of the "dual carbon" goals, systematically
                                Existing energy equipment
                                                                                       investment in        optimization of energy                         explained      basic      energy     theories,       energy
                                and production facilities
Tran-                                                                                  equipment            equipment and production
           Technology           face pressure to upgrade to         Medium and                                                                             consumption indicator accounting methods, and
sition                                                                                 upgrades and         facilities, implement
           risks                meet current energy                 long term                                                                              key points of carbon peak and carbon neutrality
Risk                                                                                   increased            energy-saving retro?ts
                                ef?ciency and emission                                                                                                     policies, helping participants to enhance their
                                                                                       depreciation         aligned with operational
                                standards                                                                                                                  understanding of the policy requirements and
                                                                                       expenses             realities, and enhance asset                                                                                                Special topic training on energy conservation
                                                                                                            utilization ef?ciency                          implementation paths for energy conservation                                             and carbon reduction
                                                                                                                                                           and carbon reduction.
                                                                                                            Strengthen environmental
                                Environmental governance
                                                                                                            management and disclo-
                                and climate response
                                                                                                            sure, continuously advance
                                performance attract                                    Higher
                                                                                                            energy conservation,
           Reputational         heightened attention from the       Short and          ?nancing costs                                              At the same time, the Company focuses on optimizing its energy structure in the production and operation process. It explores
                                                                                                            carbon reduction, and
           risk                 public and investors,               medium term        and reduced
                                                                                                            environmental compliance               the application of clean energy sources such as photovoltaic power generation based on its energy consumption conditions. By
                                increasing corporate                                   revenue
                                                                                                            practices, and enhance                 increasing the proportion of renewable energy source usage, it gradually reduces the emission pressure brought by traditional
                                reputation management
                                                                                                            external transparency and              energy consumption.
                                pressure
                                                                                                            management credibility
                                                  Message               About              2025 Key                                                        Governance and Compliance                                 Green Operations to   Employee Development
                            About This                                                                             Sustainability                                                         Product System for Value
                                                  from the             Hapharm           Performance in                                    Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix          2025 Sustainability Report
                             Report                                                                                Management                                                                     Creation
                                                  Chairman              Group             Sustainability                                                          Stable Growth                                         Management             Shared Future
               Case           Photovoltaic power generation project at the Second Chinese Medicine Factory                                                 Energy and Resource Management
            To reduce energy consumption intensity and GHG
            emissions during operations, the Company advanced
            the construction of a photovoltaic power generation                                                                                            Energy Utilization
            project at its Second Chinese Medicine Factory and
            connected it to the grid. Since its commissioning, the
            project has operated stably overall, and the substitution
                                                                                                                                                           In accordance with the Energy Law of the People's Republic of China, the Company has formulated and issued the Hapharm Group
            effect of clean energy has gradually become apparent.
                                                                                                                                                           Energy Management Measures, establishing a standardized energy management system. On this basis, the Company coordinates
            During the reporting period, the photovoltaic system
                                                                                                                                                           its subsidiaries to advance energy management work, implements full-process supervision, inspection, and assessment of their
            generated a total of 500,200 kWh of electricity, provid-
                                                                                                                                                           performance, guides special actions for lean energy conservation, and strengthens key matters such as internal audits of energy
            ing practical support for the Company's efforts to
                                                                                                                                                           management.
            address      climate   change   and     optimize    its   energy                    Photovoltaic panels at the Second
            structure.                                                                             Chinese Medicine Factory
                                                                                                                                                                                                              Each subsidiary of the Company has formulated energy management systems,
                                                                                                                                                                                                              which include content related to energy procurement, use, conservation, and
                                                                                                                                                                                                              evaluation.
    Impact, Risk, and Opportunity Management
The Company integrates climate change-related impacts, risks, and opportunities into a uni?ed environmental and operational
                                                                                                                                                                                                              The Company establishes energy consumption ledgers and conducts energy use
management framework, continuously conducting systematic identi?cation and dynamic management. Through energy use analy-
                                                                                                                                                                                                              analysis. The Company records and tabulates actual energy consumption daily,
sis and production operation assessments, the Company identi?es the potential impacts of factors such as extreme weather,
                                                                                                                                                                                                              performs summary analysis periodically to promptly identify anomalies in energy
temperature changes, policy tightening, and technological iteration on production operations, cost structure, and supply chain
                                                                                                                                                                                                              consumption, ?nds the causes, and formulates solutions.
stability, and conducts comprehensive evaluations based on the degree of impact and frequency of occurrence. Based on the
evaluation results, the Company continuously optimizes its energy conservation and carbon reduction management measures,
integrates relevant requirements into production operations and management decision-making processes, and strengthens
continuous control over climate-related risks through data monitoring and capacity building. While effectively preventing environ-
mental and compliance risks, the Company also focuses on new health demands and market expansion opportunities brought by                                                                                     The Company strengthens management and control by establishing energy
climate change, promoting synergy between environmental management and business development.                                                                                                                  consumption quotas for production lines. Data on energy consumption for more
                                                                                                                                                                                                              than ten eligible production lines is accumulated, quotas are established, and
                                                                                                                                                                                                              these quotas are continuously optimized based on actual usage.
Indicators and Objectives
At the current stage, the Company's carbon management focuses on Scope 1 and Scope 2 emissions and is steadily incorporating                                                                                  The Company enhances monitoring of high-consumption equipment. Metering is
Scope 3 emissions into its control system. It has already initiated the identi?cation of core emission sources, speci?cally covering                                                                          added to some high-energy-consuming equipment, a monitoring system is estab-
carbon emissions generated from employee commuting, business travel, the production of purchased raw materials, and product                                                                                   lished, data on equipment energy consumption is collected, energy use trends are
transportation processes.                                                                                                                                                                                     analyzed, and operating statuses are reasonably adjusted to ensure ef?cient
                                                                                                                                                                                                              operation.
                          Indicator name1                                       Unit                                2025 data
               Scope 1 greenhouse gas emissions                    Tonnes of CO 2 equivalent                      ??,???.??                                                                                   1.The Company strengthens energy use inspections to reduce energy waste. Daily
                                                                                                                                                                                                              inspections are conducted on the energy preparation, transmission, and distribu-
                                                                                                                                                                                                              tion systems to prevent leaks, drips, and spills, thereby reducing energy waste.
              Scope 2 greenhouse gas emissions                     Tonnes of CO 2 equivalent                     ???,???.??
                Total greenhouse gas emissions                     Tonnes of CO 2 equivalent                     ???,???.??                                                                                 The Company's energy use management measures
    The Company calculates its greenhouse gas emissions mainly in accordance with relevant standards and methodologies of the GHG Protocol, and conducts
measurement in combination with relevant national and industrial regulations.
                                           Message            About           2025 Key                                                         Governance and Compliance                                 Green Operations to   Employee Development
                     About This                                                                       Sustainability                                                          Product System for Value
                                           from the          Hapharm        Performance in                                     Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and    Appendix                2025 Sustainability Report
                      Report                                                                          Management                                                                      Creation
                                           Chairman           Group          Sustainability                                                           Stable Growth                                         Management             Shared Future
                                                                                                                                                                          Upgrading the automatic control of the heating system to reduce steam consumption and
          Case         Strengthening internal energy audit and control to solidify the foundation for energy conservation
                       and cost reduction
                                                                                                                                                           Case           increase ef?ciency
     In 2025, the Company systematically conducted
                                                                                                                                                       The original heating systems in some workshops
     internal energy audits, on-site special inspections,
                                                                                                                                                       of Harbin Pharmaceutical General Factory were
     and energy conservation awareness campaigns for
                                                                                                                                                       incapable of temperature adjustment. Constant
     its subsidiary production enterprises. Weaknesses
                                                                                                                                                       heating was still maintained during non-produc-
     in    energy    management        were     identi?ed   and
                                                                                                                                                       tion hours at night, resulting in energy waste. In
     addressed, resulting in a total of 35 energy-saving
     improvement recommendations being issued. In
                                                                                                                                                       control system, which can automatically adjust
     October of the same year, the Company held a
                                                                                                                                                       heating parameters according to preset tempera-
     special meeting on energy management. Through a
                                                                                                                                                       tures and time periods, thus effectively improving
     systematic review of the effectiveness and short-
                                                                                                                                                       energy utilization ef?ciency. According to estima-
     comings of the internal audit work and specialized                                                                                                                                                                           Addition of an automatic control system for the
                                                                                                                                                       tion, the renovation will reduce annual heating
                                                                                                                                                                                                                                               heat exchange station
     training sharing practical ideas for energy-saving
                                                                                                                                                       steam consumption by approximately 540 tons.
     renovation projects, the Company comprehensively                               Energy internal audit training
     enhanced its level of re?ned energy management,
     helping to achieve the strategic goals of energy
     conservation,      cost      reduction,   and    ef?ciency
     improvement.
                                                                                                                                               Green Of?ce
                                                                                                                                               The Company continuously promotes green of?ce management in its daily operations. By advocating paperless of?ces, online
                       Upgrading drying equipment heaters to achieve dual improvements in energy ef?ciency and
          Case         production capacity                                                                                                     meetings, conservation of electricity and water, and recycling of of?ce supplies, it reduces resource consumption and unneces-
                                                                                                                                               sary energy waste. At the same time, considering the operational characteristics of its of?ce spaces, the Company explores the
     In    January   2025,     Shiyitang   Chinese    Medicine                                                                                 application of energy-saving technologies in of?ce buildings while ensuring a comfortable and stable working environment, gradu-
     completed the upgrade and renovation of its ?uid                                                                                          ally improving the energy utilization ef?ciency of its of?ce operations.
     bed dryer heater. Following the renovation, the
     drying ef?ciency of the equipment was signi?cantly
     improved; the single-batch operating time of the
     ?uid bed dryer in the drug granulation process is
     expected to be reduced by two hours, achieving the
     dual goals of enhancing energy ef?ciency and
                                                                                                                                                           Case           Green operation practices for of?ce buildings
     increasing production ef?ciency. This renovation
     effectively improved equipment operating ef?ciency                                                                                                To respond to national energy conservation and emission reduc-
     and    reduced     production     energy    consumption.                                                                                          tion policies and improve the heating ef?ciency of its of?ce
     During the reporting period, it saved a cumulative                                                                                                building, the Company implemented a smart heating energy-sav-
                                                                       Upgrading and renovation of the ?uid bed dryer heater
     total of 23,000 kWh of electricity and 76.8 tonnes                                                                                                ing renovation project, piloting it at its headquarters of?ce
     of steam, accumulating practical experience for the                                                                                               building and associated heat exchange station. The project
     Company's future energy-saving optimizations in                                                                                                   achieved re?ned management and dynamic adjustment of heating
     production processes.                                                                                                                             operations through measures such as independent operation
                                                                                                                                                       renovation of the heating system, optimization of the secondary
                                                                                                                                                       pipe network, online monitoring of indoor temperatures, and
                                                                                                                                                       upgrading of heat metering methods. This effectively improved
                                                                                                                                                       heating quality and avoided energy waste. Since the project's
                                                                                                                                                       completion and stable operation, it has saved approximately 150
                                                                                                                                                       tonnes of standard coal annually, reduced carbon dioxide
                                                                                                                                                       emissions by about 540 tonnes, and simultaneously lowered
                                                                                                                                                       emissions of nitrogen oxides, sulfur dioxide, and particulate                        Smart heating energy-saving
                                                                                                                                                       matter, playing a positive role in mitigating climate change and                         renovation project
                                                                                                                                                       improving regional environmental quality.
                                      Message            About               2025 Key                                                              Governance and Compliance                                 Green Operations to    Employee Development
                  About This                                                                          Sustainability                                                              Product System for Value
                                      from the          Hapharm            Performance in                                          Special Topic   to Solidify a Foundation for                              Advance Low-Carbon      to Build a Safe and   Appendix         2025 Sustainability Report
                   Report                                                                             Management                                                                          Creation
                                      Chairman           Group              Sustainability                                                                Stable Growth                                         Management              Shared Future
       Case          Practicing the concept of green travel and deepening energy conservation and                                                  Water Resource Utilization
                     emission reduction practices
     In January 2025, in response to the national policy orientation of                                                                            The Company strictly adheres to relevant national and local laws, regulations, and policies, systematically promoting the re?ned
     energy conservation and emission reduction, and in light of the                                                                               management of water resources. Upholding the principles of scienti?c management and continuous improvement, the Company
     operational demands of cost reduction and ef?ciency improve-                                                                                  focuses on the core goals of ef?cient and intensive use of water resources, cost reduction, and ef?ciency improvement. By
     ment, the Company of?cially launched the special program for the                                                                              strengthening control measures throughout the entire water usage process, it achieves the dual effects of resource protection and
     new energy replacement of of?cial vehicles. The Company                                                                                       waste elimination.
     replaced 11 fuel vehicles approaching the end of their service life
     under itself and 9 af?liated enterprises with domestic hybrid                                                                                 The Company strengthens the daily operation, maintenance, and control of water-using equipment, conducting targeted inspec-
     models. The carbon emission per vehicle decreased by approxi-                                                                                 tions and rectifying problems to reduce water resource waste from leaks, drips, and spills. In its production and operation process-
     mately 40% year-on-year, which effectively facilitated the enter-              The Company's new energy of?cial vehicles                      es, the Company utilizes a circulating water system, achieving the dual goals of reducing water consumption and improving utiliza-
     prise’s green and low-carbon transformation process, and                                                                                      tion ef?ciency through optimized water resource allocation. Additionally, on the annual environmental protection and water
     accumulated replicable and generalizable practical experience for                                                                             conservation day, the Company conducts water-saving publicity and education in various forms to raise employee awareness,
     the Company to achieve its dual carbon goals.                                                                                                 laying a solid foundation for building a water-saving enterprise and promoting corporate sustainability.
        Key performance
                                                                                                                                                                Key performance
         Category                                Indicator                                    Unit                     2025 data
                                                                                                                                                                          Indicator name                                    Unit                               2025 data
                                        Direct energy consumption                Tonnes of standard coal               15,778.58
                                                                                                                                                                     Total water consumption                               Tonnes                              6,320,252
                                           Gasoline consumption                              Tonnes                      116.71
                                            Diesel consumption                               Tonnes                      84.84                                       Freshwater consumption                                Tonnes                               1,074,961
                                         Natural Gas Consumption               10 Thousand Cubic Meters                 1,164.15
                                                                                                                                                                   Recycled water consumption                              Tonnes                              11,454,932
         Energy                         Indirect energy consumption              Tonnes of standard coal               31,201.88
         usage                                                                                                                                                     Water consumption intensity
                                                                                                                                                                      per million in revenue                 Tonnes/RMB 1 million in revenue                     395.91
                                           Purchased electricity                             MWh                       58,192.01
                                             Purchased Steam                                  GJ                       704,867.68
                                         Total energy consumption                Tonnes of standard coal               46,980.46
                                  Comprehensive energy consumption per              Tonnes of standard
                                            unit of revenue                            coal/million                       2.94
                                      Total clean energy consumption                Tonnes of standard
                                         (photovoltaic, natural gas)                       coal                        16,070.24
         Clean                    Solar energy consumption (photovoltaic)                    MWh                        4,784.65
         energy
                           Proportion of clean energy consumption to total energy              %                         34.21
                                                consumption
                                        Message           About               2025 Key                                                       Governance and Compliance                                 Green Operations to   Employee Development
                    About This                                                                         Sustainability                                                       Product System for Value
                                        from the         Hapharm            Performance in                                   Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix            2025 Sustainability Report
                     Report                                                                            Management                                                                   Creation
                                        Chairman          Group              Sustainability                                                         Stable Growth                                         Management             Shared Future
Pollutant Emissions                                                                                                                          Exhaust Gas Management
                                                                                                                                             As a pharmaceutical enterprise committed to environmental responsibility, the Company strictly complies with core regulations
Wastewater Management                                                                                                                        such as the Environmental Protection Law of the People's Republic of China and the Air Pollution Prevention and Control Law of
                                                                                                                                             the People's Republic of China, systematically advancing waste gas management. The Company's waste gas primarily consists of
                                                                                                                                             process emissions originating from basic production steps such as crushing and packaging, as well as core processes including
The Company strictly adheres to the requirements of laws and regulations such as the Environmental Protection Law of the                     active pharmaceutical ingredient synthesis and solvent recovery. Its characteristic pollutants are mainly particulate matter and
People's Republic of China and the Water Pollution Prevention and Control Law of the People's Republic of China to carry out                 volatile organic compounds.
full-process wastewater management. Each subsidiary is equipped with a standardized wastewater treatment station and profes-
sional technicians dedicated to process parameter control and system operation management, ensuring that treated wastewater
meets discharge standards consistently. The management of production wastewater fully implements the core control principle of
"separating clean water from wastewater, treating wastewater based on its quality, and ensuring compliant discharge."                                         Key performance
                                                                                                                                                                        Indicator name                                   Unit                            2025 data
          Case         Building a standardized sewage station to control emissions and treat pollution
                                                                                                                                                                       Total waste gas                              Cubic meter                           21,560.51
       Sanchine has constructed its own wastewater treatment station with
       a daily capacity of 3,200 tonnes, utilizing the sequencing batch
       reactor (SBR) activated sludge process for wastewater pretreatment.                                                                                        Particulate matter (PM)                              Tonnes                                  2.55
       The treated ef?uent quality consistently meets the requirements of
       the Discharge Standard of Water Pollutants for Pharmaceutical
       Industry Mixing/Compounding and Formulation Category before                                                                                                   Sulfur oxides (SOx)                               Tonnes                                  0.48
       being discharged into municipal sewage treatment plants via the
       municipal pipe network. Sanchine strictly adheres to technical speci-                                                                                       Nitrogen oxides (NOx)                               Tonnes                                  18.82
       ?cations in con?guring and upgrading online wastewater monitoring
       facilities, while also commissioning third-party professional monitor-
                                                                                              Wastewater treatment station                                 Volatile organic compounds (VOCs)                           Tonnes                                  172.61
       ing agencies to conduct regular testing of wastewater pollutants at
       the plant boundary. By real-time monitoring of discharge data,
       precise control of pollution control facility operations, and continu-
       ous optimization of treatment processes, the Company enhances the
       effectiveness of its pollution control efforts.
                                                                                                                                             Noise Management
             Key performance
                                                                                                                                             The Company strictly adheres to the relevant requirements of the Law of the People's Republic of China on the Prevention and
                                                                                                                                             Control of Noise Pollution to implement noise control measures, upholding the governance principle of "source control and
                          Indicator name                            Unit                                 2025 data
                                                                                                                                             transmission path sound insulation." In equipment selection, priority is given to low-noise facilities to minimize noise generation
                                                                                                                                             at the source. For high-noise equipment such as air compressors and fans, independent soundproof rooms are provided. Produc-
             Total amount of wastewater discharge                  Tonnes                                1,052,611                           tion pipelines are treated with ?exible connections and sound-insulating wrapping to reduce noise transmission. Additionally,
                                                                                                                                             green belts are planted along the plant boundaries to create natural noise barriers. Through these targeted control measures, the
                                                                                                                                             Company effectively implements noise governance requirements, ensuring harmonious coexistence between the production
                Chemical oxygen demand (COD)                       Tonnes                                   38.86
                                                                                                                                             environment and the surrounding area.
                   Ammonia nitrogen (NH?-N)                        Tonnes                                    1.28
                                         Message            About             2025 Key                                                 Governance and Compliance                                      Green Operations to    Employee Development
                       About This                                                                     Sustainability                                                    Product System for Value
                                         from the          Hapharm          Performance in                             Special Topic   to Solidify a Foundation for                                   Advance Low-Carbon      to Build a Safe and   Appendix           2025 Sustainability Report
                        Report                                                                        Management                                                                Creation
                                         Chairman           Group            Sustainability                                                   Stable Growth                                              Management              Shared Future
Waste Management                                                                                                                                                      Classi?ed                              Standardized                               Compliant
                                                                                                                                                                      storage                                transportation                             disposal
The Company strictly complies with regulations such as the Law of the People's Republic of China on the Prevention and Control
of Environmental Pollution by Solid Waste and the Regulations on the Management of Municipal Solid Waste to carry out waste
management. Aligning with the characteristics of the pharmaceutical sector, it also implements the requirements of the Measures
                                                                                                                                                            Strict implementation                        Internal transporta-                  Recyclable waste is
for the Administration of Hazardous Waste Transfer. Guided by the core policy of "reduction, resource recovery, and harmless
                                                                                                                                                            of zoned and                                 tion utilizes dedicat-                processed by
disposal," the Company has established a tiered management system encompassing "source reduction—recycling—end-of-pipe
                                                                                                                                                            classi?ed storage                            ed sealed containers                  compliant renewable
harmless disposal" and implemented a standardized closed-loop process of "classi?ed storage—standardized transportation—
                                                                                                                                                            management                                   and transport                         resource units, while
compliant disposal."
                                                                                                                                                            speci?cations is                             vehicles, while                       non-recyclable
                                                                                                                                                            carried out, ful?lling                       external transporta-                  hazardous waste is
                                                                                                                                                            the "four prevention"                        tion of hazardous                     disposed of
 Reduction                                                                                                                                                  requirements of                              waste is entirely                     harmlessly in
 measures                By optimizing processes to improve packaging ef?ciency and reduce material loss, the generation of
                                                                                                                                                            anti-seepage,                                entrusted to units                    accordance with laws
                         waste and discarded packaging materials is minimized at the source.
                                                                                                                                                            anti-loss, anti-disper-                      possessing road                       and regulations.
                                                                                                                                                            sion, and rain                               transport permits and
                                                                                                                                                            protection, while                            hazardous waste
                                                                                                                                                            simultaneously                               disposal quali?ca-
 Resource                                                                                                                                                   equipping emergency                          tions;
 recovery and            For high-concentration waste solvents, priority is given to recovery and puri?cation through processes                             material reserves;
 utilization
                         such as distillation and recti?cation, followed by reuse in production processes to reduce hazardous
                         waste generation.                                                                                                                                                         The Company's waste disposal process
                                                                                                                                       General Waste Management
 Harmless
 disposal                Non-recyclable hazardous waste is managed by category according to its hazardous characteristics
                         and entrusted to quali?ed professional institutions for harmless disposal.                                    The Company's general waste mainly includes domestic waste generated by employees, of?ce paper waste, used packaging
                                                                                                                                       materials, and food waste. The Company implements classi?ed collection and standardized storage for general waste, entrusting
                                                                                                                                       legally quali?ed third-party units for removal and disposal to ensure that the disposal process is compliant, safe, and orderly. At
                                                                                                                                       the same time, by promoting continuous ?ow production and optimizing production organization methods, the generation of
                                               The Company's waste management policy
                                                                                                                                       general waste and pollutants is reduced.
                                                                                                                                       Hazardous and Medical Waste Management
                                                                                                                                       The Company's hazardous waste mainly includes laboratory waste liquid, waste ion exchange resins, non-conforming products,
                                                                                                                                       and laboratory waste. All types of hazardous waste are strictly managed by category in accordance with the National Catalogue of
                                                                                                                                       Hazardous Wastes and incorporated into the uni?ed hazardous waste management system according to pharmaceutical industry
                                                                                                                                       hazard categories (e.g., HW02, HW49).
                                                                                                                                       The Company implements the principle of "strict management" for hazardous waste, clarifying the responsibility requirement of
                                                                                                                                       "who pollutes, who treats." Through systems such as the Environmental Protection Management Measures, Hazardous Waste
                                                                                                                                       Management Measures, and Emergency Response Plan for Environmental Emergencies, the Company standardizes the manage-
                                                                                                                                       ment of the entire process of hazardous waste generation, collection, storage, transfer, and disposal.
                                         Message            About              2025 Key                                                  Governance and Compliance                                 Green Operations to     Employee Development
                     About This                                                                       Sustainability                                                    Product System for Value
                                         from the          Hapharm           Performance in                              Special Topic   to Solidify a Foundation for                              Advance Low-Carbon       to Build a Safe and   Appendix               2025 Sustainability Report
                      Report                                                                          Management                                                                Creation
                                         Chairman           Group             Sustainability                                                    Stable Growth                                         Management               Shared Future
     Speci?c operational procedures include:                                                                                                             Key performance
     Hazardous waste is centrally collected in the production system and quality inspection workshops and then transferred to
     the temporary hazardous waste storage room;
     The temporary storage room is constructed in accordance with the Standard for Pollution Control on Hazardous Waste                                           Indicator name                                         Unit                                2025 data
     Storage and implements classi?ed management with clear and conspicuous hazard signage;
     For off-site disposal, all hazardous waste is entrusted to professional units holding a Hazardous Waste Operation License                                Total hazardous waste                                  Tonnes                                   210.46
     to complete reception and compliant disposal within a ?xed timeframe.
                                                                                                                                                           Hazardous waste intensity                   Tonnes/RMB 1 million in revenue                         0.01
                                                                                                                                                           Total non-hazardous waste                                 Tonnes                                  2,075.38
To ensure employee safety, the Company requires strict adherence to personal protective equipment requirements during the
                                                                                                                                                        Non-hazardous waste intensity                  Tonnes/RMB 1 million in revenue                         0.13
sorting, transfer, and temporary storage of hazardous waste. Additionally, designated positions, ?xed schedules, and de?ned
routes are implemented to minimize secondary pollution and safety risks.
                                                                                                                                                               Waste recycling rate                                       %                                    91.42
           During the reporting period, the Company
                                    ???
         During the reporting period,           % of the waste generated by the Company was disposed of in compliance
         with regulations, with   no incidents                       of illegal discharge or transfer occurring.
                                                                                                                                         Ecosystem and Biodiversity Conservation
                                                                                                                                         The Company places high importance on the interrelationship between raw material sources, production activities, and the natural
                                                                                                                                         ecological environment. While complying with national laws and regulations on ecological and environmental protection, the
                                                                                                                                         Company continuously identi?es potential impacts of its business activities on ecosystems and biological resources. It prudently
                                                                                                                                         advances risk prevention, control, and management related to biodiversity, striving to reduce adverse environmental impacts while
                                                                                                                                         ensuring stable production and operation.
           Case         Closed-loop reclamation of organic solvents to improve quality and ef?ciency in resource utilization
                                                                                                                                         The Company integrates ecological and environmental protection concepts into its planting and management processes. By
                                                                                                                                         regularly monitoring and assessing soil conditions in planting areas and tracking changes in soil physicochemical indicators, the
        In the synthesis workshop, organic solvents are prioritized for
                                                                                                                                         Company prevents potential impacts on soil ecology caused by improper planting or input usage, promoting the coordinated
        cooling, circulation, and reuse within the production process.
                                                                                                                                         development of Chinese materia medica production and the local ecological environment.
        When concentrations fall below usage standards, they are
        transported via pipelines to the solvent reclamation workshop
        for puri?cation before being returned for reuse. The solvent
        reclamation workshop primarily handles the reclamation of
        various organic solvents from the synthesis workshop and the
        sterile API workshop, with main products being reclaimed
        anhydrous ethanol and industrial ethanol. For other organic
        solvents reclaimed from the synthesis workshop, the Sanjing
        Mingshui workshop periodically conducts negative pressure
        distillation and reclamation in a multi-functional tower. Quali?ed
        products are sent to ?nished product tanks, while non-conform-
        ing products are temporarily stored in intermediate tanks for
                                                                                          Solvent reclamation workshop
        reprocessing. This entire process maximizes resource utiliza-
        tion, minimizes losses, and ensures the quality of reclaimed
        products. Throughout the year, a total of 50 tonnes of ethanol
        and 10 tonnes of ethylene glycol were saved.
Employee Development
   to Build a Safe and
        Shared Future
       The content of this chapter
       Employee Rights and Care              ??
       Talent Cultivation and Development    ??
       Occupational Health and Safety        ??
       Rural Revitalization Practices       ???
       Public Welfare and Social Action     ???
                                              Message              About              2025 Key                                                         Governance and Compliance                                    Green Operations to   Employee Development
                         About This                                                                           Sustainability                                                             Product System for Value
                                              from the            Hapharm           Performance in                                     Special Topic   to Solidify a Foundation for                                 Advance Low-Carbon     to Build a Safe and      Appendix                 2025 Sustainability Report
                          Report                                                                              Management                                                                         Creation
                                              Chairman             Group             Sustainability                                                           Stable Growth                                            Management             Shared Future
                                                                                                                                                         Opportunity type                      Speci?c description                 Time horizon    Financial impact                Response measures
Employee Risks and Opportunities                                                                                                                                                      A comprehensive human resource                                                           Continuously optimize the
                                                                                                                                                                                      management system has been                                                               human resource manage-
                                                                                                                                                                                      established. Through measures such                                                       ment system, improve
Focusing on employee team stability and organizational sustainability goals, the Company systematically identi?es and assesses                                                        as strengthening institutional                                                           career paths, build a
employee-related risks and opportunities, integrating management requirements into human resources management and daily                                                               guarantees, deepening training and                                                       full-cycle training system
                                                                                                                                                                                      development, and optimizing                                                              and a fair and reasonable
operational processes. In conjunction with business development plans and the actual workforce situation, the Company continu-                                      Talent                                                        Medium and
                                                                                                                                                                                      compensation and incentives, the                                                         compensation system,
ously evaluates the potential impacts of factors such as talent mobility, person-job ?t, and occupational health, implementing                                      retention                                                     long term
                                                                                                                                                                                      Company aims to achieve sustainable                                                      empower sustainable talent
dynamic monitoring and response through existing management mechanisms.
                                                                                                                                                                                      talent career development, reduce the                                                    development, and solidify
                                                                                                                                                                                      turnover rate of core talent, and                                                        the foundation for talent
                                                                                                                                                                                      ensure the inheritance of organiza-                                                      retention.
                                                                                                                                                                                                                                                     Reduced
                                                                                                                                                                                      tional experience and the continuous,
        Risk type                     Speci?c description               Time horizon          Financial impact           Response measures             Employ-                                                                                       recruitment
                                                                                                                                                                                      stable development of the business.                                                      Strengthen promotion and
                                                                                                                                                       ment                                                                                          and training
                                                                                                                        Deepen school-enter-                                                                                                                                   publicity of the employer
                                                                                                                                                       oppor-                                                                                        costs and
                            In?uenced by objective factors such as                                                      prise cooperation to                                                                                                                                   brand, fully showcase the
                                                                                                                                                       tunities                                                                                      improved labor
                            Harbin's geographical location and                                                          broaden channels for                                          Through standardized employment                                                          Company's compliant
                                                                                                                                                                                                                                                     ef?ciency
                            regional economic development levels,                                                       talent attraction and                                         practices and caring initiatives, the                                                    employment practices and
                                                                                             Rising labor                                                           Employer
           Regional         some high-quality talent exhibits lower                                                     cultivation; strengthen                                       Company continuously enhances its                                                        employee care initiatives,
Employ-                                                                                      costs and                                                              brand                                                         Medium and
           recruitment      job-seeking willingness, leading to        Short and                                        employer brand building                                       employer brand in?uence and market                                                       actively participate in
ment                                                                                         declining                                                              enhance-                                                      long term
           disadvantag-     certain recruitment pressures for the      medium term                                      by highlighting the                                           reputation, attracting high-quality                                                      industry employer brand
risks                                                                                        workforce                                                              ment
           es               Company and constraining the                                                                Company's develop-                                            talent and creating a positive talent                                                    awards, and continuously
                                                                                             productivity
                            ef?ciency and progress of personnel                                                         ment platform and                                             siphon effect.                                                                           enhance brand in?uence
                            replenishment.                                                                              career stability to                                                                                                                                    and reputation.
                                                                                                                        continuously enhance
                                                                                                                        talent attraction.                                                                                                                                     Open up professional
                                                                                                                                                                                      Clear and smooth career development
                                                                                                                                                                                                                                                                               promotion channels for
                                                                                                                                                                                      paths are established, and diversi?ed
                            Examples include ?re and                                                                                                                                                                                                                           R&D personnel, establish
                                                                                                                                                                                      incentive mechanisms are improved to
                            explosion risks associated with                                                                                                                                                                                                                    innovation incentives and
           Fire and                                                    Short and                                                                                    Stimula-          fully stimulate employee innovative                            Revenue growth
                            chemicals, as well as ?re hazards                                                                                          Talent                                                                                                                  special awards, encourage
           explosion                                                   medium term                                                                                  tion of           vitality and creative enthusiasm.           Medium and         and enhanced
                            arising from the indoor storage of                                                                                         cultiva-                                                                                                                employees to participate in
                                                                                                                                                                    innovative        Technological breakthroughs and             long term          workforce
                            diesel generators.                                                                                                         tion                                                                                                                    challenging projects and
                                                                                                                                                                    vitality          management innovation are promoted                             productivity
                                                                                                                                                                                                                                                                               cross-departmental
                                                                                             Increased asset            Strengthen control                                            to continuously enhance the
                                                                                                                                                                                                                                                                               collaboration, and foster a
                                                                                             losses, production         over ?re safety,                                              Company's core competitiveness.
                            Examples include distribution boxes                                                                                                                                                                                                                positive and upward-look-
                                                                                             stoppage losses,           mechanical
Safety     Electric         in the water supply pump room of           Short and                                                                                                                                                                                               ing innovation culture.
                                                                                             compensation               equipment safety
risks      shock            the power workshop, which may              medium term
                                                                                             expenses, and              devices, and                                                                                                                                           Implement annual
                            cause electric shock injuries.
                                                                                             emergency                  personnel safety                                                                                                                                       employee physical
                                                                                             response costs             behaviors.                                                    The working environment and                                                              examinations and
                                                                                                                                                                                      occupational health management are                                                       occupational health
                                                                                                                                                                                      continuously optimized to effectively                                                    monitoring, optimize labor
                                                                                                                                                       Health      Employee                                                                          Lower medical
                                                                                                                                                                                      protect the physical and mental health      Medium and                                   protection equipment, and
                            Examples include risks of mechani-                                                                                         protec-     health                                                                            and absentee-
           Mechanical                                                  Medium and                                                                                                     of employees, reduce sick leave             long term                                    establish caring facilities
                            cal injury in production packaging                                                                                         tion        protection                                                                        ism costs
           injury                                                      long term                                                                                                      absentee rates, and further enhance                                                      such as mother-and-baby
                            and maintenance positions.                                                                                                                                employee loyalty and work engage-                                                        rooms and ?tness activity
                                                                                                                                                                                      ment.                                                                                    areas to promote humanis-
                                                                                                                                                                                                                                                                               tic care-based safety
                                                                                                                                                                                                                                                                               management.
           Dust and         Dust hazards may be generated
                                                                       Short and
           chemical         during sub-packaging in                                                                     Strengthen control
                                                                       medium term           Higher medical
Occu-      hazards          production workshops.
                                                                                             expenses, reduced          over equipment and
pational
                                                                                             workforce produc-          facility sealing and
health
                                                                                             tivity, and increased      personnel protection
risks                       Noise hazards may be generated
                                                                       Short and             related                    management.
           Noise            by air conditioning systems in
                                                                       medium term
                            production workshops.
                                        Message             About              2025 Key                                                   Governance and Compliance                                 Green Operations to      Employee Development
                     About This                                                                     Sustainability                                                       Product System for Value
                                        from the           Hapharm           Performance in                               Special Topic   to Solidify a Foundation for                              Advance Low-Carbon        to Build a Safe and   Appendix     2025 Sustainability Report
                      Report                                                                        Management                                                                   Creation
                                        Chairman            Group             Sustainability                                                     Stable Growth                                         Management                Shared Future
                                                                                                                                          The Company has established a comprehensive compensation and performance grievance mechanism, clearly de?ning channels,
Employee Rights and Care                                                                                                                  procedures, and time limits to protect the legitimate rights and interests of employees. Regarding compensation, employees may
                                                                                                                                          ?le a grievance within 30 days of the salary payment date if they have objections. For performance, employees may submit a
                                                                                                                                          grievance application to the Performance Management Of?ce within ?ve working days after the announcement of assessment
                                                                                                                                          results, which will investigate and rule accordingly. Grievance channels include of?ine feedback, email systems, and union
The Company strictly complies with national laws and regulations such as the Labour Law of the People's Republic of China and             channels, ensuring that employee concerns are handled in a timely and fair manner.
the Labor Contract Law of the People's Republic of China, adhering to the principles of legal employment and standardized
management, and resolutely prohibits the use of child labor and forced labor. The Company has established a comprehensive
human resource management system, including the Internal Competition Management Measures, Compensation Management                                                    Employees may typically exercise their right to appeal through channels such as of?ine feedback, email
Measures, Employee Transfer Management Measures, and Employee Reward and Punishment Management Regulations, to                                                       systems, and cloud mailboxes in accordance with regulations. Of?ine feedback is generally directed directly
effectively protect the legitimate rights and interests of employees and ?rmly prevent all types of illegal and non-compliant                Adminis-                to the Human Resources Department, which investigates, handles, and responds. If there are objections to
employment practices.                                                                                                                        trative                 the of?ine handling results, further appeals may be submitted via the Company email system or cloud
                                                                                                                                             channels                mailbox. The cloud mailbox is managed and supervised by the President's Of?ce, with handling results and
The Company has established a diversi?ed and standardized recruitment process to attract outstanding talent from various
                                                                                                                                                                     feedback reported to company management to ensure timely and effective resolution of employee appeals.
backgrounds. It fully considers the diverse backgrounds of candidates, using abilities, experience, and skills as core evaluation
criteria during selection, eliminating all forms of discrimination based on gender, age, marital status, etc., to ensure fairness and
impartiality in recruitment. The Company strictly prohibits inappropriate behaviors such as verbal abuse and harassment and
imposes corresponding penalties based on the severity of violations, aiming to create a positive working atmosphere for employ-
ees.                                                                                                                                         Trade                   Employees may ?le complaints with the trade union. If the trade union veri?es that the Company has
                                                                                                                                             union                   infringed upon employees' labor rights and interests, it has the right to legally demand corrections and
The Company continuously optimizes its recruitment management system, establishing a channel strategy of "internal recruitment               channels                assume corresponding responsibilities.
as the mainstay and external recruitment as supplementary." Talent quality assessment standards have been set, screening
resumes based on factors such as age, education, corporate system experience, and career stability. Interviews are evaluated
across four dimensions: company benchmarking, competency benchmarking, motivation benchmarking, and cultural benchmark-
ing, ensuring strict control over talent quality. Campus recruitment quality is rigorously controlled by assessing education, institu-
                                                                                                                                                                     In accordance with government requirements, the Company has established a dedicated department for
tion, major, and political af?liation. Background checks conducted through third-party agencies mitigate hiring risks at the source,
                                                                                                                                                                     employee rights protection. Employee appeals can be accepted and ?led through this department, which
comprehensively improving recruitment quality. In 2025, the Company recruited 794 external talents, including 115 management                 Other
                                                                                                                                                                     urges relevant responsible departments to issue responses in accordance with regulations and facilitates
trainees, achieving a notable improvement in talent quality. Among them, 68.7% were from top-tier universities (985/211), repre-             channels
                                                                                                                                                                     review by superior competent authorities, ensuring that reasonable employee demands are properly
senting a year-on-year increase of 32.1%; 61.7% held master's or doctoral degrees, a year-on-year increase of 16.2%; and 29.6%
                                                                                                                                                                     resolved.
were Party members, a year-on-year increase of 13.2%. The overall talent structure continued to be optimized.
                                                                                                                                                                                        Employee compensation and performance grievance channels
Compensation and Performance Management
                                                                                                                                          In democratic management, the Company widely solicits employee opinions through channels such as the Employee Representa-
                                                                                                                                          tive Congress and employee representative proposals. It carries out democratic management practices that are rich in content,
                                                                                                                                          distinctive in character, and diverse in form, effectively safeguarding employees' rights to know, participate, and supervise.
In terms of leave and compensation management, the Company strictly complies with laws and regulations such as the Regula-
tions on Paid Annual Leave for Employees and the Measures for the Implementation of Paid Annual Leave for Enterprise Employ-
ees, ensuring that employee working hours meet legal requirements and safeguarding their right to rest and take leave. The
Company has formulated a uni?ed compensation management system to standardize salary distribution and incentive manage-
ment for headquarters and subsidiaries. It has optimized the compensation structure by implementing a "broadband compensa-
tion" model, reinforcing the incentive orientation of "paying for position value and paying for ability and performance." The Compa-
ny scienti?cally conducts job value assessments, optimizes the job value map, and clari?es career development paths for employ-
ees in both management and professional sequences. Within the salary bands, employee compensation is adjusted based on
comprehensive performance evaluation results, fully re?ecting differences in employee capabilities and performance contribu-
tions, thereby building a fair and reasonable compensation system.
                                                                                                                                                                                                         Employee Care Activities
                                               Message              About                 2025 Key                                                         Governance and Compliance                                   Green Operations to     Employee Development
                        About This                                                                                 Sustainability                                                          Product System for Value
                                               from the            Hapharm              Performance in                                     Special Topic   to Solidify a Foundation for                                Advance Low-Carbon       to Build a Safe and    Appendix                2025 Sustainability Report
                         Report                                                                                    Management                                                                      Creation
                                               Chairman             Group                Sustainability                                                           Stable Growth                                           Management               Shared Future
                                                                                                                                                           Each year, the Company conducts an administrative service
Care and Bene?ts                                                                                                                                           satisfaction survey for all employees. The questionnaire is
                                                                                                                                                           designed around seven key dimensions: property manage-
                                                                                                                                                           ment, catering, sanitation, meetings, shuttle buses, of?cial
In terms of employee care, the Company has developed diverse heart-                                                                                        vehicles, and security. The effective response rate reached
warming initiatives to meet the differentiated needs of different groups.                                                                                  98%, and the average employee satisfaction with these
For female employees, a series of activities was organized for Interna-                                                                                    service areas reached 93%, re?ecting the Company's contin-
tional Women's Day, including a corporate culture knowledge quiz, a                                                                                        uous optimization of administrative service quality.
female employee photo contest, a visit to the Hayaoliu Print Museum,
distribution of product discount coupons, and a "Rose and Book                                                                                             The Company actively carries out a promotion month for
Fragrance" reading event. "Lilac" demonstration classes for female                                                                                         factory affairs transparency and democratic management,
employees, covering embroidery, tie-dye, and gourd pyrography, were                                                                                        publicizing related knowledge through forms such as knowl-
opened    to   enrich    their    spiritual   and   cultural   lives.   Additionally,                                                                      edge competitions and employee representative training,
mother-and-baby rooms were constructed to provide comfortable resting                                                                                      thereby     strengthening      the    foundation     for   democratic
                                                                                                                                                                                                                                                               Sta? Team Building Activities
and nursing spaces for breastfeeding female employees. For employees                                                                                       management.
facing dif?culties, regular support activities such as holiday visits,                                    Outstanding Female Workers Award in
                                                                                                                 HPGF Safety Training
assistance for major illnesses, and care for children are carried out to
convey corporate warmth and enhance employees' sense of belonging.
The Company has established a comprehensive employee bene?t system                                                                                                     Key performance
covering statutory bene?ts and company bene?ts. Statutory bene?ts are
strictly implemented in compliance with laws and regulations, including
social insurance, housing provident fund, and other statutory welfare                                                                                                                     Indicator name                                     Unit                           2025 data
policies, forming a solid baseline for protecting employee rights. Compa-
ny bene?ts encompass three categories: basic protection, special                                                                                                                    Total number of employees                            Persons                              10,039
supplements, and special care. In 2025, the Company further deepened
                                                                                                                                                                                            By gender
bene?t practices by reaching group purchasing agreements with external
partners, adding high-quality and cost-effective services such as refuel-                                                                                                         Number of female employees                             Persons                               4,922
ing and insurance, enriching bene?t offerings, and effectively enhancing
                                                                                                              HPS Women's Day Activities
employees' sense of gain.                                                                                                                                                          Number of male employees                              Persons                               5,117
                                                                                                                                                                                                By age
       Bene?t type                                                            Content covered                                                                              Number of employees aged 30 and below                         Persons                                995
                                                                                                                                                                              Number of employees aged 31 to 40                          Persons                               3,427
                                 Social insurance and housing provident fund: In compliance with laws and regulations, pension                                                Number of employees aged 41 to 50                          Persons                               3,926
                                 insurance, medical insurance (including maternity insurance), unemployment insurance, work-related
                                 injury or ill health insurance, and housing provident fund are paid for employees, and relevant                                           Number of employees aged 51 and above                         Persons                               1,691
     Statutory bene?ts           regulations of the state and local governments where the Company and its subsidiaries are located
                                 regarding social insurance and housing provident fund are strictly implemented.                                                                Number of newly hired employees                          Persons                                794
                                 Bene?t policies: National and local employee bene?t policies are fully implemented, and relevant                                           Number of newly hired female employees                       Persons                                428
                                 requirements such as employee leave and bene?ts for single-child families are strictly enforced.
                                                                                                                                                                              Number of ethnic minority employees                        Persons                                393
                                                                                                                                                                             Number of employees with disabilities                       Persons                                160
                                 Basic bene?ts: These include in-kind holiday bene?ts, annual physical examinations, commuting
                                 support, free lunches, and employee team-building activities.                                                                                        Employee turnover rate                                  %                                   6
                                 Special bene?ts: Based on the Company's actual situation and job characteristics, supplementary                                                 Employee bene?t coverage rate                                %                                 100
     Company bene?ts             insurance, rental subsidies for off-site work, tea break snacks, ?tness and entertainment facilities,
                                 and low-price group purchases are provided.                                                                                              Employee satisfaction survey coverage rate                          %                                 100
                                 Special care bene?ts: Exclusive bene?ts such as mother-and-baby rooms are established to meet                                                Employee trade union coverage rate                              %                                 100
                                 the needs of speci?c employee groups.
                                        Message            About             2025 Key                                                    Governance and Compliance                                 Green Operations to   Employee Development
                     About This                                                                   Sustainability                                                        Product System for Value
                                        from the          Hapharm          Performance in                               Special Topic    to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix                 2025 Sustainability Report
                      Report                                                                      Management                                                                    Creation
                                        Chairman           Group            Sustainability                                                      Stable Growth                                         Management             Shared Future
                                                                                                                                         Talent Development System
Talent Cultivation and Development
To achieve "standardization, process-orientation, institutionalization, informatization, digital intelligence, and assessment-based      The Company has constructed a talent development system centered around the three dimensions of "schools, instructors, and
management," the Company is comprehensively promoting the optimization and upgrading of its human resources system. This                 courses." It has re?ned the course matrix for all job categories and levels, focusing on core areas that directly impact business
includes implementing "full life-cycle" career management for employees and building a human resources management system that            operations, such as marketing, market development, e-commerce, and R&D. Key emphasis is placed on cultivating critical groups
aligns with market principles and matches the corporate culture. The Company focuses on building an incentive-oriented compensa-         including management trainees, reserve cadres, and high-potential employees. The Company fosters an organizational
tion and performance system and a capability-oriented talent development system. It strengthens the development of its cadre team        atmosphere combining "learning, practicing, testing, and competing," forging practical skills through project immersion and job
and talent echelon, adhering to the principle of "promoting the capable and demoting the mediocre." The Company increases invest-        rotation, ensuring that talent growth resonates with business development.
ment in talent cultivation, empowering management trainees and young cadres to grow through practical experience, thereby stimu-
lating organizational vitality and providing talent assurance for the implementation of the Company's strategy and high-quality devel-   The Company possesses a comprehensive position management and talent development system, providing clear and well-de?ned
opment.                                                                                                                                  career advancement channels for all job sequences, including R&D, production, marketing communication, and functional roles.
                                                                                                                                         In terms of talent development, the Company has assembled a professional faculty composed of department leaders and business
                                                                                                                                         backbones, built a customized curriculum system, and adopted diverse learning formats such as sharing sessions, attendance at
System and Framework Setup                                                                                                               important meetings, work reports, and study tours. For management personnel, echelon development is strengthened through job
                                                                                                                                         rotation, work reviews, and case studies. For grassroots personnel, the "master-apprentice" mentorship mechanism is continuous-
                                                                                                                                         ly promoted. Concurrently, a dynamic talent reserve pool has been established to provide solid support for both talent growth and
                                                                                                                                         corporate development. In 2025, the Company was recognized as a Harbin Municipal High-Skilled Talent Training Base and
                                                                                                                                         received the "AI Application Pioneer Award" from Beijing Beisen Cloud Computing Co., Ltd.
The Company has formulated the Position System Management Measures to standardize position information and job responsibili-
ties, laying a foundation for talent development. It has also formulated the Talent Development Management Measures, which,
based on knowledge, skills, and experience requirements for positions, constructs diverse development paths that vertically cover
management, professional, and operational tracks and horizontally support cross-track transfers. The R&D System Professional
Track Quali?cation Rating Scheme (Trial) has been formulated to detail professional promotion standards for R&D personnel,                          Case            Digitalization empowering internal learning and capability enhancement
opening up a seven-level professional development channel from assistant researcher to chief scientist, providing clear guidance
for R&D talent growth. At the same time, the Company has formulated and implemented the R&D Project Incentive Scheme (Trial),
centered on full life-cycle management of R&D projects, scienti?cally setting key milestone nodes and assessment indicators to                    In April 2025, the Company introduced an intelligent learning
continuously stimulate the innovative vitality of the R&D team.                                                                                   platform software to host internal and external learning
                                                                                                                                                  resources and shorten course production cycles using
                                                                                                                                                  AI-assisted course creation. Leveraging AI course creation
The Company has established and improved a talent development system, clarifying career development paths and promotion
                                                                                                                                                  features, the Company developed a total of 206 AI courses
rules through multiple policies. It also implements job value assessments, comprehensively evaluating job value based on seven
                                                                                                                                                  during the reporting period, saving approximately 500 hours
factors: span of control, scope of responsibilities, organizational impact, environmental conditions, problem-solving capabilities,
                                                                                                                                                  in course recording and post-production time, effectively
quali?cations, and communication requirements. In 2025, the Company further optimized its job mapping, scienti?cally differenti-
                                                                                                                                                  enhancing the ef?ciency of training resource development.
ated relative differences in job values, and re?ned the position management system. The Company formulated the Performance
                                                                                                                                                  Based on business scenarios, Renmintongtai applied AI-pow-
Management Measures to implement closed-loop performance management, adhering to the principle of "comprehensive horizon-
                                                                                                                                                  ered practice partner features to conduct sales staff training,
tal coverage and thorough vertical implementation." This ensures that all employees sign performance contracts and strengthens
                                                                                                                                                  focusing on strengthening pre-sales recommendations and
the application of performance results. Assessment outcomes are linked to performance bonuses, merit-based salary adjust-
                                                                                                                                                  drug follow-up capabilities. This not only improved training                           AI Application Pioneer Award
ments, cadre reappointment, competitive promotion, reserve talent selection, and targeted training, thereby motivating employees
                                                                                                                                                  ef?ciency but also facilitated the conversion of training
to achieve high performance. The Company implements the Cadre Appointment Management Measures, following the principle of
                                                                                                                                                  outcomes into actual business performance.
integrity and ability, and selects cadres through a combination of open competition and organizational appointment. Additionally,
the Company enforces a "one-year appointment" system for management personnel. Through comprehensive evaluation of perfor-
mance assessments, competency appraisals, work reports, and daily rewards and punishments, the Company determines eligibili-
                                                                                                                                                  Adhering to the talent attraction philosophy of "gathering
ty for cadre reappointment, continuously building a high-quality and professional management team.
                                                                                                                                                  people with brand, retaining them with ecosystem, motivat-
                                                                                                                                                  ing them with value, warming them with policy, and nurtur-
                                                                                                                                                  ing their growth," the Company expanded its employer
                                                                                                                                                  brand in?uence through 12 campus presentations, 23
                                                                                                                                                  dual-selection fairs, and university-enterprise collabora-
                                                                                                                                                  tions. It established a "Talent Subsidy" to enhance talent
                                                                                                                                                  attraction and implemented the "Harbin Talents New Policy
                                                                                                                                                  policies, the Company empowers the localized development                       University Job Fair      and Economics Job Fair
                                                                                                                                                  of talent, achieving win-win growth for talent, enterprise,
                                                                                                                                                  and city.
                                        Message             About           2025 Key                                                   Governance and Compliance                                      Green Operations to      Employee Development
                  About This                                                                        Sustainability                                                     Product System for Value
                                        from the           Hapharm        Performance in                               Special Topic   to Solidify a Foundation for                                   Advance Low-Carbon        to Build a Safe and   Appendix            2025 Sustainability Report
                   Report                                                                           Management                                                                 Creation
                                        Chairman            Group          Sustainability                                                     Stable Growth                                              Management                Shared Future
      Case          “Voyager Training Camp" program for reserve cadres                                                                            Case            University-enterprise collaboration: Advancing the joint cultivation mechanism for TCM talent
     To support the Company's strategy and talent needs and strengthen the reserve cadre echelon, the Company                                   The Company continuously improves its diversi?ed talent development system to meet the needs of the traditional
     launched the ?rst "Voyager Training Camp" for reserve cadres from March to October 2025, in accordance with                                Chinese medicine (TCM) industry. During the reporting period, Shiyitang Chinese Medicine signed a joint cultiva-
     the Reserve Cadre Selection and Development Plan. The program was held from March to October 2025 at                                       tion agreement with the School of Pharmacy, Heilongjiang University of Chinese Medicine and co-established a
     Heilongjiang University and the Headquarters Multi-function Hall. Training content covered diverse courses                                 joint cultivation base, promoting the implementation of a university-enterprise collaborative education mechanism.
     including leadership enhancement, management innovation, marketing, and ?nance. Teaching methods included                                  By co-building practical training platforms, involving corporate mentors in teaching, and organizing students to
     classroom interaction, case studies, and project presentations to systematically improve the comprehensive                                 participate in actual R&D and production projects, the two parties improved the alignment between talent cultiva-
     abilities of reserve cadres. A total of 76 trainees participated in this session; currently, 13 have been successfully                     tion and industry needs, enhancing students' practical skills and professional identity. Simultaneously, leveraging
     promoted, representing a promotion rate of 17%, securing a pool of high-quality management talent for the                                  the resource advantages of both the university and the enterprise in research and industry, they engaged in
     Company's development.                                                                                                                     exchange and cooperation in areas such as TCM R&D and the development of "Cold-Region Longjiang Medicines"
                                                                                                                                                resources. This explores a talent development path connecting teaching, practice, and scienti?c research, provid-
                                                                                                                                                ing stable talent support for the Company's sustainable development and the high-quality development of the TCM
                                                                                                                                                industry.
                   Leadership enhancement and management                  Financial management training course
                           innovation training course
      Case          "Chunlei Training Camp" for the 2025 Cohort of Management Trainees
                                                                                                                                                                                             Joint cultivation by Shiyitang Chinese Medicine and
                                                                                                                                                                                                 Heilongjiang University of Chinese Medicine
     In July 2025, the Company launched the "Chunlei Training Camp" for the 2025 cohort of management trainees.
     Themed "Hapharm Group's New Stars: Chasing Dreams Forward, Daring to Compete and Win," the program provid-
     ed 115 management trainees with a 10-day immersive intensive training. The training featured systematic courses
                                                                                                                                                   Key performance
     including team-building exercises, corporate culture, strategic branding, marketing planning, and professional
     ethics. Through diverse teaching formats such as centralized instruction, site visits and study tours, senior execu-
     tive symposiums, and project discussions and presentations, the program comprehensively empowered the
     growth of management trainees. It ef?ciently bridged the "last mile" from campus to the workplace, helping new                                                    Indicator name                                           Unit                       2025 data
     employees quickly integrate into the enterprise and become competent in their roles.
                                                                                                                                                                      Total training hours                                      Hours                       248,712.2
                                                                                                                                                            Average training hours per person                                   Hours                            24.77
                                                                                                                                                      Total number of training sessions for the year                            Times                            1,968
                                                                                                                                                          Total investment in employee training                         Ten thousand yuan                        295.71
                                                                                                                                                        Number of employee training participants                              Persons                            9,869
                                                                                                                                                             Employee training coverage rate                                      %                               98
                  Systematic curriculum training session                           Team-building exercises
                                                                                                                                                       Percentage of employees receiving regular
                                                                                                                                                      performance and career development reviews                                  %                               100
                                                                                                             Message                                            About                                   2025 Key                                                                                                                                     Governance and Compliance                                     Green Operations to   Employee Development
                                                           About This                                                                                                                                                                                          Sustainability                                                                                                         Product System for Value
                                                                                                             from the                                          Hapharm                                Performance in                                                                                            Special Topic                        to Solidify a Foundation for                                  Advance Low-Carbon     to Build a Safe and   Appendix         2025 Sustainability Report
                                                            Report                                                                                                                                                                                             Management                                                                                                                     Creation
                                                                                                             Chairman                                           Group                                  Sustainability                                                                                                                                       Stable Growth                                             Management             Shared Future
                                                                                                                                                                                                                                                                                                                                                     In recent years, the honors and awards received by Hapharm Group and its subsidiaries are as follows:
Occupational Health and Safety
 The Company has constructed a comprehensive safety management system. A Work Safety Committee is established as the
 highest authority for safety management, responsible for decision-making on major work safety matters, providing business
 support, and formulating overall safety management policies. A dedicated safety management department, the EHS and Engineer-
 ing Equipment Department, is responsible for setting safety assessment goals and indicators, establishing and operating the                                                                                                                                                                                                                                                        Hayao General Factory                                                Sanchine
 safety management system, conducting performance assessments, and investigating and handling major safety accidents. All
 subordinate industrial, R&D, and commercial units have established safety management departments responsible for decompos-                                                                                                                                                                                                                                                     In 2024, it was awarded the                                    In 2023, it was awarded the
 ing and implementing safety management goals and indicators, building and ensuring compliant operation of systems, pursuing                                                                                                                                                                                                                                                   title of Advanced Organization                                  title of Winning Unit in the
 continuous improvement, providing business training, fostering a safety culture, and investigating and handling safety accidents                                                                                                                                                                                                                                              Unit in the Harbin Ankang Cup                                   2021-2022        Heilongjiang
 within their respective units.                                                                                                                                                                                                                                                                                                                                                Competition,          and         the                           Province Ankang Cup
                                                                                                                                                                                                                                                                                                                                                                               recycling group of Workshop                                     in 2024, it was awarded the
                                                                                                                                                                                                                                                                                                                                                                               Excellent Team in the Ankang                                    2022-2023 Harbin "Ankang
                                                                                                                                                                                                                                                                                                                                                                               Cup.                                                            Cup" Competition.
                                                                                                                                                               President
                                                                                                                                                                                                       EHS and Engineering Equipment Department
                                                                                                                                                                                                                                                                                                                                                                                Shiyitang Chinese Medicine                                           Sanjing Mingshui
                                                              Hayao General Factory
                                                                                      Hayao Sanjing
                                                                                                      Hayao No.6 Factory
                                                                                                                                               Hapharm Group
                                                                                                                                                                                                                                           Marketing Company
                                                                                                                                                                                                                                                                Renmintongtai
                                                                                                                                                                                                                                                                                Health Technology
               Co., Ltd.
               Beijing Biotechnology
                                                                                                                                                                                                                                                                                                    GNC China
                                                                                                                           Medicine
                                                                                                                           Shiyitang Chinese
                                                                                                                                                                  Sanjing Mingshui
                                                                                                                                                                                     Sanjing Qianhe
                                                                                                                                                                                                       Sanjing Children
                                                                                                                                                                                                                          Sanjing Daqing
                                                                                                                                                                                                                                                                                                                                    Shenglin Asset
                                       Technology Center
headquarters
Company
                                                                                                                                                                                                                                                                                                                  Art and Culture
                                                                                                                                                                                                                                                                                                                                                                              In 2024, it won the "First Prize in                            In 2024, it was awarded the title
                                                                                                                                                                                                                                                                                                                                                                              the Team Competition of Mini                                   of "2024 Suihua City Occupa-
                                                                                                                                                                                                                                                                                                                                                                              Fire Stations for Key Fire Safety                              tional Health Enterprise."
                                                                                                                                                                                                                                                                                                                                                                              Units in Daoli District."
                                                                                                                 Organizational structure chart of the safety management
                                                                                                                                system of Hapharm Group
 The Company has formulated systems such as the Safety Management
 System Plan, Occupational Health Management Measures, and Procedures
 for Reporting, Investigating, and Handling of Work Safety Accidents and
 Emergency Rescue Plans for Safety Accidents and Sudden Incidents to
 strengthen work safety and occupational health management, prevent and
 reduce production safety accidents, and prevent occupational disease
 hazards, promoting its own sustainable and healthy development. As of the
 end of the reporting period, the Company's subsidiary, Sanjing Mingshui,
 obtained certi?cation under the ISO 45001 Occupational Health and Safety
 Management System.
                                                                                                                                                                                                                                     Sanjing Mingshui Occupational Health and Safety
                                                                                                                                                                                                                                       Management System Certi?cation Certi?cate
                                    Message        About        2025 Key                                            Governance and Compliance                                 Green Operations to   Employee Development
            About This                                                             Sustainability                                                  Product System for Value
                                    from the      Hapharm     Performance in                        Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and    Appendix                2025 Sustainability Report
             Report                                                                Management                                                              Creation
                                    Chairman       Group       Sustainability                                              Stable Growth                                         Management             Shared Future
                                                                                                                    The Company adheres to the safety management principle of "prevention ?rst, continuous improvement, zero accidents, and zero
                                                                                                                    pollution," promoting a comprehensive safety awareness enhancement plan and building a safety management system with
                                                                                                                    "leadership taking the lead and all employees participating." This plan integrates case analysis, experience sharing, ideological
                                                                                                                    education, and humanistic care, supported by a reward and penalty mechanism for violations. In 2025, the Company and its
                                                                                                                    subsidiaries implemented incentive measures such as the Ankang Cup competition, striving to create a safety culture of "full
                                                                                                                    participation and shared responsibility" through diverse cultural promotion.
           Medal for Advanced Organiza-                     Medal for Winning Team in the
           tion Unit in the Harbin Ankang                   Harbin Ankang Cup Competition
           Cup Competition awarded to                        awarded to Workshop 301 of
               Hayao General Factory                             Hayao General Factory                                          Case           Multi-pronged measures to enhance "dual-hazard" management and empower intrinsic safety
                                                                                                                             In July 2025, to thoroughly implement the Three-Year Action Plan for Tackling the Root Causes of Production
                                                                                                                             Safety (2024–2026) issued by the Of?ce of the State Council Work Safety Committee, Hayao General Factory
                                                                                                                             focused on the management of highly toxic, easily explosive, and other hazardous chemicals and dangerous
                                                                                                                             operations, comprehensively upgrading its "dual-hazard" control level. The Company organized over 40 safety
                                                                                                                             management personnel and key operational staff to conduct a special seminar on the new version of the Safety
                                                                                                                             Speci?cations of Special Work in Hazardous Chemicals Enterprises (GB 30871–2022). Through analysis of typical
                                                                                                                             cases and benchmarking against regulations, the seminar re?ned approval processes, strengthened on-site
                                                                                                                             supervision, and held in-depth discussions on issues such as "insuf?cient supervisor capabilities" and "dif?culties
                                                                                                                             in dynamic risk control," further solidifying the foundation for on-site management of special operations.
                                                                                                                             This special enhancement initiative aims to shift safety
                                                                                                                             management towards root cause governance and empower
           Medal for Winning Unit in the                     Medal for Winning Unit in the
                                                                                                                             enterprise intrinsic safety. By transforming institutional
           Heilongjiang Province Ankang                      Harbin Ankang Cup Competi-
                                                                                                                             norms into rigid constraints, it has effectively improved the
           Cup Competition awarded to                          tion awarded to Sanchine
                                                                                                                             scienti?c level of "dual-hazard" control. This is not only an
                         Sanchine
                                                                                                                             active response to the national campaign for tackling root
                                                                                                                             causes of work safety but also lays a solid safety foundation
                                                                                                                             for the Company's high-quality development.
                                                                                                                                                                                                            Safety-related laws and regulations training
     Medal for First Prize in the Team Competi-             Certi?cate for 2024 Suihua City
       tion of Mini Fire Stations for Key Fire              Occupational Health Enterprise
      Safety Units in Daoli District awarded to              awarded to Sanjing Mingshui
            Shiyitang Chinese Medicine
                                    Message             About                2025 Key                                            Governance and Compliance                                  Green Operations to   Employee Development
                 About This                                                                  Sustainability                                                      Product System for Value
                                    from the           Hapharm             Performance in                        Special Topic   to Solidify a Foundation for                               Advance Low-Carbon     to Build a Safe and   Appendix          2025 Sustainability Report
                  Report                                                                     Management                                                                  Creation
                                    Chairman            Group               Sustainability                                              Stable Growth                                          Management             Shared Future
      Case         Sanchine building an intelligent safety management system                                                     The Company has established a regular risk identi?cation mechanism, conducting annual risk identi?cation work and promptly
                                                                                                                                 initiating identi?cation and response actions in the event of signi?cant changes. For identi?ed risks, the Company implements
     As a comprehensive pharmaceutical enterprise, Sanchine is characterized by numerous buildings on its premises               classi?ed control: safety risks are categorized into four levels—major, signi?cant, general, and low; environmental and occupation-
     and a wide scope of control. Addressing pain points such as cumbersome approvals and blind spots in patrols                 al health risks are divided into two levels—major and general. Since 2022, the Company and its subsidiaries have progressively
     under traditional safety management, Sanchine has innovatively built an intelligent safety management system. It            carried out risk classi?cation and control work, completing the comprehensive identi?cation and assessment of major risks. Corre-
     developed a big data approval platform that integrates multiple databases to achieve automatic quali?cation                 sponding control measures and emergency plans have been formulated for different risk levels, building a dynamically managed
     veri?cation and generate assessment reports within three minutes. It upgraded video surveillance to provide                 risk prevention and control network.
     "platform + hardware," the ef?ciency of safety operation approvals increased by 60%, hazard investigation cover-            In terms of occupational health and safety management, the Company set a management goal of zero work safety accidents and
     age reached 100%, and emergency response speed improved by 50%. This drove the transformation of safety                     a continuous decline in safety incidents. During the reporting period, the Company strictly adhered to the red lines of safety and
     management from "passive response" to "proactive prevention," solidifying the safety line of defense in the                 occupational health management, achieving zero work safety accidents, ?re incidents, and traf?c accidents. All required occupa-
     pharmaceutical sector.                                                                                                      tional health examinations were conducted, all workplaces with occupational hazard factors were fully monitored, and no new
                                                                                                                                 cases of occupational disease were reported, providing a solid safety guarantee for production and operations.
                                                                                                                                             Key performance
                                                                                                                                                                Indicator name                                     Unit                       2025 data
                                                                                                                                              Total duration of occupational health and work                      Hours                         85,336
                                                                                                                                                       safety training for employees
                                                                                                                                              Total duration of occupational health and work                                                   8,226.5
                                                                                                                                                                                                                  Hours
                                                                                                                                               safety training for suppliers and contractors
                                                                                                                                            Number of safety drills (?re, toxic gas leaks, etc.)             Number of times                        121
                                                                                                                                               Investment in occupational health and safety
                                                                                                                                                               management                                  Ten thousand yuan                    753.10
                                           Real-time monitoring by the digital system
                                                                                                                                              Investment amount for employee work-related
                                                                                                                                                           injury insurance                                Ten thousand yuan                    573.46
                                                                                                                                               Investment amount for employee work safety
                                                                                                                                                           liability insurance                             Ten thousand yuan                        6.28
                                                                                                                                            Number of work-related injuries (minor and above)                     Persons                            0
                                                                                                                                                      Number of work-related fatalities                           Persons                            0
                                                                                                                                               Number of workdays lost due to work-related                         Days                              0
                                                                                                                                                               injuries
                                                                                                                                                    Occupational disease incidence rate                             %                                0
                                                    Aerial patrols by drones
                                        Message              About                2025 Key                                                  Governance and Compliance                                       Green Operations to   Employee Development
                    About This                                                                       Sustainability                                                           Product System for Value
                                        from the            Hapharm             Performance in                              Special Topic   to Solidify a Foundation for                                    Advance Low-Carbon     to Build a Safe and     Appendix         2025 Sustainability Report
                     Report                                                                          Management                                                                       Creation
                                        Chairman             Group               Sustainability                                                    Stable Growth                                               Management             Shared Future
Rural Revitalization Practices                                                                                                                          Case           Party building as a pen to paint a new picture of revitalization for Sixin Village
                                                                                                                                                     The Company has provided targeted assistance to Sixin Village in Yilan County, Harbin, Heilongjiang Province for
To consolidate and expand the achievements of poverty alleviation and effectively link them with rural revitalization, the Company
                                                                                                                                                     nine consecutive years. Through multi-dimensional initiatives including industrial support, infrastructure improve-
actively responded to the national rural revitalization strategy deployment. Relying on the Heilongjiang Hapharm Foundation, it
                                                                                                                                                     ment, healthcare assistance and Party-building collaboration, the Company has helped the village achieve poverty
planned and implemented the "Hapharm Foundation Rural Guardian Program." Adhering to the principle of "adapting measures to
                                                                                                                                                     alleviation and advance rural revitalization. Adopting a systematic and sustainable assistance model, the Company
local conditions and implementing targeted policies," the project focuses on health security and implements targeted assistance
                                                                                                                                                     has aligned its efforts with local needs, with Party-building as the guiding approach and industrial empowerment
measures, empowering rural revitalization through corporate responsibility and effectively safeguarding the health and well-being
                                                                                                                                                     as the key driver, leading targeted support initiatives to ensure effective implementation.
of the people. During the reporting period, the Company donated a total of RMB 60,000 worth of common medicines to rural areas.
These supplies were distributed through grassroots health institutions to precisely meet the daily medication and common disease
treatment needs of the residents. The project bene?ted 16 villages and 4,755 people in Heilongjiang Province.                                        The     Company’s         Party    committee         has
                                                                                                                                                     strengthened          rural   assistance        through
                                                                                                                                                     Party-building          practices,        establishing
                                                                                                                                                     Party-building        walls    and       corridors    to
          Case         Warming old revolutionary base areas and safeguarding health
                                                                                                                                                     promote      Party      theories     and       historical
                                                                                                                                                     stories, and supporting Sixin Village in being
       From October to November 2025, the Company, through the Hapharm Foundation, visited seven old revolutionary
                                                                                                                                                     recognized as a provincial-level demonstra-
       base area villages in Hulan District, Bin County, and other areas to conduct health outreach activities, contributing
                                                                                                                                                     tion village for Party-building. The Company
       to rural revitalization with practical actions. Based on preliminary surveys of villagers' health needs, a total of 9,000
                                                                                                                                                     has also supported the development of the
       boxes of common medicines for colds, gastrointestinal issues, and in?ammation were donated on-site. In collabo-
                                                                                                                                                     village’s fungus greenhouse industry to
       ration with township health centers and village doctors, one-on-one medication guidance was provided to villagers,
                                                                                                                                                     increase income for the collective economy
       and knowledge on safe medication use was disseminated. Through a model of "material donation + professional                                                                                                                         Party building corrido
                                                                                                                                                     and    households        lifted    out    of    poverty,
       services," the activity effectively addressed the issues of "dif?culty in purchasing and using medicine" for villagers
                                                                                                                                                     organized a resident work team to assist in
       in old revolutionary base areas. It received widespread recognition from local village committees and villagers,
                                                                                                                                                     improving the village environment, and used
       injecting solid health momentum into rural revitalization.
                                                                                                                                                     special funds to procure rice, ?our and
                                                                                                                                                     cooking oil to provide support to households
                                                                                                                                                     lifted out of poverty during the Spring
                                                                                                                                                     Festival. During the reporting period, the
                                                                                                                                                     Company invested a total of RMB 310,200 in
                                                                                                                                                     assistance, bene?ting 630 people. Prior to
                                                                                                                                                     the Spring Festival, supplies such as rice,
                                                                                                                                                     ?our and cooking oil were distributed to
                                                                                                                                                     households lifted out of poverty, while
                                                                                                                                                     resident team members also assisted in                                        Village-based work team assisting with
                                                                                                                                                     cleaning the village environment, contribut-                                            sanitation cleanup
                                                                                                                                                     ing to rural development and improved
                                                                                                                                                     livelihoods.
                                                                                                                                                        During the reporting period, the Company
                                                                                                                                                     Invested RMB           ???,??? in rural revitalization,Bene?tted?,??? people
                                                    On-site distribution of medicines
                                         Message            About              2025 Key                                                     Governance and Compliance                                  Green Operations to     Employee Development
                     About This                                                                      Sustainability                                                        Product System for Value
                                         from the          Hapharm           Performance in                                 Special Topic   to Solidify a Foundation for                               Advance Low-Carbon       to Build a Safe and   Appendix             2025 Sustainability Report
                      Report                                                                         Management                                                                    Creation
                                         Chairman           Group             Sustainability                                                       Stable Growth                                          Management               Shared Future
                                                                                                                                            The Company has always practiced the volunteer service spirit of "dedication, friendship, mutual assistance, and progress." It
Public Welfare and Social Action                                                                                                            innovatively created the distinctive volunteer service project "Hapharm Foundation, Rescue is at Hand," focusing on two core areas:
                                                                                                                                            voluntary blood donation and cardiopulmonary resuscitation (CPR) ?rst aid skills training, regularly carrying out volunteer service
                                                                                                                                            activities. In 2025, the Company actively organized voluntary blood donation events, with 723 volunteers from 15 units participating
                                                                                                                                            to spread warmth. Concurrently, two sessions of cardiopulmonary resuscitation (CPR+AED) ?rst aid skills training were conducted,
For many years, the Company has adhered to the charitable purpose of "developing public welfare and charity and promoting
                                                                                                                                            with 90 volunteers enhancing their emergency response capabilities.
social civilization and progress." It has deeply integrated public welfare into its corporate sustainability strategy and continuously
invested resources to support the high-quality development of public welfare undertakings. The Company established a profes-
sional and standardized public welfare management system and a full-process support mechanism to ensure that public welfare                             Case           Volunteering to warm the Asian Winter Games: Hapharm Group in action
resources are precisely matched, ef?ciently implemented, and practically effective. Over the past three years, the Company has
donated a total of RMB 39.394 million in funds and materials, bene?ting 460,400 people. Focusing on key social needs, the
Company concentrated on critical areas such as caring for the elderly and children, disaster emergency relief, and volunteer
                                                                                                                                                    During the preparation and hosting of the 9th Asian Winter Games in Harbin, the Company actively responded to
services. It meticulously created branded public welfare projects including "Hope Guards Health, Hapharm Group Grows with Me,"
                                                                                                                                                    the call and organized 41 employee volunteers to participate in city-side volunteer services. Volunteers stationed
"Happiness 1+1," "Warming the Sunset Years, Guarding the Silver-Haired," and "Hapharm Foundation, Rescue is at Hand." This
                                                                                                                                                    at Harbin Railway Station provided considerate services such as civility guidance and inquiry resolution for passing
formed a regular, diversi?ed, and sustainable pattern of public welfare practice, demonstrating corporate social responsibility
                                                                                                                                                    tourists. Along the torch relay route, they cheered for torchbearers with full enthusiasm, conveying the warmth of
through practical actions.
                                                                                                                                                    the Asian Winter Games and demonstrating the demeanor of the host through practical actions. This volunteer
                                                                                                                                                    service received wide social recognition. The Social Work Department of the Harbin Municipal Committee of the
         During the reporting period, the Company                                                                                                   Communist Party of China awarded certi?cates for
                                                                                                                                                    city-side volunteer service at the Asian Winter
                                                                                                                                                    Games to the 41 volunteers, fully af?rming their
      Invested RMB ???,???                 in the social welfare      Helped   ?,???           people through the public welfare                    hard work and sense of responsibility. At the
                                                                      initiatives                                                                   summary and commendation conference of the
      Organized   ???        employees in volunteer activities        Had an average service duration of    ?.??        hours per                   Asian Winter Games, the Harbin Pharmaceutical
                                                                                                                                                    Group Holding Co., Ltd. Asian Winter Games Volun-
                                                                      person for employee volunteer activities
                                                                                                                                                    teer Service Team was awarded the provincial-level
                                                                                                                                                    "Advanced Collective" title, and Hapharm Group.
                                                                                                                                                    was awarded the municipal-level "Advanced Collec-
Public welfare donations and volunteer services                                                                                                     tive" title. These dual honors highlighted the enter-
                                                                                                                                                    prises' social responsibility and public welfare
The Company carries out external donations and assistance actions mainly through its Hapharm Foundation and continuously                            spirit, and represented the enterprises' contribu-                   9th Harbin Asian Winter Games Torchbearer – Employee
expands forms of public welfare participation by organizing employee volunteer services.                                                            tion to the successful hosting of the Asian Winter                                  of Sanjing Pharmaceutical
                                                                                                                                                    Games.
         Case         Hapharm Foundation creating a journey of growth through ice and snow study tours
       In January 2025, the Company planned and imple-
       mented the "Budding Growth: Winter Journey with Ice
       and Snow" public welfare study tour activity, inviting
       children from Daliangshan in Sichuan, Yinchuan in
       Ningxia, and Putian in Fujian to visit Harbin. The
       children were immersed in the charm of ice and snow,
       experienced curling, visited art exhibitions, and more.
       This heartwarming initiative lit up childhood dreams
       and safeguarded the healthy growth of children. In
       May, Company volunteers made a special return visit to
       Ningxia to ful?ll the promises of the "Dream Archives."
       Through measures such as holding popular science
       lectures on children's bone nutrition and donating
       sports equipment, they continued to convey care. This
       activity not only broadened the horizons of rural                                                                                                                                     Volunteer service activity at Harbin Railway Station
       children but also vividly interpreted the public welfare
       concept of "Health Guards Dreams," demonstrating
       the Company's sense of social responsibility.
                                                                            "Budding Growth: Winter Journey with Ice and Snow"
                                                                                   public welfare study tour activity site
                                                     Message               About                  2025 Key                                                  Governance and Compliance                                 Green Operations to   Employee Development
                             About This                                                                                    Sustainability                                                  Product System for Value
                                                     from the             Hapharm               Performance in                              Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix        2025 Sustainability Report
                              Report                                                                                       Management                                                              Creation
                                                     Chairman              Group                 Sustainability                                                    Stable Growth                                         Management             Shared Future
Social services and public value
                                                                                                                                                                        Case           Professional nutrition empowering event services and promoting a healthy lifestyle for all persons
Leveraging its advantages in the pharmaceutical and healthcare industry, the Company carried out diverse social service practic-
es focusing on public health services, care for special groups, and urban public services. While improving service accessibility,                                   In May 2025, GNC China participated in the 2025 West Lake Half Marathon in Hangzhou, providing participants with
it actively created social value.                                                                                                                                   systematic nutritional support before, during and after the race. The Company provided joint health supplements
                                                                                                                                                                    prior to the race, organized support teams to offer on-site supplies during the race, and worked with medical and
                                                                                                                                                                    rehabilitation teams after the race to provide stretching and recovery guidance. An on-site experience area was
                 Case          Travel dialysis: Worry-free love
                                                                                                                                                                    also set up to offer nutrition consultation and health services. Through an integrated “product + service + experi-
                                                                                                                                                                    ence” support model, the Company promoted scienti?c sports nutrition concepts, enhanced public awareness of
            In December 2025, Heilongjiang Sanjing Nephropathy Hospital                                                                                             healthy dietary supplementation, and strengthened its professional image in the sports health sector, contributing
            centered on patients’ needs, integrated health science popular-                                                                                         to a culture of scienti?c ?tness and active lifestyles.
            ization and service innovation, and held a themed event at
            Parkson Shopping Center on Central Street. The hospital
            assembled a professional medical team of 10 members, with
            on-site consultation desks, case exhibition areas and interac-
            tive experience zones. It systematically explained the proce-
            dures, precautions of travel dialysis as well as off-site dialysis
            appointment       support     services,     addressing      questions     and
            concerns of kidney disease patients.The event innovatively
            integrated traditional Chinese medicine expertise with the
            distinctive travel dialysis service, enabling patients to under-
            stand the feasibility of receiving dialysis while traveling. It
            effectively removed travel restrictions for kidney patients and                                                                                                                                             GNC China event support
            delivered the humanistic medical philosophy of people-oriented
                                                                                                                       Event Site
            care. Meanwhile, leveraging the large foot traf?c of the venue,
            the event further raised public awareness of specialized medical
                                                                                                                                                            The Company actively ful?lled its social responsibilities, focusing on the integrated development of cultural communication and
            services, bringing high-quality.
                                                                                                                                                            public welfare. It leveraged its professional resources to carry out diverse cultural activities, promoting the combination of cultural
                                                                                                                                                            heritage protection and public education, and continuously enhancing social and cultural awareness and participation.
                                                                                                                                                                       Case            Special exhibition of repatriated cultural relics to promote cultural communication
                 Case          Caring for new employment groups with heartwarming services to safeguard health
                                                                                                                                                                    In 2025, the Company, in collaboration with relevant units, held the "National Treasures Gather in the Ice City—
            To genuinely care for the physical and mental health of new employment groups such as couriers and ride-hailing                                         Special Exhibition of Repatriated Cultural Relics" in Harbin, with multi-party teams participating in the curation and
            drivers, Renmintongtai actively engaged in safeguarding their health. It took the initiative to integrate its pharma-                                   implementation. Centered on repatriated cultural relics, the exhibition presented their historical value and dissemi-
            ceutical resources to build a comprehensive health protection system covering medication discounts, health                                              nated knowledge on their protection through systematic displays and on-site explanations. The event effectively
            services, and green medical channels, putting into practice the concept of government-enterprise collaboration for                                      enhanced public awareness and consciousness of cultural heritage protection, increased social participation, and
                                                                                                                                                                    promoted the integration of cultural resources with the city's cultural tourism. This re?ected the enterprise's
            public bene?t. Renmintongtai selected 500 common
                                                                                                                                                                    responsible values in cultural communication and public welfare practices.
            drugs to offer exclusive discounts, effectively reduc-
            ing the medication burden on new employment
            groups. It established "Heartwarming Stations" in its
            pharmacies, providing a range of services including
            emergency medicine, health monitoring, and conve-
            nient rest areas. From a cup of plum juice in the
            summer to a cup of warming tea in the winter, these
            small acts of kindness warmed every frontline worker
            in   new     employment        groups.     Through      practical
            actions, it conveyed warmth, helping to enhance the
            sense of gain and happiness for these groups and
            making the city warmer.                                                                   Launch ceremony of the event                                                         Special Exhibition site                                Bronze Animal Heads Exhibition
    Heilongjiang Sanjing Nephropathy Hospital is a non-pro?t Grade III specialized hospital af?liated with Rentongtai (600829.SH),
a subsidiary under the Company’s holding.
                                  Message                About      2025 Key                                                                        Governance and Compliance                                 Green Operations to   Employee Development
             About This                                                                     Sustainability                                                                         Product System for Value
                                  from the              Hapharm   Performance in                                   Special Topic                    to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix   2025 Sustainability Report
              Report                                                                        Management                                                                                     Creation
                                  Chairman               Group     Sustainability                                                                          Stable Growth                                         Management             Shared Future
         Honors and awards of Hapharm Group
      HARBIN PHARMACEUTICAL GROUP CO., LTD. was awarded                                HARBIN PHARMACEUTICAL GROUP CO., LTD.
                          the First "Longjiang                                                          was awarded the
       Charity Award—Donor Enterprise Award" of the Province                        "2020–2021 National Blood Donation Promotion Award"
                    Heilongjiang Civil Administration                           National Health Commission of the People's Republic of China, Red
                            Information Net                                       Cross Society of China, Health Bureau of the Logistic Support
                                                                                    Department of China's Central Military Commission (CMC)
           HARBIN PHARMACEUTICAL GROUP CO., LTD.                                          Harbin Pharmaceutical Group Co., Ltd. was
        was awarded the "Heilongjiang Province Youth Public                             awarded the Municipal Advanced Collective for
            Welfare Activity Research and Practice Base"                                     the 9th Harbin Asian Winter Games
                Heilongjiang Provincial Committee of the                                   by the CPC Harbin Municipal Committee and
                 Communist Youth League, Heilongjiang                                         Harbin Municipal People’s Government
                     Youth Development Foundation
                                            Message               About              2025 Key                                                 Governance and Compliance                                 Green Operations to    Employee Development
                       About This                                                                           Sustainability                                                   Product System for Value
                                            from the             Hapharm           Performance in                             Special Topic   to Solidify a Foundation for                              Advance Low-Carbon      to Build a Safe and     Appendix             2025 Sustainability Report
                        Report                                                                              Management                                                               Creation
                                            Chairman              Group             Sustainability                                                   Stable Growth                                         Management              Shared Future
Key Performance Table
                                         Indicator                                                         Unit              2025 data                                                  Indicator                                                        Unit                 2025 data
 Governance Performance                                                                                                                       Environmental Performance
 Operating revenue                                                                                    RMB 100 million         ???.??          Number of participants in environmental management training                                             Person-times               ?,???
 Total assets                                                                                         RMB 100 million         ???.??          Number of participants in environmental protection publicity and public welfare activities                Persons                   ???
 Net assets attributable to shareholders of the listed company                                        RMB 100 million          ??.??          Number of emergency drills for environmental risk incidents conducted                                    Sessions                    ??
 Net pro?t attributable to shareholders of the listed company                                         RMB 100 million           ?.??          Number of participants in environmental emergency risk drills                                             Persons                  ?,???
 Basic earnings per share                                                                             Yuan per share            ?.??          Total greenhouse gas emissions                                                                  Tonnes of CO2 equivalent        ???,???.??
 Total tax payments                                                                                   RMB 100 million           ?.??          Photovoltaic power generation                                                                              MWh                    ?,???.??
 Percentage of independent directors                                                                        %                   ??.?          Proportion of clean energy consumption to total energy consumption                                           %                     ??.??
 Percentage of female directors                                                                             %                   ??.?          Total clean energy consumption (photovoltaic, natural gas)                                       Tonnes of standard coal         ??,???.??
 Number of Board of Directors meetings held                                                               Times                 ??            Direct energy consumption                                                                        Tonnes of standard coal         ??,???.??
 Director attendance rate                                                                                   %                   ???           Indirect energy consumption                                                                      Tonnes of standard coal         ??,???.??
 Number of director training sessions conducted                                                           Times                  ?            Total energy consumption                                                                         Tonnes of standard coal         ??,???.??
 Number of Shareholders' Meetings held                                                                    Times                  ?            Energy consumption intensity per million RMB in revenue                                      Tonnes/RMB 1 million in revenue        ?.??
 Total number of investor questions received                                                              Times                 ???           Total water consumption                                                                                   Tonnes                 ?,???,???
 Investor question response rate                                                                            %                  ??.??          Freshwater consumption                                                                                    Tonnes                 ?,???,???
 Integrity risk assessment coverage for the Company and its subsidiaries                                    %                   ???           Recycled water consumption                                                                                Tonnes                ??,???,???
 Employee signing rate for compliance commitment letters                                                    %                   ???           Water consumption intensity per million RMB in revenue                                       Tonnes/RMB 1 million in revenue       ???.??
 Signing rate of Integrity Commitment Letters for bidding suppliers                                         %                   ???           Total amount of wastewater discharge                                                                      Tonnes                 ?,???,???
 Number of compliance risks identi?ed during the year                                                     Items                 ???           Chemical oxygen demand (COD)                                                                              Tonnes                   ??.??
 Number of compliance risk response plans formulated                                                      Copies                ??            Ammonia nitrogen (NH3-N)                                                                                  Tonnes                    ?.??
 Number of compliance training sessions conducted                                                         Times                  ?            Total waste gas                                                                                         Cubic meter              ??,???.??
 Number of employees covered by compliance training                                                    Person-times            ?,???          Particulate matter (PM)                                                                                   Tonnes                    ?.??
 Number of anti-commercial bribery and anti-corruption training sessions conducted                        Times                 ??            Sulfur oxides (SOx)                                                                                       Tonnes                    ?.??
 Employees participating in anti-commercial bribery and anti-corruption training                       Person-times            ?,???          Nitrogen oxides (NOx)                                                                                     Tonnes                   ??.??
 Number of internal audit projects conducted                                                              Items                 ??            Volatile organic compounds (VOCs)                                                                         Tonnes                   ???.??
                                                                                                                                              Total hazardous waste                                                                                     Tonnes                   ???.??
                                                                                                                                              Total non-hazardous waste                                                                                 Tonnes                  ?,???.??
                                         Indicator                                                         Unit              2025 data
                                                                                                                                              Waste recycling rate                                                                                         %                     ??.??
 Environmental Performance
                                                                                                                                              Hazardous waste intensity                                                                    Tonnes/RMB 1 million in revenue        ?.??
 Total investment in environmental protection                                                        Ten thousand yuan        ?,???.??
                                                                                                                                              Non-hazardous waste intensity                                                                Tonnes/RMB 1 million in revenue        ?.??
 Total duration of environmental management training                                                      Hours                ?,???
                                             Message            About                 2025 Key                                                 Governance and Compliance                                   Green Operations to   Employee Development
                        About This                                                                           Sustainability                                                    Product System for Value
                                             from the          Hapharm              Performance in                             Special Topic   to Solidify a Foundation for                                Advance Low-Carbon     to Build a Safe and      Appendix         2025 Sustainability Report
                         Report                                                                              Management                                                                Creation
                                             Chairman           Group                Sustainability                                                   Stable Growth                                           Management             Shared Future
                                          Indicator                                                         Unit              2025 data                                                   Indicator                                                           Unit           2025 data
 Social Performance                                                                                                                            Social Performance
 Total R&D investment                                                                                 Ten thousand yuan       ??,???.??        Number of newly hired employees                                                                              Persons              ???
 Proportion of R&D investment to operating revenue                                                           %                  ?.??           Number of ethnic minority employees                                                                          Persons              ???
 Proportion of R&D investment to operating revenue of the industrial segment                                 %                  ?.??           Number of employees with disabilities                                                                        Persons              ???
 Proportion of R&D personnel                                                                                 %                  ??.??          Employee turnover rate                                                                                          %                   ?
 Total number of valid patents held                                                                         Items                ???           Employee bene?t coverage rate                                                                                   %                 ???
 Total number of invention patents applied for in the year                                                  Items                ??            Employee trade union coverage rate                                                                              %                 ???
 Total number of invention patents granted in the year                                                      Items                 ?            Total duration of employee training                                                                           Hours            ???,???.?
 Total number of valid trademarks held                                                                      Items                ???           Average training hours per person                                                                             Hours              ??.??
 Total amount of scienti?c and technological innovation awards granted                                Ten thousand yuan        ???.??          Total number of training sessions for the year                                                                Times              ?,???
 Number of projects recognized with scienti?c and technological innovation awards                           Pcs                  ???           Total investment in employee training                                                                    Ten thousand yuan       ???.??
 Number of major quality accidents throughout the year                                                     Times                  ?            Number of employee training participants                                                                     Persons             ?,???
 Number of non-conformance announcements                                                                    Items                 ?            Employee training coverage rate                                                                                 %                  ??
 Product quali?cation rate                                                                                   %                   ???           Percentage of employees receiving regular performance and career development reviews                            %                 ???
 Customer feedback handling rate                                                                             %                   ???           Total duration of occupational health and work safety training for employees                                  Hours              ??,???
 Number of responsible marketing audits conducted                                                          Times                 ??            Total duration of occupational health and work safety training for suppliers and contractors                  Hours             ?,???.?
 Total number of suppliers                                                                                 Counts               ?,???          Number of safety drills                                                                                   Number of times         ???
 Proportion of local suppliers                                                                               %                  ??.??          Investment in occupational health and safety management                                                  Ten thousand yuan       ???.??
 Local procurement ratio                                                                                     %                  ??.??          Investment amount for employee work-related injury insurance                                             Ten thousand yuan       ???.??
 Number of suppliers with document audits conducted                                                        Counts               ?,???          Investment amount for employee work safety liability insurance                                           Ten thousand yuan        ?.??
 Number of suppliers with on-site audits conducted                                                         Counts                ???           Number of work-related injuries (minor and above)                                                            Persons                ?
 Suppliers that underwent and passed environmental and social audits                                       Counts                ??            Number of work-related fatalities                                                                            Persons                ?
 Number of supplier training sessions conducted                                                            Times                 ???           Occupational disease incidence rate                                                                             %                   ?
 Total number of employees                                                                                Persons              ??,???          Total investment in rural revitalization                                                                 Ten thousand yuan       ??.??
 Number of female employees                                                                               Persons               ?,???          Number of people bene?ting from rural revitalization                                                         Persons             ?,???
 Number of male employees                                                                                 Persons               ?,???          Investment in social welfare                                                                             Ten thousand yuan         ??
 Number of employees aged 30 and below                                                                    Persons                ???           Number of people assisted through public welfare initiatives                                                 Persons             ?,???
 Number of employees aged 31 to 40                                                                        Persons               ?,???          Number of employee participations in volunteer activities                                                  Person-times           ???
 Number of employees aged 41 to 50                                                                        Persons               ?,???          Average service hours per person for employee volunteer activities                                            Hours               ?.??
 Number of employees aged 51 and above                                                                    Persons               ?,???          Number of participants covered by sustainable development training                                         Person-times            ??
                                              Message             About                2025 Key                                                               Governance and Compliance                                 Green Operations to   Employee Development
                       About This                                                                                Sustainability                                                              Product System for Value
                                              from the           Hapharm             Performance in                                           Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix      2025 Sustainability Report
                        Report                                                                                   Management                                                                          Creation
                                              Chairman            Group               Sustainability                                                                 Stable Growth                                         Management             Shared Future
Index of Indicators                                                                                                                                           Reader Feedback Form
                                                                                                                                                              Dear Readers,
                                                                 Guidelines No. 14 of Shanghai Stock                     Guidelines for Sustain-
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                       Contents                                   Listed Companies – Sustainability                       Chinese Enterprises                 Thank you for reading the 2025 Sustainability Report of HARBIN PHARMACEUTICAL GROUP CO., LTD. We highly value your
                                                                            Report (Trial)                                 (CASS-ESG 6.0)
                                                                                                                                                              valuable opinions and suggestions and sincerely invite you to evaluate this report. Every piece of your feedback will help us contin-
 About This Report                                                                    -                                                P?                     uously optimize the quality of our ESG information disclosure, improve our sustainability management system, better ful?ll our
                                                                                                                                                              social responsibilities as a pharmaceutical enterprise, and safeguard public health and well-being.
 Message from the Chairman                                                            -                                                P?
 About Hapharm Group                                                                  -                                                P?
 Sustainability management                                  Communications with stakeholders and due diligence                    G?.?,G?.?,G?.?
                                                                                                                                                              I. What is your identity:
 Special topic: Empowering with a digital and intelligent
 engine, building a foundation for high-quality                               Innovation-driven                                        S?.?
 development through technological innovation
                       Party building leadership and                                                                                                          □ Shareholder and investor □ Creditor □ Company employee □ Partner and industry association
                       responsibility implementation
 Governance and                                                                                                                                               □ Customer □ Supplier and contractor □ Media and public □ Government and regulatory agency
                       Construction of corporate
 compliance to                                                                                                                         G?.?
                       governance system
 solidify a                                                                                                                                                   □ Other __________
 foundation for        Internal control and compliance
                       management                                                                                                      G?.?
 stable growth
                       Culture of integrity and ethical         Anti-commercial bribery, anti-corruption, and
                       business practices                                anti-unfair competition                                    G?.?,G?.?                 II. Your overall evaluation of this report:
                       Technological r&d and
                                                                       Innovation-driven development                                   S?.?
                       innovation-driven development
                       Ethics of science and technolo-                                                                                                        What is your evaluation of the overall content of this report:
                                                                     Ethics of science and technology
                       gy
                       Industrial cooperation and                                                                                                             □ Excellent □ Good □ Average □ Poor □ Very poor
 Product system        exchange
 for value creation    Product quality and safety           Equal treatment to small and medium-sized enterpris-
                       management                              es; Safety and quality of products and services
                                                                                                                                    S?.?,S?.?
                                                                                                                                                              Do you think this report comprehensively and objectively re?ects the company's actual performance in the environmental, social,
                       Customer rights and interests
                                                               Data security and customer privacy protection                           S?.?
                       and service assurance                                                                                                                  and governance (ESG) ?elds in 2025?
                       Supply chain management and
                                                                            Supply chain security                                      S?.?
                       security                                                                                                                               □ Very adequate □ Relatively adequate □ Average □ Relatively inadequate □ Inadequate
                       Information security and privacy
                                                               Data security and customer privacy protection                           S?.?
                       protection
                       Medicine accessibility enhance-
                                                                                                                                                              Do you think the information disclosed in this report is clear, accurate, and complete:
                       ment
                       Environmental compliance
                                                                  Environmental compliance management
                                                                                                                                                              □ Very high □ High □ Average □ Low □ Very low
                                                                                                                                       E?.?
                       management
                       Climate change tackling                             Climate change tackling                                     E?.?
 Green operations                                                                                                                                             What do you think of the structural design and readability of this report:
                       Energy and resource manage-
 to advance                                                     Energy utilization, water resource utilization                      E?.?,E?.?
                       ment                                                                                                                                   □ Excellent □ Good □ Average □ Poor □ Very poor
 low-carbon
 management            Pollutant emissions                                   Pollutant discharge                                       E?.?
                       Waste management                            Waste management, circular economy                               E?.?,E?.?                 III. Your opinions and suggestions:
                       Ecosystem and biodiversity                  Ecosystem and biodiversity protection                               E?.?
                       conservation
                       Employee rights and well-being                                                                                  S?.?
                       Talent cultivation and develop-                           Employees                                             S?.?
 Employee              ment
 development to
 build a safe and      Occupational health and safety                                                                                  S?.?
 shared future
                       Rural revitalization practices                        Rural revitalization                                      S?.?
                       Public Welfare and Social Action                 Contributions to the society                                   S?.?
                                        Message            About             2025 Key                                                  Governance and Compliance                                 Green Operations to   Employee Development
                     About This                                                                   Sustainability                                                      Product System for Value
                                        from the          Hapharm          Performance in                              Special Topic   to Solidify a Foundation for                              Advance Low-Carbon     to Build a Safe and   Appendix            2025 Sustainability Report
                      Report                                                                      Management                                                                  Creation
                                        Chairman           Group            Sustainability                                                    Stable Growth                                         Management             Shared Future
Independent Assurance and Statement of Opinion                                                                                         4. Selected the relevant part of environmental, social and governance information in this Report, performed analytical assurance
                                                                                                                                       procedures for such information, con?rmed the overall performance situation, and evaluated and veri?ed whether the contents
                                                                                                                                       of the Report are complied with.
InFaith Consulting (hereinafter referred to as "InFaith"), as entrusted by Harbin Pharmaceutical Group Co., Ltd. (hereinafter          and its related AA1000 to con?rm the appropriateness of this Statement.
referred to as "Hapharm Group"), has conducted independent limited assurance of the environmental, social and governance               6. Sampled inspection on supporting evidence of data reliability and quality of selected speci?c performance information.
information and data disclosed in 2025 Sustainability Report of Hapharm Group (hereinafter referred to as "the Report"), and           7. Recalculated and veri?ed the selected speci?c performance information.
disclosed the assurance result and conclusion to readers of the Report in the form of independent assurance and statement of           8. Performed other procedures that we deemed necessary.
opinion.
      Independence and Capability                                                                                                          Assurance Conclusions
 The team of InFaith has performed this assurance work independently.                                                                  Report.
 sional training on the GRI Standards issued by the Global Reporting Initiative, AA1000AS v3, ISO 14001, ISO 26000, SA 8000,           conclusions are as follows
 EcoVadis global supply chain rating and other sustainability-related standards and have adequate understanding and practical
                                                                                                                                                                 Hapharm Group has announced major topics that will have substantial in?uence and impact on the evalua-
 experience in relevant international principles, evaluation systems and assurance standards.
                                                                                                                                        Inclusivity              tion, decision-making, actions and performance of the organization and its stakeholders, and judged and
                                                                                                                                                                 improved the management and performance of the issues.
      Assurance Statement
 ty of InFaith to conduct an assurance based on the scope as described herein, and to provide professional assurance opinions to        Materiality              organization and its stakeholders' assessments, decision-making, actions, and performance. The company
 the Report readers and stakeholders.                                                                                                                            has also conducted judgments and improvements on the management and performance of these topics.
                                                                                                                                                                 Hapharm Group has implemented relevant policies, and is able to respond to issues that concern the stake-
 and guarantee conclusion for the matters within the scope de?ned in the Report. In addition to providing independent assurance         Responsiveness
                                                                                                                                                                 holders in a timely manner.
 and making other statements of opinion on the facts of assurance under the conclusion, InFaith will not assume any legal or other
 liabilities for any inquiries for any other purposes, or for any other persons who read this Independent Assurance and Statement                                Hapharm Group has the adequate ability to identify substantive issues. It has implemented balanced and
 of Opinion.                                                                                                                                                     effective evaluation and disclosure methods, and has established a systematic process for monitoring,
 ance and Statement of Opinion, the Chinese version shall prevail.                                                                                               in an impartial and objective manner.
      Assurance Standard                                                                                                               3. Based on the procedures implemented and the evidence obtained by InFaith, we have found nothing that causes us to doubt
 InFaith adopts AA1000AS v3 type-1 Moderate assurance level, which includes Hapharm Group's evaluation of the compliance situation     the reliability and quality of the speci?c performance indicators selected in the Report.
 and degree of the four AA1000AS v3 assurance principles, including inclusiveness, substantiality, responsiveness and impact.
                                                                                                                                           Limitation
      Assurance Scope                                                                                                                  The assurance process was carried out at the location within the scope of the Report.
                                                                                                                                       Because there is no internationally recognized and commonly used standard for the evaluation and measurement of non-?nancial
                                                                                                                                       information, the application of different but acceptable information and measurement technologies may affect the comparability
 Report, excluding the data and information of Hapharm Group suppliers, contractors and other third parties.
                                                                                                                                       with other institutions.
 the four assurance principles in AA1000AS v3.
                                                                                                                                       If you have any advice for this Independent Assurance and Statement of Opinion, you
                                                                                                                                       may contact:
      Assurance Process and Work
                                                                                                                                       Tel: 021-20740303
 In order to gather evidence relevant to the formation of the conclusion, InFaith has done the following work:                         Email: esg@infaith.com.cn
 processes of the ful?llment of its environmental, social and governance responsibilities.                                             New District, Shanghai
 evidence for the claims made in the Report.                                                                                                                                                                                              For and on behalf of InFaith Consulting
 expectations and demands, the speci?c communication channels between both parties, and how Hapharm Group responds to
 their expectations and demands.
                                                                                                                                                                                                                                                            Shanghai, April 2026
HARBIN PHARMACEUTICAL GROUP CO., LTD.
Address: No.7 Qunli Avenue, Daoli District, Harbin City, Heilongjiang Province
Tel:0451-5187 0077
https://www.hayao.com/

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